Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report

Detalhes bibliográficos
Autor(a) principal: Abreu, Clebson Pereira
Data de Publicação: 2022
Outros Autores: Castro, Fernanda Luiza Araújo de Lima, Botelho, Sérgio Henrique Benfenatti, Freitas, Henrique Bemfica de Faria, Fonseca, Felipe Paiva, Lacerda, Júlio César Tanos, Resende, Renata Gonçalves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/28029
Resumo: Cutaneous mucosal leishmaniasis (LM) is a chronic infection that affects the upper respiratory tract and/or buccal mucosa and is caused by Leishmania protozoan parasites. A 71-year-old male smoker received dental care at the Stomatology Service of the Hospital Metropolitano Odilon Behrens (HMOB), after various appointments with medical specialists. He presented granulomatous and erythematous lesions on the skin of the nose, on upper lip mucosa, and along the entire soft palate and uvula, as well as the destruction of the nasal septum. Due to the suspicion of leishmaniasis, an incisional biopsy was performed. Histopathological examination was performed; however, polymerase chain reaction (PCR) and immunofluorescence were necessary to confirm the diagnosis of LM. The patient was treated with 27 doses of liposomal amphotericin B 20mg / Sbv / kg / day. Due to the lack of improvement, the patient was again hospitalized, and the medication was repeated adding Fluconazol 150mg, to which the patient showed significant improvement. The present case report shows an infectious lesion that is unusual in dental practice and its approach. The description of the characteristics and management, together with the pathological process, were presented.
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spelling Clinical manifestations of exuberant leishmaniasis mucocutaneous: case reportManifestaciones clínicas de leishmaniasis mucocutánea exuberante: reporte de casoManifestações clínicas de leishmaniose mucocutânea exuberante: relato de casoMucocutaneous leishmaniasisLeishmaniaCommunicable diseasesHealth teaching.Leishmaniose mucocutâneaLeishmaniaDoenças transmissíveisEnsino em saúde.Leishmaniasis mucocutáneaLeishmaniaEnfermedades transmisiblesEnseñanza para la salud.Cutaneous mucosal leishmaniasis (LM) is a chronic infection that affects the upper respiratory tract and/or buccal mucosa and is caused by Leishmania protozoan parasites. A 71-year-old male smoker received dental care at the Stomatology Service of the Hospital Metropolitano Odilon Behrens (HMOB), after various appointments with medical specialists. He presented granulomatous and erythematous lesions on the skin of the nose, on upper lip mucosa, and along the entire soft palate and uvula, as well as the destruction of the nasal septum. Due to the suspicion of leishmaniasis, an incisional biopsy was performed. Histopathological examination was performed; however, polymerase chain reaction (PCR) and immunofluorescence were necessary to confirm the diagnosis of LM. The patient was treated with 27 doses of liposomal amphotericin B 20mg / Sbv / kg / day. Due to the lack of improvement, the patient was again hospitalized, and the medication was repeated adding Fluconazol 150mg, to which the patient showed significant improvement. The present case report shows an infectious lesion that is unusual in dental practice and its approach. The description of the characteristics and management, together with the pathological process, were presented.La leishmaniasis mucocutánea (LM) es una infección crónica que afecta el tracto respiratorio superior y/o la mucosa oral y es causada por protozoos de la especie Leishmania. Varón de 71 años, fumador, recibió atención odontológica en el Servicio de Estomatología del Hospital Metropolitano Odilon Behrens (HMOB) luego de varias consultas con médicos especialistas. Presentaba lesiones granulomatosas y eritematosas en la piel de la nariz, mucosa del labio superior y en todo el paladar blando y úvula, además de destrucción del tabique nasal. Ante la sospecha de leishmaniosis se realizó biopsia incisional. Se realizó examen histopatológico, sin embargo, fue necesaria la reacción en cadena de la polimerasa (PCR) y la inmunofluorescencia para confirmar el diagnóstico de LM. El paciente fue tratado con 27 dosis de anfotericina B liposomal a razón de 20 mg/sbv/kg/día. Ante la falta de mejoría, el paciente fue hospitalizado nuevamente, se repitió la medicación y se añadió Fluconazol 150 mg. Entonces el paciente mostró una mejoría significativa. El presente reporte de caso muestra una lesión infecciosa poco común en la práctica odontológica y su abordaje. Se presentó la descripción de las características y manejo, junto con el proceso patológico.A leishmaniose mucocutânea (LM) é uma infecção crônica que acomete o trato respiratório superior e/ ou mucosa bucal e é causada por protozoários da espécie Leishmania. Um homem de 71 anos, fumante, recebeu atendimento odontológico no Serviço de Estomatologia do Hospital Metropolitano Odilon Behrens (HMOB) após várias consultas com médicos especialistas. Apresentava lesões granulomatosas e eritematosas na pele do nariz, mucosa do lábio superior e em todo o palato mole e úvula, além de destruição do septo nasal. Devido à suspeita de leishmaniose, foi realizada biópsia incisional. O exame histopatológico foi realizado, entretanto, a reação em cadeia da polimerase (PCR) e a imunofluorescência foram necessárias para confirmar o diagnóstico de LM. O paciente foi tratado com 27 doses de anfotericina B lipossômica a 20 mg/sbv/kg/dia. Devido à ausência de melhora, o paciente foi novamente internado, sendo repetida a medicação e acrescentando Fluconazol 150 mg. Então o paciente apresentou melhora significativa. O presente relato de caso mostra uma lesão infecciosa incomum na prática odontológica e a sua abordagem. A descrição das características e manejo, juntamente com o processo patológico foram apresentados.Research, Society and Development2022-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2802910.33448/rsd-v11i5.28029Research, Society and Development; Vol. 11 No. 5; e11311528029Research, Society and Development; Vol. 11 Núm. 5; e11311528029Research, Society and Development; v. 11 n. 5; e113115280292525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/28029/24380Copyright (c) 2022 Clebson Pereira Abreu; Fernanda Luiza Araújo de Lima Castro; Sérgio Henrique Benfenatti Botelho; Henrique Bemfica de Faria Freitas; Felipe Paiva Fonseca; Júlio César Tanos Lacerda; Renata Gonçalves Resendehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAbreu, Clebson PereiraCastro, Fernanda Luiza Araújo de Lima Botelho, Sérgio Henrique BenfenattiFreitas, Henrique Bemfica de FariaFonseca, Felipe Paiva Lacerda, Júlio César TanosResende, Renata Gonçalves 2022-04-17T18:18:56Zoai:ojs.pkp.sfu.ca:article/28029Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:45:34.791853Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
Manifestaciones clínicas de leishmaniasis mucocutánea exuberante: reporte de caso
Manifestações clínicas de leishmaniose mucocutânea exuberante: relato de caso
title Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
spellingShingle Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
Abreu, Clebson Pereira
Mucocutaneous leishmaniasis
Leishmania
Communicable diseases
Health teaching.
Leishmaniose mucocutânea
Leishmania
Doenças transmissíveis
Ensino em saúde.
Leishmaniasis mucocutánea
Leishmania
Enfermedades transmisibles
Enseñanza para la salud.
title_short Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
title_full Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
title_fullStr Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
title_full_unstemmed Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
title_sort Clinical manifestations of exuberant leishmaniasis mucocutaneous: case report
author Abreu, Clebson Pereira
author_facet Abreu, Clebson Pereira
Castro, Fernanda Luiza Araújo de Lima
Botelho, Sérgio Henrique Benfenatti
Freitas, Henrique Bemfica de Faria
Fonseca, Felipe Paiva
Lacerda, Júlio César Tanos
Resende, Renata Gonçalves
author_role author
author2 Castro, Fernanda Luiza Araújo de Lima
Botelho, Sérgio Henrique Benfenatti
Freitas, Henrique Bemfica de Faria
Fonseca, Felipe Paiva
Lacerda, Júlio César Tanos
Resende, Renata Gonçalves
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Abreu, Clebson Pereira
Castro, Fernanda Luiza Araújo de Lima
Botelho, Sérgio Henrique Benfenatti
Freitas, Henrique Bemfica de Faria
Fonseca, Felipe Paiva
Lacerda, Júlio César Tanos
Resende, Renata Gonçalves
dc.subject.por.fl_str_mv Mucocutaneous leishmaniasis
Leishmania
Communicable diseases
Health teaching.
Leishmaniose mucocutânea
Leishmania
Doenças transmissíveis
Ensino em saúde.
Leishmaniasis mucocutánea
Leishmania
Enfermedades transmisibles
Enseñanza para la salud.
topic Mucocutaneous leishmaniasis
Leishmania
Communicable diseases
Health teaching.
Leishmaniose mucocutânea
Leishmania
Doenças transmissíveis
Ensino em saúde.
Leishmaniasis mucocutánea
Leishmania
Enfermedades transmisibles
Enseñanza para la salud.
description Cutaneous mucosal leishmaniasis (LM) is a chronic infection that affects the upper respiratory tract and/or buccal mucosa and is caused by Leishmania protozoan parasites. A 71-year-old male smoker received dental care at the Stomatology Service of the Hospital Metropolitano Odilon Behrens (HMOB), after various appointments with medical specialists. He presented granulomatous and erythematous lesions on the skin of the nose, on upper lip mucosa, and along the entire soft palate and uvula, as well as the destruction of the nasal septum. Due to the suspicion of leishmaniasis, an incisional biopsy was performed. Histopathological examination was performed; however, polymerase chain reaction (PCR) and immunofluorescence were necessary to confirm the diagnosis of LM. The patient was treated with 27 doses of liposomal amphotericin B 20mg / Sbv / kg / day. Due to the lack of improvement, the patient was again hospitalized, and the medication was repeated adding Fluconazol 150mg, to which the patient showed significant improvement. The present case report shows an infectious lesion that is unusual in dental practice and its approach. The description of the characteristics and management, together with the pathological process, were presented.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/28029
10.33448/rsd-v11i5.28029
url https://rsdjournal.org/index.php/rsd/article/view/28029
identifier_str_mv 10.33448/rsd-v11i5.28029
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/28029/24380
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 5; e11311528029
Research, Society and Development; Vol. 11 Núm. 5; e11311528029
Research, Society and Development; v. 11 n. 5; e11311528029
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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