Influência do consumo das linhaças marrom e dourada sobre a composição corporal, o perfil lipídico e o estresse oxidativo em mulheres com excesso de peso em perimenopausa

• Autor(a) principal: Gava, Ana Paula
• Data de Publicação: 2015
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da Universidade Federal do Espírito Santo (riUfes)
• Texto Completo: http://repositorio.ufes.br/handle/10/4925
• topic: Flaxseed; Perimenopause; Antioxidant; Oxidative stress; Lipid profile; Anthropometry; Perfil lipídico; Perimenopausa; Antioxidante; Ciência e Tecnologia de Alimentos; Linhaça; Menopausa; Antioxidantes; Stress oxidativo; Antropometria; 664

Perimenopause is characterized by reduced estrogen production, which leads to increased oxidative stress body and consequently to vascular endothelial dysfunction and inflammation, leading to increased risk of cardiovascular disease. Flaxseed has considerable amounts of dietary fiber, lignans antioxidants, a-linolenic acid (ALA) and phenolic compounds, which can mitigate the adverse effects of perimenopause. This study aimed to determine the influence of consumption of brown and golden linseeds on anthropometric and lipid profiles and oxidative stress markers in overweight women in perimenopause. The brown and golden flaxseed were evaluated in terms of chemical composition and concentration of phenolic compounds and antioxidant activity. The study was applied on 30 volunteers, divided into three groups, the control group (which received no linseed), brown flaxseed group and golden flaxseed group. All groups received a food planning with a reduction of 250 kcal / day and nutritional guidelines. Women of LM and LD groups were supplemented by 12 weeks with 40 g of flaxseed flour per day. After the trial period parameters evaluated were anthropometric profile and body composition, blood pressure, lipid profile, serum antioxidant capacity and lipid peroxidation, for dosage of malondialdehyde and oxidized low-density lipoprotein. To do this, venous blood samples were collected at the beginning and in the end of the intervention period. It was held t test (a = 5%) compared to the averages of final and initial time of each group and ANOVA followed by Tukey (a = 5%), for comparison between groups. The brown flaxseed showed the highest antioxidant activity and no difference between the linseeds on the concentration of phenolic compounds. The golden flaxseed was the most effective in reducing weight, BMI, waist circumference and fat mass. And it was the only group different to the control group for LDL-c fraction. However, it was not verified an increase in blood antioxidant activity nor a reduction in serum lipid peroxidation after supplementation with flaxseed in the experimental groups. It can be concluded that the golden flaxseed was the most effective for the decrease of anthropometric parameters and LDL-c.