Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning

Detalhes bibliográficos
Autor(a) principal: Lorenzoni, Diego Coelho
Data de Publicação: 2012
Outros Autores: Fracalossi, Ana Carolina Cuzzuol [UNIFESP], Carlin, Viviane [UNIFESP], Ribeiro, Daniel Araki [UNIFESP], Sant' Anna, Eduardo Franzotti
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.2319/072311-468.1
http://repositorio.unifesp.br/handle/11600/35033
Resumo: Objectives: To evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated buccal mucosa cells from children undergoing orthodontic radiographs.Materials and Methods: A total of 25 healthy children undergoing orthodontic therapy partook in a complete set of orthodontic radiographs (lateral cephalographic, posteroanterior cephalographic, panoramic, full periapical exam, and bitewing). the micronucleus test in the buccal exfoliated cells was applied. the paired-samples t-test and the Wilcoxon test were used to compare the frequencies of alterations before and after X-ray exposure.Results: We found no statistically significant differences (P > .05) between micronucleated buccal mucosa cells before and after exposure to radiation. However, radiation did cause other nuclear alterations closely related to cytotoxicity (P = .007).Conclusion: According to the micronucleus test, the complete set of radiographs requested in the orthodontic planning may not be a factor that induces chromosomal damage, but it is able to promote cytotoxicity. (Angle Orthod. 2012;82:585-590.)
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spelling Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planningMicronucleus testBuccal mucosa cellsDental radiographyObjectives: To evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated buccal mucosa cells from children undergoing orthodontic radiographs.Materials and Methods: A total of 25 healthy children undergoing orthodontic therapy partook in a complete set of orthodontic radiographs (lateral cephalographic, posteroanterior cephalographic, panoramic, full periapical exam, and bitewing). the micronucleus test in the buccal exfoliated cells was applied. the paired-samples t-test and the Wilcoxon test were used to compare the frequencies of alterations before and after X-ray exposure.Results: We found no statistically significant differences (P > .05) between micronucleated buccal mucosa cells before and after exposure to radiation. However, radiation did cause other nuclear alterations closely related to cytotoxicity (P = .007).Conclusion: According to the micronucleus test, the complete set of radiographs requested in the orthodontic planning may not be a factor that induces chromosomal damage, but it is able to promote cytotoxicity. (Angle Orthod. 2012;82:585-590.)Univ Fed Rio de Janeiro, Dept Orthodont, Ilha Fundao Rio de Janeiro RJ, BR-21941617 Rio de Janeiro, BrazilUniversidade Federal de São Paulo, Dept Pathol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Hlth Sci, Santos, BrazilUniversidade Federal de São Paulo, Dept Pathol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Hlth Sci, Santos, BrazilWeb of ScienceE H Angle Education Research Foundation, IncUniversidade Federal do Rio de Janeiro (UFRJ)Universidade Federal de São Paulo (UNIFESP)Lorenzoni, Diego CoelhoFracalossi, Ana Carolina Cuzzuol [UNIFESP]Carlin, Viviane [UNIFESP]Ribeiro, Daniel Araki [UNIFESP]Sant' Anna, Eduardo Franzotti2016-01-24T14:27:24Z2016-01-24T14:27:24Z2012-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion585-590application/pdfhttp://dx.doi.org/10.2319/072311-468.1Angle Orthodontist. Newton N: E H Angle Education Research Foundation, Inc, v. 82, n. 4, p. 585-590, 2012.10.2319/072311-468.1WOS000306380300002.pdf0003-3219http://repositorio.unifesp.br/handle/11600/35033WOS:000306380300002engAngle Orthodontistinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-08T13:50:28Zoai:repositorio.unifesp.br/:11600/35033Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-08T13:50:28Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
title Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
spellingShingle Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
Lorenzoni, Diego Coelho
Micronucleus test
Buccal mucosa cells
Dental radiography
title_short Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
title_full Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
title_fullStr Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
title_full_unstemmed Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
title_sort Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
author Lorenzoni, Diego Coelho
author_facet Lorenzoni, Diego Coelho
Fracalossi, Ana Carolina Cuzzuol [UNIFESP]
Carlin, Viviane [UNIFESP]
Ribeiro, Daniel Araki [UNIFESP]
Sant' Anna, Eduardo Franzotti
author_role author
author2 Fracalossi, Ana Carolina Cuzzuol [UNIFESP]
Carlin, Viviane [UNIFESP]
Ribeiro, Daniel Araki [UNIFESP]
Sant' Anna, Eduardo Franzotti
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Lorenzoni, Diego Coelho
Fracalossi, Ana Carolina Cuzzuol [UNIFESP]
Carlin, Viviane [UNIFESP]
Ribeiro, Daniel Araki [UNIFESP]
Sant' Anna, Eduardo Franzotti
dc.subject.por.fl_str_mv Micronucleus test
Buccal mucosa cells
Dental radiography
topic Micronucleus test
Buccal mucosa cells
Dental radiography
description Objectives: To evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated buccal mucosa cells from children undergoing orthodontic radiographs.Materials and Methods: A total of 25 healthy children undergoing orthodontic therapy partook in a complete set of orthodontic radiographs (lateral cephalographic, posteroanterior cephalographic, panoramic, full periapical exam, and bitewing). the micronucleus test in the buccal exfoliated cells was applied. the paired-samples t-test and the Wilcoxon test were used to compare the frequencies of alterations before and after X-ray exposure.Results: We found no statistically significant differences (P > .05) between micronucleated buccal mucosa cells before and after exposure to radiation. However, radiation did cause other nuclear alterations closely related to cytotoxicity (P = .007).Conclusion: According to the micronucleus test, the complete set of radiographs requested in the orthodontic planning may not be a factor that induces chromosomal damage, but it is able to promote cytotoxicity. (Angle Orthod. 2012;82:585-590.)
publishDate 2012
dc.date.none.fl_str_mv 2012-07-01
2016-01-24T14:27:24Z
2016-01-24T14:27:24Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.2319/072311-468.1
Angle Orthodontist. Newton N: E H Angle Education Research Foundation, Inc, v. 82, n. 4, p. 585-590, 2012.
10.2319/072311-468.1
WOS000306380300002.pdf
0003-3219
http://repositorio.unifesp.br/handle/11600/35033
WOS:000306380300002
url http://dx.doi.org/10.2319/072311-468.1
http://repositorio.unifesp.br/handle/11600/35033
identifier_str_mv Angle Orthodontist. Newton N: E H Angle Education Research Foundation, Inc, v. 82, n. 4, p. 585-590, 2012.
10.2319/072311-468.1
WOS000306380300002.pdf
0003-3219
WOS:000306380300002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Angle Orthodontist
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 585-590
application/pdf
dc.publisher.none.fl_str_mv E H Angle Education Research Foundation, Inc
publisher.none.fl_str_mv E H Angle Education Research Foundation, Inc
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268385681211392

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