Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)

Detalhes bibliográficos
Autor(a) principal: Parodi, Thaylise Vey
Data de Publicação: 2010
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações do UFSM
Texto Completo: http://repositorio.ufsm.br/handle/1/27321
Resumo: The use of natural products is ancient and the importance of these natural resources is being investigated in recent years. Brazil is rich in plant diversity is a rich source of natural products. Fish farming has intensified its production and this contributes to the emergence of diseases. Aeromonas are represented in fish losses due to the pathology they cause and the resistance to antibiotics. Aloysia triphylla is a shrub grown in our region and is used in folk medicine due to different properties, including antimicrobial activity. For methods of extraction using supercritical carbon dioxide is possible to obtain high-purity product, free of solvents and of excellent quality. This study is to evaluate the activity of Aloysia triphylla against Aeromonas sp. based on extracts obtained with supercritical carbon dioxide under different conditions of temperature and pressure, and check the chemical composition of plant material. The results obtained for extracts in the conditions of 30 °C and 100 bar, 70 °C and 200 bar and 50 °C and 150 bar consisted mainly of monoterpenes present as major component E-citral, while for 30 °C and 200 bar predominated limonene. The extract obtained at 70 °C and 100 bar was predominant sesquiterpene caryophyllene oxide and only at 50 °C and 150 bar was detected squalene. The condition of 30 °C and 100 bar showed better activity against Aeromonas sp.. Aloysia triphylla showed bactericidal activity against the genus Aeromonas, but its activity differs from the extraction of condition as a result of the components present.
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spelling 2022-12-13T14:11:20Z2022-12-13T14:11:20Z2010-01-28http://repositorio.ufsm.br/handle/1/27321The use of natural products is ancient and the importance of these natural resources is being investigated in recent years. Brazil is rich in plant diversity is a rich source of natural products. Fish farming has intensified its production and this contributes to the emergence of diseases. Aeromonas are represented in fish losses due to the pathology they cause and the resistance to antibiotics. Aloysia triphylla is a shrub grown in our region and is used in folk medicine due to different properties, including antimicrobial activity. For methods of extraction using supercritical carbon dioxide is possible to obtain high-purity product, free of solvents and of excellent quality. This study is to evaluate the activity of Aloysia triphylla against Aeromonas sp. based on extracts obtained with supercritical carbon dioxide under different conditions of temperature and pressure, and check the chemical composition of plant material. The results obtained for extracts in the conditions of 30 °C and 100 bar, 70 °C and 200 bar and 50 °C and 150 bar consisted mainly of monoterpenes present as major component E-citral, while for 30 °C and 200 bar predominated limonene. The extract obtained at 70 °C and 100 bar was predominant sesquiterpene caryophyllene oxide and only at 50 °C and 150 bar was detected squalene. The condition of 30 °C and 100 bar showed better activity against Aeromonas sp.. Aloysia triphylla showed bactericidal activity against the genus Aeromonas, but its activity differs from the extraction of condition as a result of the components present.A utilização de produtos naturais é milenar e a importância destes recursos naturais está sendo investigada nos últimos anos. O Brasil é rico em diversidade vegetal sendo uma fonte rica de produtos naturais. A piscicultura vem aumentando sua produção e isto contribui para o surgimento de doenças. Bactérias do gênero Aeromonas têm representado perdas na piscicultura em decorrência da patologia que ocasionam e da resistência a antimicrobianos. Aloysia triphylla é um arbusto cultivado em nossa região sendo utilizado na medicina popular devido a diferentes propriedades, entre elas a atividade antimicrobiana. Por métodos de extração utilizando dióxido de carbono supercrítico é possível obter produto de alta pureza, livres de solventes e de excelente qualidade. O objetivo do trabalho é avaliar a atividade de Aloysia triphylla contra Aeromonas sp. baseado em extratos obtidos com dióxido de carbono supercrítico em diferentes condições de temperatura e pressão, bem como verificar a composição química do material vegetal. Os resultados obtidos para extratos nas condições de 30 °C e 100 bar, 70 °C e 200 bar, e 50 °C e 150 bar consistiram principalmente de monoterpenóides apresentando como maior componente E-citral, enquanto que para 30oC and 200 bar predominou o limoneno. O extrato obtido a 70 °C e 100 bar predominou o sesquiterpenóide óxido de cariofileno e somente em 50 °C e 150 bar foi detectado esqualeno. A condição a 30 oC and 100 bar apresentou melhor atividade contra Aeromonas sp.. Aloysia triphylla apresentou atividade bactericida contra o gênero Aeromonas, porém sua atividade difere da condição de extração em conseqüência dos componentes presentes.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESporUniversidade Federal de Santa MariaCentro de Ciências da SaúdePrograma de Pós-Graduação em FarmacologiaUFSMBrasilFarmacologiaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAloysia triphyllaAeromonas sp.Dióxido de carbono supercríticoSupercritical carbon dioxideCNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIAAtividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)Antibacterial activity and chemical composition of Aloysia triphylla (L’Hérit) Britton extracts obtained by supercritical fluid (CO2)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisBaldisserotto, Bernardohttp://lattes.cnpq.br/1036046601275319Rates, Stela Maris KuzeAlves, Sydney Hartzhttp://lattes.cnpq.br/4183167775476307Parodi, Thaylise Vey2010000000006006006006006004948adb8-9408-43d6-82b1-b9df8481e3da20d980d4-a735-48d0-b31a-831cbda1ee921a936436-2c3e-4a3c-8dba-ff3790b3ab09d222d3db-5dc1-4604-ac47-2d6968c2c477reponame:Biblioteca Digital de Teses e Dissertações do UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.ufsm.br/bitstream/1/27321/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81956http://repositorio.ufsm.br/bitstream/1/27321/3/license.txt2f0571ecee68693bd5cd3f17c1e075dfMD53ORIGINALDIS_PPGFARMACOLOGIA_2010_PARODI_THAYLISE.pdfDIS_PPGFARMACOLOGIA_2010_PARODI_THAYLISE.pdfDissertação de Mestradoapplication/pdf452405http://repositorio.ufsm.br/bitstream/1/27321/1/DIS_PPGFARMACOLOGIA_2010_PARODI_THAYLISE.pdf9f9a977030adb9fba0d1f989616c23caMD511/273212022-12-13 11:11:20.721oai:repositorio.ufsm.br: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 Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2022-12-13T14:11:20Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.por.fl_str_mv Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
dc.title.alternative.eng.fl_str_mv Antibacterial activity and chemical composition of Aloysia triphylla (L’Hérit) Britton extracts obtained by supercritical fluid (CO2)
title Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
spellingShingle Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
Parodi, Thaylise Vey
Aloysia triphylla
Aeromonas sp.
Dióxido de carbono supercrítico
Supercritical carbon dioxide
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
title_short Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
title_full Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
title_fullStr Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
title_full_unstemmed Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
title_sort Atividade antibacteriana e composição química dos extratos de Aloysia triphylla (L’Hérit) Britton obtidos por fluído supercrítico (CO2)
author Parodi, Thaylise Vey
author_facet Parodi, Thaylise Vey
author_role author
dc.contributor.advisor1.fl_str_mv Baldisserotto, Bernardo
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/1036046601275319
dc.contributor.referee1.fl_str_mv Rates, Stela Maris Kuze
dc.contributor.referee2.fl_str_mv Alves, Sydney Hartz
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/4183167775476307
dc.contributor.author.fl_str_mv Parodi, Thaylise Vey
contributor_str_mv Baldisserotto, Bernardo
Rates, Stela Maris Kuze
Alves, Sydney Hartz
dc.subject.por.fl_str_mv Aloysia triphylla
Aeromonas sp.
Dióxido de carbono supercrítico
topic Aloysia triphylla
Aeromonas sp.
Dióxido de carbono supercrítico
Supercritical carbon dioxide
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
dc.subject.eng.fl_str_mv Supercritical carbon dioxide
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
description The use of natural products is ancient and the importance of these natural resources is being investigated in recent years. Brazil is rich in plant diversity is a rich source of natural products. Fish farming has intensified its production and this contributes to the emergence of diseases. Aeromonas are represented in fish losses due to the pathology they cause and the resistance to antibiotics. Aloysia triphylla is a shrub grown in our region and is used in folk medicine due to different properties, including antimicrobial activity. For methods of extraction using supercritical carbon dioxide is possible to obtain high-purity product, free of solvents and of excellent quality. This study is to evaluate the activity of Aloysia triphylla against Aeromonas sp. based on extracts obtained with supercritical carbon dioxide under different conditions of temperature and pressure, and check the chemical composition of plant material. The results obtained for extracts in the conditions of 30 °C and 100 bar, 70 °C and 200 bar and 50 °C and 150 bar consisted mainly of monoterpenes present as major component E-citral, while for 30 °C and 200 bar predominated limonene. The extract obtained at 70 °C and 100 bar was predominant sesquiterpene caryophyllene oxide and only at 50 °C and 150 bar was detected squalene. The condition of 30 °C and 100 bar showed better activity against Aeromonas sp.. Aloysia triphylla showed bactericidal activity against the genus Aeromonas, but its activity differs from the extraction of condition as a result of the components present.
publishDate 2010
dc.date.issued.fl_str_mv 2010-01-28
dc.date.accessioned.fl_str_mv 2022-12-13T14:11:20Z
dc.date.available.fl_str_mv 2022-12-13T14:11:20Z
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rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Farmacologia
dc.publisher.initials.fl_str_mv UFSM
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Farmacologia
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
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