Regression splines in the time-dependent coefficient rates model for recurrent event data
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/13732 |
Resumo: | Texto completo: acesso restrito. p. 5890-5906 |
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Amorim, Leila Denise Alves FerreiraCai, JianwenZeng, DonglinBarreto, Mauricio LimaAmorim, Leila Denise Alves FerreiraCai, JianwenZeng, DonglinBarreto, Mauricio Lima2013-11-19T14:13:15Z20080277-6715http://repositorio.ufba.br/ri/handle/ri/13732v. 27, n. 28Texto completo: acesso restrito. p. 5890-5906Many epidemiologic studies involve the occurrence of recurrent events and much attention has been given for the development of modeling techniques that take into account the dependence structure of multiple event data. This paper presents a time-dependent coefficient rates model that incorporates regression splines in its estimation procedure. Such methods would be appropriate in situations where the effect of an exposure or covariates changes over time in recurrent event data settings. The finite sample properties of the estimators are studied via simulation. Using data from a randomized community trial that was designed to evaluate the effect of vitamin A supplementation on recurrent diarrheal episodes in small children, we model the functional form of the treatment effect on the time to the occurrence of diarrhea. The results describe how this effect varies over time. In summary, we observed a major impact of the vitamin A supplementation on diarrhea after 2 months of the dosage, with the effect diminishing after the third dosage. The proposed method can be viewed as a flexible alternative to the marginal rates model with constant effect in situations where the effect of interest may vary over time.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-11-19T14:13:15Z No. of bitstreams: 1 10.1002-sim.3400.pdf: 181138 bytes, checksum: 0e846ea7fb1f49fc09b2499df09fb226 (MD5)Made available in DSpace on 2013-11-19T14:13:15Z (GMT). No. of bitstreams: 1 10.1002-sim.3400.pdf: 181138 bytes, checksum: 0e846ea7fb1f49fc09b2499df09fb226 (MD5) Previous issue date: 2008http://dx.doi.org/10.1002/sim.3400reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBARegression splinesRecurrent time-to-event dataTime-dependent coefficientMarginal rates modelRegression splines in the time-dependent coefficient rates model for recurrent event dataStatistics in Medicineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL10.1002-sim.3400.pdf10.1002-sim.3400.pdfapplication/pdf181138https://repositorio.ufba.br/bitstream/ri/13732/1/10.1002-sim.3400.pdf0e846ea7fb1f49fc09b2499df09fb226MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/13732/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT10.1002-sim.3400.pdf.txt10.1002-sim.3400.pdf.txtExtracted texttext/plain51942https://repositorio.ufba.br/bitstream/ri/13732/3/10.1002-sim.3400.pdf.txt57918d0861c53bb49a03b1c623833bc2MD53ri/137322022-08-08 13:17:27.832oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:27Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
dc.title.alternative.pt_BR.fl_str_mv |
Statistics in Medicine |
title |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
spellingShingle |
Regression splines in the time-dependent coefficient rates model for recurrent event data Amorim, Leila Denise Alves Ferreira Regression splines Recurrent time-to-event data Time-dependent coefficient Marginal rates model |
title_short |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
title_full |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
title_fullStr |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
title_full_unstemmed |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
title_sort |
Regression splines in the time-dependent coefficient rates model for recurrent event data |
author |
Amorim, Leila Denise Alves Ferreira |
author_facet |
Amorim, Leila Denise Alves Ferreira Cai, Jianwen Zeng, Donglin Barreto, Mauricio Lima |
author_role |
author |
author2 |
Cai, Jianwen Zeng, Donglin Barreto, Mauricio Lima |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Amorim, Leila Denise Alves Ferreira Cai, Jianwen Zeng, Donglin Barreto, Mauricio Lima Amorim, Leila Denise Alves Ferreira Cai, Jianwen Zeng, Donglin Barreto, Mauricio Lima |
dc.subject.por.fl_str_mv |
Regression splines Recurrent time-to-event data Time-dependent coefficient Marginal rates model |
topic |
Regression splines Recurrent time-to-event data Time-dependent coefficient Marginal rates model |
description |
Texto completo: acesso restrito. p. 5890-5906 |
publishDate |
2008 |
dc.date.issued.fl_str_mv |
2008 |
dc.date.accessioned.fl_str_mv |
2013-11-19T14:13:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/13732 |
dc.identifier.issn.none.fl_str_mv |
0277-6715 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 27, n. 28 |
identifier_str_mv |
0277-6715 v. 27, n. 28 |
url |
http://repositorio.ufba.br/ri/handle/ri/13732 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1002/sim.3400 |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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