Relationship between Helicobacter pylori infection and metabolic diseases: an integrative review: Relationship between Helicobacter pylori infection and metabolic diseases

• Autor(a) principal: de Sousa Moraes , Felipe Augusto
• Data de Publicação: 2023
• Outros Autores: Ribeiro Maximo, Gabriel, Sampaio Soares, Giovana Alice, Barbosa, Mônica Santiago
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125129
• topic: Helicobacter pylori; Infecção; Doenças metabólicas; Diabetes; Síndrome metabólica.; Helicobacter pylori; Extragastric diseases; Metabolic diseases; Diabetes; Metabolic syndrome.

Helicobacter pylori is a Gram-negative bacterium that affects about 50% of the world population. The H. pylori infection is associated with some gastric diseases. However, more recent studies have demonstrated the etiology of the microorganism in extra gastric diseases, such as metabolic diseases. The objective of this work was to conduct a search in the literature of articles that evaluated the association of H. pylori infection with metabolic diseases, with a focus on diabetes and metabolic syndrome (MS). The following databases were used, PubMed, Medline, LILACS and SciElo. Combined terms were used together with the Boolean operator “AND” in Portuguese and English. The result of the bibliographic survey totaled 31 articles. H. pylori infection is possibly related to diabetes and MS. The relationship may be due to chronic inflammation, reduced gastrointestinal movements, lack of secretion of gastric acid and interference in the production or secretion of some hormones. Although studies show that the eradication of the microorganism favors the improvement of glycemic indexes and that infected individuals had a higher prevalence of MS, more research is required. The understanding of the etiology of H. pylori infection in metabolic diseases, can assist in public policies for the eradication of the bacterium.