Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/28029 |
Resumo: | Cutaneous mucosal leishmaniasis (LM) is a chronic infection that affects the upper respiratory tract and/or buccal mucosa and is caused by Leishmania protozoan parasites. A 71-year-old male smoker received dental care at the Stomatology Service of the Hospital Metropolitano Odilon Behrens (HMOB), after various appointments with medical specialists. He presented granulomatous and erythematous lesions on the skin of the nose, on upper lip mucosa, and along the entire soft palate and uvula, as well as the destruction of the nasal septum. Due to the suspicion of leishmaniasis, an incisional biopsy was performed. Histopathological examination was performed; however, polymerase chain reaction (PCR) and immunofluorescence were necessary to confirm the diagnosis of LM. The patient was treated with 27 doses of liposomal amphotericin B 20mg / Sbv / kg / day. Due to the lack of improvement, the patient was again hospitalized, and the medication was repeated adding Fluconazol 150mg, to which the patient showed significant improvement. The present case report shows an infectious lesion that is unusual in dental practice and its approach. The description of the characteristics and management, together with the pathological process, were presented. |
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Clinical manifestations of exuberant leishmaniasis mucocutaneous: case reportManifestaciones clínicas de leishmaniasis mucocutánea exuberante: reporte de casoManifestações clínicas de leishmaniose mucocutânea exuberante: relato de casoMucocutaneous leishmaniasisLeishmaniaCommunicable diseasesHealth teaching.Leishmaniose mucocutâneaLeishmaniaDoenças transmissíveisEnsino em saúde.Leishmaniasis mucocutáneaLeishmaniaEnfermedades transmisiblesEnseñanza para la salud.Cutaneous mucosal leishmaniasis (LM) is a chronic infection that affects the upper respiratory tract and/or buccal mucosa and is caused by Leishmania protozoan parasites. A 71-year-old male smoker received dental care at the Stomatology Service of the Hospital Metropolitano Odilon Behrens (HMOB), after various appointments with medical specialists. He presented granulomatous and erythematous lesions on the skin of the nose, on upper lip mucosa, and along the entire soft palate and uvula, as well as the destruction of the nasal septum. Due to the suspicion of leishmaniasis, an incisional biopsy was performed. Histopathological examination was performed; however, polymerase chain reaction (PCR) and immunofluorescence were necessary to confirm the diagnosis of LM. The patient was treated with 27 doses of liposomal amphotericin B 20mg / Sbv / kg / day. Due to the lack of improvement, the patient was again hospitalized, and the medication was repeated adding Fluconazol 150mg, to which the patient showed significant improvement. The present case report shows an infectious lesion that is unusual in dental practice and its approach. The description of the characteristics and management, together with the pathological process, were presented.La leishmaniasis mucocutánea (LM) es una infección crónica que afecta el tracto respiratorio superior y/o la mucosa oral y es causada por protozoos de la especie Leishmania. Varón de 71 años, fumador, recibió atención odontológica en el Servicio de Estomatología del Hospital Metropolitano Odilon Behrens (HMOB) luego de varias consultas con médicos especialistas. Presentaba lesiones granulomatosas y eritematosas en la piel de la nariz, mucosa del labio superior y en todo el paladar blando y úvula, además de destrucción del tabique nasal. Ante la sospecha de leishmaniosis se realizó biopsia incisional. Se realizó examen histopatológico, sin embargo, fue necesaria la reacción en cadena de la polimerasa (PCR) y la inmunofluorescencia para confirmar el diagnóstico de LM. El paciente fue tratado con 27 dosis de anfotericina B liposomal a razón de 20 mg/sbv/kg/día. Ante la falta de mejoría, el paciente fue hospitalizado nuevamente, se repitió la medicación y se añadió Fluconazol 150 mg. Entonces el paciente mostró una mejoría significativa. El presente reporte de caso muestra una lesión infecciosa poco común en la práctica odontológica y su abordaje. Se presentó la descripción de las características y manejo, junto con el proceso patológico.A leishmaniose mucocutânea (LM) é uma infecção crônica que acomete o trato respiratório superior e/ ou mucosa bucal e é causada por protozoários da espécie Leishmania. Um homem de 71 anos, fumante, recebeu atendimento odontológico no Serviço de Estomatologia do Hospital Metropolitano Odilon Behrens (HMOB) após várias consultas com médicos especialistas. Apresentava lesões granulomatosas e eritematosas na pele do nariz, mucosa do lábio superior e em todo o palato mole e úvula, além de destruição do septo nasal. Devido à suspeita de leishmaniose, foi realizada biópsia incisional. O exame histopatológico foi realizado, entretanto, a reação em cadeia da polimerase (PCR) e a imunofluorescência foram necessárias para confirmar o diagnóstico de LM. O paciente foi tratado com 27 doses de anfotericina B lipossômica a 20 mg/sbv/kg/dia. Devido à ausência de melhora, o paciente foi novamente internado, sendo repetida a medicação e acrescentando Fluconazol 150 mg. Então o paciente apresentou melhora significativa. O presente relato de caso mostra uma lesão infecciosa incomum na prática odontológica e a sua abordagem. A descrição das características e manejo, juntamente com o processo patológico foram apresentados.Research, Society and Development2022-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2802910.33448/rsd-v11i5.28029Research, Society and Development; Vol. 11 No. 5; e11311528029Research, Society and Development; Vol. 11 Núm. 5; e11311528029Research, Society and Development; v. 11 n. 5; e113115280292525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/28029/24380Copyright (c) 2022 Clebson Pereira Abreu; Fernanda Luiza Araújo de Lima Castro; Sérgio Henrique Benfenatti Botelho; Henrique Bemfica de Faria Freitas; Felipe Paiva Fonseca; Júlio César Tanos Lacerda; Renata Gonçalves Resendehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAbreu, Clebson PereiraCastro, Fernanda Luiza Araújo de Lima Botelho, Sérgio Henrique BenfenattiFreitas, Henrique Bemfica de FariaFonseca, Felipe Paiva Lacerda, Júlio César TanosResende, Renata Gonçalves 2022-04-17T18:18:56Zoai:ojs.pkp.sfu.ca:article/28029Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:45:34.791853Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report Manifestaciones clínicas de leishmaniasis mucocutánea exuberante: reporte de caso Manifestações clínicas de leishmaniose mucocutânea exuberante: relato de caso |
title |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report |
spellingShingle |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report Abreu, Clebson Pereira Mucocutaneous leishmaniasis Leishmania Communicable diseases Health teaching. Leishmaniose mucocutânea Leishmania Doenças transmissíveis Ensino em saúde. Leishmaniasis mucocutánea Leishmania Enfermedades transmisibles Enseñanza para la salud. |
title_short |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report |
title_full |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report |
title_fullStr |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report |
title_full_unstemmed |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report |
title_sort |
Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report |
author |
Abreu, Clebson Pereira |
author_facet |
Abreu, Clebson Pereira Castro, Fernanda Luiza Araújo de Lima Botelho, Sérgio Henrique Benfenatti Freitas, Henrique Bemfica de Faria Fonseca, Felipe Paiva Lacerda, Júlio César Tanos Resende, Renata Gonçalves |
author_role |
author |
author2 |
Castro, Fernanda Luiza Araújo de Lima Botelho, Sérgio Henrique Benfenatti Freitas, Henrique Bemfica de Faria Fonseca, Felipe Paiva Lacerda, Júlio César Tanos Resende, Renata Gonçalves |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Abreu, Clebson Pereira Castro, Fernanda Luiza Araújo de Lima Botelho, Sérgio Henrique Benfenatti Freitas, Henrique Bemfica de Faria Fonseca, Felipe Paiva Lacerda, Júlio César Tanos Resende, Renata Gonçalves |
dc.subject.por.fl_str_mv |
Mucocutaneous leishmaniasis Leishmania Communicable diseases Health teaching. Leishmaniose mucocutânea Leishmania Doenças transmissíveis Ensino em saúde. Leishmaniasis mucocutánea Leishmania Enfermedades transmisibles Enseñanza para la salud. |
topic |
Mucocutaneous leishmaniasis Leishmania Communicable diseases Health teaching. Leishmaniose mucocutânea Leishmania Doenças transmissíveis Ensino em saúde. Leishmaniasis mucocutánea Leishmania Enfermedades transmisibles Enseñanza para la salud. |
description |
Cutaneous mucosal leishmaniasis (LM) is a chronic infection that affects the upper respiratory tract and/or buccal mucosa and is caused by Leishmania protozoan parasites. A 71-year-old male smoker received dental care at the Stomatology Service of the Hospital Metropolitano Odilon Behrens (HMOB), after various appointments with medical specialists. He presented granulomatous and erythematous lesions on the skin of the nose, on upper lip mucosa, and along the entire soft palate and uvula, as well as the destruction of the nasal septum. Due to the suspicion of leishmaniasis, an incisional biopsy was performed. Histopathological examination was performed; however, polymerase chain reaction (PCR) and immunofluorescence were necessary to confirm the diagnosis of LM. The patient was treated with 27 doses of liposomal amphotericin B 20mg / Sbv / kg / day. Due to the lack of improvement, the patient was again hospitalized, and the medication was repeated adding Fluconazol 150mg, to which the patient showed significant improvement. The present case report shows an infectious lesion that is unusual in dental practice and its approach. The description of the characteristics and management, together with the pathological process, were presented. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/28029 10.33448/rsd-v11i5.28029 |
url |
https://rsdjournal.org/index.php/rsd/article/view/28029 |
identifier_str_mv |
10.33448/rsd-v11i5.28029 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/28029/24380 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 5; e11311528029 Research, Society and Development; Vol. 11 Núm. 5; e11311528029 Research, Society and Development; v. 11 n. 5; e11311528029 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052709009883136 |