Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | http://repositorio.ufla.br/jspui/handle/1/13375 |
Resumo: | The objective of this study was to evaluate antioxidant substances, dietary fiber and antioxidant activity of guava leaves, and evaluate their amelioration hypercholesterolemia in rats. The leaves were dried and crushed into granulated powder. The active ingredient of the leaf powder was extracted by an ethanol/acetone mixture and called ethanol/acetone extract flour. Dietary fiber, vitamin C, beta-carotene, phenolic compounds and antioxidant activity were determined in the flours. Thirty (30) rats were used in the present study and categorized into: hypercholesterolemic control, non-hypercholesterolemic rats treated with ethanol/acetone extract flour, hypercholesterolemic rats treated with ethanol/acetone extract flour, non-hypercholesterolemic rats treated with leaf flours, and hypercholesterolemic rats treated with leaf flours. The animals were subjected to experimental hypercholesterolemia and treatment with flours for 42 days. At the end of the treatment, liver weight index versus body weight index, total hepatic lipids, C reactive protein, total cholesterol and fractions were evaluated. The treated hypercholeterolemic animals showed a reduction in total and fractionated cholesterol levels, but no difference was observed in the ratio liver weight index versus body weight index, total hepatic lipids and C reactive protein. It is concluded that guava leaves are a significant source of dietary fiber, phenolic compounds, vitamin C, beta-carotene, besides presenting antioxidant activity and hypocholesterolemic potential. |
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Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic ratsGuava leaves - Nutritional characteristicsGuava leaves - Antioxidant activityHypercholesterolemia - TreatmentGuava leaves - Hypocholesterolemic potentialFolhas de goiaba - Características nutricionaisFolhas de goiaba - Atividade antioxidanteHipercolesterolemia - TratamentoFolhas de goiaba - Potencial hipocolesterolémicoThe objective of this study was to evaluate antioxidant substances, dietary fiber and antioxidant activity of guava leaves, and evaluate their amelioration hypercholesterolemia in rats. The leaves were dried and crushed into granulated powder. The active ingredient of the leaf powder was extracted by an ethanol/acetone mixture and called ethanol/acetone extract flour. Dietary fiber, vitamin C, beta-carotene, phenolic compounds and antioxidant activity were determined in the flours. Thirty (30) rats were used in the present study and categorized into: hypercholesterolemic control, non-hypercholesterolemic rats treated with ethanol/acetone extract flour, hypercholesterolemic rats treated with ethanol/acetone extract flour, non-hypercholesterolemic rats treated with leaf flours, and hypercholesterolemic rats treated with leaf flours. The animals were subjected to experimental hypercholesterolemia and treatment with flours for 42 days. At the end of the treatment, liver weight index versus body weight index, total hepatic lipids, C reactive protein, total cholesterol and fractions were evaluated. The treated hypercholeterolemic animals showed a reduction in total and fractionated cholesterol levels, but no difference was observed in the ratio liver weight index versus body weight index, total hepatic lipids and C reactive protein. It is concluded that guava leaves are a significant source of dietary fiber, phenolic compounds, vitamin C, beta-carotene, besides presenting antioxidant activity and hypocholesterolemic potential.Academic Journals2017-07-17T11:49:31Z2017-07-17T11:49:31Z2014-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfFREIRE, J. M. et al. Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats. African Journal of Biotechnology, [S. l.], v. 13, n. 46, p. 4289-4293, Nov. 2014.http://repositorio.ufla.br/jspui/handle/1/13375African Journal of Biotechnologyreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAFreire, Juliana MesquitaAbreu, Celeste Maria Patto deDuarte, Stella Maris da SilveiraPaula, Fernanda Borges Araujo deLima, Adriene RibeiroLima, Rafaella Araujo ZambaldiRocha, Denise AlvarengaSimão, Anderson Assaidinfo:eu-repo/semantics/openAccesseng2017-07-17T11:49:31Zoai:localhost:1/13375Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2017-07-17T11:49:31Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
title |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
spellingShingle |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats Freire, Juliana Mesquita Guava leaves - Nutritional characteristics Guava leaves - Antioxidant activity Hypercholesterolemia - Treatment Guava leaves - Hypocholesterolemic potential Folhas de goiaba - Características nutricionais Folhas de goiaba - Atividade antioxidante Hipercolesterolemia - Tratamento Folhas de goiaba - Potencial hipocolesterolémico |
title_short |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
title_full |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
title_fullStr |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
title_full_unstemmed |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
title_sort |
Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats |
author |
Freire, Juliana Mesquita |
author_facet |
Freire, Juliana Mesquita Abreu, Celeste Maria Patto de Duarte, Stella Maris da Silveira Paula, Fernanda Borges Araujo de Lima, Adriene Ribeiro Lima, Rafaella Araujo Zambaldi Rocha, Denise Alvarenga Simão, Anderson Assaid |
author_role |
author |
author2 |
Abreu, Celeste Maria Patto de Duarte, Stella Maris da Silveira Paula, Fernanda Borges Araujo de Lima, Adriene Ribeiro Lima, Rafaella Araujo Zambaldi Rocha, Denise Alvarenga Simão, Anderson Assaid |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Freire, Juliana Mesquita Abreu, Celeste Maria Patto de Duarte, Stella Maris da Silveira Paula, Fernanda Borges Araujo de Lima, Adriene Ribeiro Lima, Rafaella Araujo Zambaldi Rocha, Denise Alvarenga Simão, Anderson Assaid |
dc.subject.por.fl_str_mv |
Guava leaves - Nutritional characteristics Guava leaves - Antioxidant activity Hypercholesterolemia - Treatment Guava leaves - Hypocholesterolemic potential Folhas de goiaba - Características nutricionais Folhas de goiaba - Atividade antioxidante Hipercolesterolemia - Tratamento Folhas de goiaba - Potencial hipocolesterolémico |
topic |
Guava leaves - Nutritional characteristics Guava leaves - Antioxidant activity Hypercholesterolemia - Treatment Guava leaves - Hypocholesterolemic potential Folhas de goiaba - Características nutricionais Folhas de goiaba - Atividade antioxidante Hipercolesterolemia - Tratamento Folhas de goiaba - Potencial hipocolesterolémico |
description |
The objective of this study was to evaluate antioxidant substances, dietary fiber and antioxidant activity of guava leaves, and evaluate their amelioration hypercholesterolemia in rats. The leaves were dried and crushed into granulated powder. The active ingredient of the leaf powder was extracted by an ethanol/acetone mixture and called ethanol/acetone extract flour. Dietary fiber, vitamin C, beta-carotene, phenolic compounds and antioxidant activity were determined in the flours. Thirty (30) rats were used in the present study and categorized into: hypercholesterolemic control, non-hypercholesterolemic rats treated with ethanol/acetone extract flour, hypercholesterolemic rats treated with ethanol/acetone extract flour, non-hypercholesterolemic rats treated with leaf flours, and hypercholesterolemic rats treated with leaf flours. The animals were subjected to experimental hypercholesterolemia and treatment with flours for 42 days. At the end of the treatment, liver weight index versus body weight index, total hepatic lipids, C reactive protein, total cholesterol and fractions were evaluated. The treated hypercholeterolemic animals showed a reduction in total and fractionated cholesterol levels, but no difference was observed in the ratio liver weight index versus body weight index, total hepatic lipids and C reactive protein. It is concluded that guava leaves are a significant source of dietary fiber, phenolic compounds, vitamin C, beta-carotene, besides presenting antioxidant activity and hypocholesterolemic potential. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-11 2017-07-17T11:49:31Z 2017-07-17T11:49:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
FREIRE, J. M. et al. Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats. African Journal of Biotechnology, [S. l.], v. 13, n. 46, p. 4289-4293, Nov. 2014. http://repositorio.ufla.br/jspui/handle/1/13375 |
identifier_str_mv |
FREIRE, J. M. et al. Nutritional characteristics of guava leaves and its effects on lipid metabolism in hypercholesterolemic rats. African Journal of Biotechnology, [S. l.], v. 13, n. 46, p. 4289-4293, Nov. 2014. |
url |
http://repositorio.ufla.br/jspui/handle/1/13375 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Academic Journals |
publisher.none.fl_str_mv |
Academic Journals |
dc.source.none.fl_str_mv |
African Journal of Biotechnology reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
instname_str |
Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
collection |
Repositório Institucional da UFLA |
repository.name.fl_str_mv |
Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
_version_ |
1784550177785249792 |