Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/29209 |
Resumo: | The central giant cell lesion of the maxillary is a rare intraosseous lesion, which presents a variable clinical and radiographic behavior. Its conventional treatment consists of surgical removal, however there are several associated factors, such as the patient's age, extension and behavior of the lesion that are taken. into account in choosing the appropriate treatment. The aim of the study is to report a clinical case of LCCG in the posterior region of the mandible, in a 35-year-old female patient, complaining of hardened increase in volume and tooth mobility of the elements close to the lesion, where an intralesional injection of 8mg of corticosteroids was do per weekly, fortnightly and monthly sessions for 6 months, after that, enucleation with curettage and total removal of the lesion, and extraction of elements affected and compromised by caries and periodontal lesions were performed. Central giant cell lesion requires a precise diagnosis, in order to select the appropriate treatment, taking into account the characteristics of the lesion in each patient. In aggressive lesions, the treatment is always surgical due to the higher success rate. |
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Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report Corticoterapia como tratamiento adyuvante de Lesión de Células Gigantes Centrales grandes: reporte de casoCorticoterapia como tratamento adjuvante de Lesão Central de Células Gigantes de grandes dimensões: relato de casoGiant Cell GranulomaCorticosteroidsOral surgeryJaw.Granuloma de células gigantesCorticosteroidesCirugía oralMandíbula.Granuloma de Células GigantesCorticoesteroidesCirurgia bucalMandíbula.The central giant cell lesion of the maxillary is a rare intraosseous lesion, which presents a variable clinical and radiographic behavior. Its conventional treatment consists of surgical removal, however there are several associated factors, such as the patient's age, extension and behavior of the lesion that are taken. into account in choosing the appropriate treatment. The aim of the study is to report a clinical case of LCCG in the posterior region of the mandible, in a 35-year-old female patient, complaining of hardened increase in volume and tooth mobility of the elements close to the lesion, where an intralesional injection of 8mg of corticosteroids was do per weekly, fortnightly and monthly sessions for 6 months, after that, enucleation with curettage and total removal of the lesion, and extraction of elements affected and compromised by caries and periodontal lesions were performed. Central giant cell lesion requires a precise diagnosis, in order to select the appropriate treatment, taking into account the characteristics of the lesion in each patient. In aggressive lesions, the treatment is always surgical due to the higher success rate.La lesión central de células gigantes del maxilar es una lesión intraósea rara, la cual presenta un comportamiento clínico y radiográfico variable. Su tratamiento convencional consiste en la extirpación quirúrgica, sin embargo existen varios factores asociados, como la edad del paciente, extensión y comportamiento de la lesión. que se tienen en cuenta a la hora de elegir el tratamiento adecuado. El objetivo del estudio es reportar un caso clínico de LCCG en la región posterior de la mandíbula, en una paciente de 35 años, que se queja de aumento endurecido de volumen y movilidad dentaria de los elementos cercanos a la lesión, donde un inyección intralesional de 8 mg de corticoides por sesiones semanales, quincenales y mensuales durante 6 meses, posteriormente se realizó enucleación con curetaje y extirpación total de la lesión y extracción de los elementos afectados y comprometidos por caries y lesiones periodontales. La lesión central de células gigantes requiere un diagnóstico preciso, para poder seleccionar el tratamiento adecuado, teniendo en cuenta las características de la lesión en cada paciente. En las lesiones agresivas el tratamiento es siempre quirúrgico por la mayor tasa de éxito.A lesão central de células gigantes (LCCG) dos maxilares é uma lesão intra-óssea rara, que apresenta comportamento clínico e radiográfico variável. Seu tratamento convencional consiste na remoção cirúrgica, entretanto há vários fatores associados, como a idade do paciente, extensão e comportamento da lesão que são considerados na escolha do tratamento apropriado. O objetivo do estudo é relatar um caso de LCCG tratado com corticoterapia e excisão cirúrgica. Por cerca de 6 meses foi instituído um protocolo de injeções intra-lesionais com corticoides para regressão da lesão e também para facilitar o manejo cirúrgico final e evitar recidivas. Ambas as terapias apresentaram resultados satisfatórios e a paciente evoluiu assintomática e sem queixas pós-operatórias. Os achados radiográficos de 6 meses de acompanhamento evidenciaram neoformação óssea e também não foram observadas recidivas clinicamente. É evidente que a LCCG requer um diagnóstico preciso, a fim de selecionar o tratamento adequado, a depender das características de cada caso. Em lesões agressivas o tratamento é sempre cirúrgico pela maior taxa de sucesso.Research, Society and Development2022-04-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2920910.33448/rsd-v11i6.29209Research, Society and Development; Vol. 11 No. 6; e28011629209Research, Society and Development; Vol. 11 Núm. 6; e28011629209Research, Society and Development; v. 11 n. 6; e280116292092525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/29209/25215Copyright (c) 2022 Isabely Evelyn Andrade do Nascimento; Júlio Maciel Monteiro; Rafael Lucas Guilhermino Jacinto ; Geovanna de Castro Bizarria; Maelly Vicente Lôbo; Taysnara Ismaeley de Andrade; Kayo Costa Alves; Alexandre Freitas de Santana; Belmino Carlos Amaral Torreshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessNascimento, Isabely Evelyn Andrade do Monteiro, Júlio Maciel Jacinto , Rafael Lucas Guilhermino Bizarria, Geovanna de Castro Lôbo, Maelly Vicente Andrade, Taysnara Ismaeley de Alves, Kayo Costa Santana, Alexandre Freitas de Torres, Belmino Carlos Amaral 2022-05-13T18:04:10Zoai:ojs.pkp.sfu.ca:article/29209Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:46:20.969531Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report Corticoterapia como tratamiento adyuvante de Lesión de Células Gigantes Centrales grandes: reporte de caso Corticoterapia como tratamento adjuvante de Lesão Central de Células Gigantes de grandes dimensões: relato de caso |
title |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report |
spellingShingle |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report Nascimento, Isabely Evelyn Andrade do Giant Cell Granuloma Corticosteroids Oral surgery Jaw. Granuloma de células gigantes Corticosteroides Cirugía oral Mandíbula. Granuloma de Células Gigantes Corticoesteroides Cirurgia bucal Mandíbula. |
title_short |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report |
title_full |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report |
title_fullStr |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report |
title_full_unstemmed |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report |
title_sort |
Corticosteroid therapy as adjuvant treatment of large Central Giant Cell Lesion: case report |
author |
Nascimento, Isabely Evelyn Andrade do |
author_facet |
Nascimento, Isabely Evelyn Andrade do Monteiro, Júlio Maciel Jacinto , Rafael Lucas Guilhermino Bizarria, Geovanna de Castro Lôbo, Maelly Vicente Andrade, Taysnara Ismaeley de Alves, Kayo Costa Santana, Alexandre Freitas de Torres, Belmino Carlos Amaral |
author_role |
author |
author2 |
Monteiro, Júlio Maciel Jacinto , Rafael Lucas Guilhermino Bizarria, Geovanna de Castro Lôbo, Maelly Vicente Andrade, Taysnara Ismaeley de Alves, Kayo Costa Santana, Alexandre Freitas de Torres, Belmino Carlos Amaral |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Nascimento, Isabely Evelyn Andrade do Monteiro, Júlio Maciel Jacinto , Rafael Lucas Guilhermino Bizarria, Geovanna de Castro Lôbo, Maelly Vicente Andrade, Taysnara Ismaeley de Alves, Kayo Costa Santana, Alexandre Freitas de Torres, Belmino Carlos Amaral |
dc.subject.por.fl_str_mv |
Giant Cell Granuloma Corticosteroids Oral surgery Jaw. Granuloma de células gigantes Corticosteroides Cirugía oral Mandíbula. Granuloma de Células Gigantes Corticoesteroides Cirurgia bucal Mandíbula. |
topic |
Giant Cell Granuloma Corticosteroids Oral surgery Jaw. Granuloma de células gigantes Corticosteroides Cirugía oral Mandíbula. Granuloma de Células Gigantes Corticoesteroides Cirurgia bucal Mandíbula. |
description |
The central giant cell lesion of the maxillary is a rare intraosseous lesion, which presents a variable clinical and radiographic behavior. Its conventional treatment consists of surgical removal, however there are several associated factors, such as the patient's age, extension and behavior of the lesion that are taken. into account in choosing the appropriate treatment. The aim of the study is to report a clinical case of LCCG in the posterior region of the mandible, in a 35-year-old female patient, complaining of hardened increase in volume and tooth mobility of the elements close to the lesion, where an intralesional injection of 8mg of corticosteroids was do per weekly, fortnightly and monthly sessions for 6 months, after that, enucleation with curettage and total removal of the lesion, and extraction of elements affected and compromised by caries and periodontal lesions were performed. Central giant cell lesion requires a precise diagnosis, in order to select the appropriate treatment, taking into account the characteristics of the lesion in each patient. In aggressive lesions, the treatment is always surgical due to the higher success rate. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-28 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/29209 10.33448/rsd-v11i6.29209 |
url |
https://rsdjournal.org/index.php/rsd/article/view/29209 |
identifier_str_mv |
10.33448/rsd-v11i6.29209 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/29209/25215 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 6; e28011629209 Research, Society and Development; Vol. 11 Núm. 6; e28011629209 Research, Society and Development; v. 11 n. 6; e28011629209 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052811838488576 |