Spot-test identification and rapid quantitative sequential analysis of dipyrone
Autor(a) principal: | |
---|---|
Data de Publicação: | 2010 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Eclética Química |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005 |
Resumo: | A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1. |
id |
UNESP-29_dee6e41ec67aa0fb4ca67d993cf8b18a |
---|---|
oai_identifier_str |
oai:scielo:S0100-46702010000100005 |
network_acronym_str |
UNESP-29 |
network_name_str |
Eclética Química |
repository_id_str |
|
spelling |
Spot-test identification and rapid quantitative sequential analysis of dipyronedipyronespot-testanalysisqualitativequantitativeA qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1.Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005Eclética Química v.35 n.1 2010reponame:Eclética Químicainstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESP10.1590/S0100-46702010000100005info:eu-repo/semantics/openAccessTubino,M.Biondo,A. C.Vila,M. M. D. C.Pezza,L.Pezza,H. R.eng2010-06-09T00:00:00Zoai:scielo:S0100-46702010000100005Revistahttp://revista.iq.unesp.br/ojs/index.php/ecletica/PUBhttps://revista.iq.unesp.br/ojs/index.php/ecletica/oaiecletica@ctrlk.com.br||ecletica@iq.unesp.br1678-46181678-4618opendoar:2010-06-09T00:00Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)false |
dc.title.none.fl_str_mv |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
title |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
spellingShingle |
Spot-test identification and rapid quantitative sequential analysis of dipyrone Tubino,M. dipyrone spot-test analysis qualitative quantitative |
title_short |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
title_full |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
title_fullStr |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
title_full_unstemmed |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
title_sort |
Spot-test identification and rapid quantitative sequential analysis of dipyrone |
author |
Tubino,M. |
author_facet |
Tubino,M. Biondo,A. C. Vila,M. M. D. C. Pezza,L. Pezza,H. R. |
author_role |
author |
author2 |
Biondo,A. C. Vila,M. M. D. C. Pezza,L. Pezza,H. R. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Tubino,M. Biondo,A. C. Vila,M. M. D. C. Pezza,L. Pezza,H. R. |
dc.subject.por.fl_str_mv |
dipyrone spot-test analysis qualitative quantitative |
topic |
dipyrone spot-test analysis qualitative quantitative |
description |
A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student's t and the F tests. Considering the concentration in a 100 µL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702010000100005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-46702010000100005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP |
publisher.none.fl_str_mv |
Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP |
dc.source.none.fl_str_mv |
Eclética Química v.35 n.1 2010 reponame:Eclética Química instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Eclética Química |
collection |
Eclética Química |
repository.name.fl_str_mv |
Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
repository.mail.fl_str_mv |
ecletica@ctrlk.com.br||ecletica@iq.unesp.br |
_version_ |
1754734618568818688 |