Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative

Detalhes bibliográficos
Autor(a) principal: Diaz, Gaspar
Data de Publicação: 2014
Outros Autores: Freitas, Michelle A. A. de, Ricci-Silva, Maria E., Diaz, Marisa A. N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: LOCUS Repositório Institucional da UFV
Texto Completo: http://dx.doi.org/10.3390/molecules19067429
http://www.locus.ufv.br/handle/123456789/12568
Resumo: An interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excellent yields. In turn, another new stereoselective and efficient strategy has also allowed for the preparation of a 2-oxazolidinone derivative in 34% overall yield from the Morita-Baylis-Hillman adduct. The antibacterial activity of this oxazolidinone was tested against Staphylococcus aureus strains isolated from animals with mastitis infections.
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spelling Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivativeEvans’ oxazolidinonesStereoselective synthesisMorita-baylis-hillman adductStaphylococcus aureusMastitis bovinaAn interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excellent yields. In turn, another new stereoselective and efficient strategy has also allowed for the preparation of a 2-oxazolidinone derivative in 34% overall yield from the Morita-Baylis-Hillman adduct. The antibacterial activity of this oxazolidinone was tested against Staphylococcus aureus strains isolated from animals with mastitis infections.Molecules2017-10-31T09:49:09Z2017-10-31T09:49:09Z2014-06-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlepdfapplication/pdf1420-3049http://dx.doi.org/10.3390/molecules19067429http://www.locus.ufv.br/handle/123456789/12568eng19(6), p.7429-7439, June 2014Diaz, GasparFreitas, Michelle A. A. deRicci-Silva, Maria E.Diaz, Marisa A. N.info:eu-repo/semantics/openAccessreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFV2024-07-12T06:53:10Zoai:locus.ufv.br:123456789/12568Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452024-07-12T06:53:10LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false
dc.title.none.fl_str_mv Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
title Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
spellingShingle Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
Diaz, Gaspar
Evans’ oxazolidinones
Stereoselective synthesis
Morita-baylis-hillman adduct
Staphylococcus aureus
Mastitis bovina
title_short Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
title_full Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
title_fullStr Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
title_full_unstemmed Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
title_sort Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
author Diaz, Gaspar
author_facet Diaz, Gaspar
Freitas, Michelle A. A. de
Ricci-Silva, Maria E.
Diaz, Marisa A. N.
author_role author
author2 Freitas, Michelle A. A. de
Ricci-Silva, Maria E.
Diaz, Marisa A. N.
author2_role author
author
author
dc.contributor.author.fl_str_mv Diaz, Gaspar
Freitas, Michelle A. A. de
Ricci-Silva, Maria E.
Diaz, Marisa A. N.
dc.subject.por.fl_str_mv Evans’ oxazolidinones
Stereoselective synthesis
Morita-baylis-hillman adduct
Staphylococcus aureus
Mastitis bovina
topic Evans’ oxazolidinones
Stereoselective synthesis
Morita-baylis-hillman adduct
Staphylococcus aureus
Mastitis bovina
description An interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excellent yields. In turn, another new stereoselective and efficient strategy has also allowed for the preparation of a 2-oxazolidinone derivative in 34% overall yield from the Morita-Baylis-Hillman adduct. The antibacterial activity of this oxazolidinone was tested against Staphylococcus aureus strains isolated from animals with mastitis infections.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-06
2017-10-31T09:49:09Z
2017-10-31T09:49:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv 1420-3049
http://dx.doi.org/10.3390/molecules19067429
http://www.locus.ufv.br/handle/123456789/12568
identifier_str_mv 1420-3049
url http://dx.doi.org/10.3390/molecules19067429
http://www.locus.ufv.br/handle/123456789/12568
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 19(6), p.7429-7439, June 2014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv pdf
application/pdf
dc.publisher.none.fl_str_mv Molecules
publisher.none.fl_str_mv Molecules
dc.source.none.fl_str_mv reponame:LOCUS Repositório Institucional da UFV
instname:Universidade Federal de Viçosa (UFV)
instacron:UFV
instname_str Universidade Federal de Viçosa (UFV)
instacron_str UFV
institution UFV
reponame_str LOCUS Repositório Institucional da UFV
collection LOCUS Repositório Institucional da UFV
repository.name.fl_str_mv LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)
repository.mail.fl_str_mv fabiojreis@ufv.br
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