Spot-test identification and rapid quantitative sequential analysis of dipyrone

Detalhes bibliográficos
Autor(a) principal: Tubino,M.
Data de Publicação: 2010
Outros Autores: Biondo,A. C., Vila,M. M. D. C., Pezza,L., Pezza,H. R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Eclética Química
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005
Resumo: A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1.
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spelling Spot-test identification and rapid quantitative sequential analysis of dipyronedipyronespot-testanalysisqualitativequantitativeA qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1.Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005Eclética Química v.35 n.1 2010reponame:Eclética Químicainstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESP10.1590/S0100-46702010000100005info:eu-repo/semantics/openAccessTubino,M.Biondo,A. C.Vila,M. M. D. C.Pezza,L.Pezza,H. R.eng2010-06-09T00:00:00Zoai:scielo:S0100-46702010000100005Revistahttp://revista.iq.unesp.br/ojs/index.php/ecletica/PUBhttps://revista.iq.unesp.br/ojs/index.php/ecletica/oaiecletica@ctrlk.com.br||ecletica@iq.unesp.br1678-46181678-4618opendoar:2010-06-09T00:00Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)false
dc.title.none.fl_str_mv Spot-test identification and rapid quantitative sequential analysis of dipyrone
title Spot-test identification and rapid quantitative sequential analysis of dipyrone
spellingShingle Spot-test identification and rapid quantitative sequential analysis of dipyrone
Tubino,M.
dipyrone
spot-test
analysis
qualitative
quantitative
title_short Spot-test identification and rapid quantitative sequential analysis of dipyrone
title_full Spot-test identification and rapid quantitative sequential analysis of dipyrone
title_fullStr Spot-test identification and rapid quantitative sequential analysis of dipyrone
title_full_unstemmed Spot-test identification and rapid quantitative sequential analysis of dipyrone
title_sort Spot-test identification and rapid quantitative sequential analysis of dipyrone
author Tubino,M.
author_facet Tubino,M.
Biondo,A. C.
Vila,M. M. D. C.
Pezza,L.
Pezza,H. R.
author_role author
author2 Biondo,A. C.
Vila,M. M. D. C.
Pezza,L.
Pezza,H. R.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Tubino,M.
Biondo,A. C.
Vila,M. M. D. C.
Pezza,L.
Pezza,H. R.
dc.subject.por.fl_str_mv dipyrone
spot-test
analysis
qualitative
quantitative
topic dipyrone
spot-test
analysis
qualitative
quantitative
description A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1.
publishDate 2010
dc.date.none.fl_str_mv 2010-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-46702010000100005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP
publisher.none.fl_str_mv Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP
dc.source.none.fl_str_mv Eclética Química v.35 n.1 2010
reponame:Eclética Química
instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Eclética Química
collection Eclética Química
repository.name.fl_str_mv Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
repository.mail.fl_str_mv ecletica@ctrlk.com.br||ecletica@iq.unesp.br
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