Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2002 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/2669 |
Resumo: | P. 7-10,Jan-Fev. |
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D'Oliveira Junior, ArgemiroMachado, Paulo Roberto LimaBacellar, Maria Olívia Amado RamosCheng, Lay HarAlmeida, Roque Pacheco deCarvalho Filho, Edgar Marcelino deD'Oliveira Junior, ArgemiroMachado, Paulo Roberto LimaBacellar, Maria Olívia Amado RamosCheng, Lay HarAlmeida, Roque Pacheco deCarvalho Filho, Edgar Marcelino de2011-09-12T12:56:37Z2011-09-12T12:56:37Z20020037-8682http://www.repositorio.ufba.br/ri/handle/ri/2669v. 35, n. 1.P. 7-10,Jan-Fev.Para avaliar se os níveis séricos de IFN-g e TNF-a podem ser usados como marcadores da resposta terapêutica na leishmaniose cutânea, 54 pacientes com história de uma única lesão ulcerada com duração de até 30 dias foram arrolados para o estudo. IFN-g e TNF-a foram mensurados por ELISA no sobrenadante de cultura de linfócitos, antes e 60 dias após início da terapia. Cicatrização completa da lesão 60 dias após o tratamento foi considerada critério de cura. Os níveis de IFN-g e TNF-a foram similares em ambos os grupos antes da terapia. Houve tendência de aumento dos níveis de IFN-g nos pacientes curados aos 60 dias, os valores não alcançam significância estatística. Em ambos os grupos de pacientes, os níveis iniciais de TNF-a foram semelhantes antes da terapia e caíram significantemente após tratamento independente da cura ou manutenção da lesão ativa.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-09-12T12:56:37Z No. of bitstreams: 1 13164.pdf: 82743 bytes, checksum: e021d3f31a9761bc2665706a1081739e (MD5)Made available in DSpace on 2011-09-12T12:56:37Z (GMT). No. of bitstreams: 1 13164.pdf: 82743 bytes, checksum: e021d3f31a9761bc2665706a1081739e (MD5) Previous issue date: 2002UberabaIFN-g. TNF-aCitocinasResposta clínicaLeishmaniose cutâneaCytokineClinical outcomeCutaneous leishmaniasisEvaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasisRevista da Sociedade Brasileira de Medicina Tropicalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINAL13164.pdf13164.pdfapplication/pdf82743https://repositorio.ufba.br/bitstream/ri/2669/1/13164.pdfe021d3f31a9761bc2665706a1081739eMD51LICENSElicense.txtlicense.txttext/plain1906https://repositorio.ufba.br/bitstream/ri/2669/2/license.txt070c3cceda76977a018822f9b0cdf866MD52TEXT13164.pdf.txt13164.pdf.txtExtracted texttext/plain17442https://repositorio.ufba.br/bitstream/ri/2669/3/13164.pdf.txt3c52d035f8590882c7bcd095499e41ebMD53ri/26692022-07-05 14:03:09.582oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:09Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| dc.title.alternative.pt_BR.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical |
| title |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| spellingShingle |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis D'Oliveira Junior, Argemiro IFN-g. TNF-a Citocinas Resposta clínica Leishmaniose cutânea Cytokine Clinical outcome Cutaneous leishmaniasis |
| title_short |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| title_full |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| title_fullStr |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| title_full_unstemmed |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| title_sort |
Evaluation of IFN-g and TNF-a as immunological markers of clinical outcome in cutaneous leishmaniasis |
| author |
D'Oliveira Junior, Argemiro |
| author_facet |
D'Oliveira Junior, Argemiro Machado, Paulo Roberto Lima Bacellar, Maria Olívia Amado Ramos Cheng, Lay Har Almeida, Roque Pacheco de Carvalho Filho, Edgar Marcelino de |
| author_role |
author |
| author2 |
Machado, Paulo Roberto Lima Bacellar, Maria Olívia Amado Ramos Cheng, Lay Har Almeida, Roque Pacheco de Carvalho Filho, Edgar Marcelino de |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
D'Oliveira Junior, Argemiro Machado, Paulo Roberto Lima Bacellar, Maria Olívia Amado Ramos Cheng, Lay Har Almeida, Roque Pacheco de Carvalho Filho, Edgar Marcelino de D'Oliveira Junior, Argemiro Machado, Paulo Roberto Lima Bacellar, Maria Olívia Amado Ramos Cheng, Lay Har Almeida, Roque Pacheco de Carvalho Filho, Edgar Marcelino de |
| dc.subject.por.fl_str_mv |
IFN-g. TNF-a Citocinas Resposta clínica Leishmaniose cutânea Cytokine Clinical outcome Cutaneous leishmaniasis |
| topic |
IFN-g. TNF-a Citocinas Resposta clínica Leishmaniose cutânea Cytokine Clinical outcome Cutaneous leishmaniasis |
| description |
P. 7-10,Jan-Fev. |
| publishDate |
2002 |
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2002 |
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2011-09-12T12:56:37Z |
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2011-09-12T12:56:37Z |
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0037-8682 |
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v. 35, n. 1. |
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0037-8682 v. 35, n. 1. |
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