Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/33353 |
Resumo: | In recent years, obtaining protein hydrolysates and peptides from food proteins has been widely studied in order to better understand not only their nutritional and functional properties, but also the possibility of their use as ingredients in functional foods. It is known that many dietary proteins have, in their primary structure, peptide sequences that, when released, can be absorbed by enterocytes and modulate specific physiological functions, in addition to providing essential amino acids and contributing to energy metabolism. Therefore, this review aims to carry out a systematic review to assess the effectiveness of these bioactive compounds in controlling blood pressure in rats. In addition, the methodological quality of the published articles was evaluated. Searches in Scopus, ScienceDirect, ISI Web of Science and PubMed databases were focused on studies on the use of hydrolysates and peptides obtained from the enzymatic hydrolysis of various chicken tissues in rats. It was possible to verify that the positive antihypertensive effects were mainly dependent on the enzymatic conditions and enzymatic hydrolysis and the monitoring of vital organ functions is essential for the regulation of blood pressure. Due to their effectiveness and low cost, chicken protein hydrolysates could be an interesting alternative for biotechnology applications. Administration of hydrolysates and peptides derived from chicken proteins to spontaneously hypertensive rats (SHR) exhibit potential antihypertensive activity with likely cardiac protective effects against target organ damage. |
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Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in ratsHidrolizados y péptidos bioactivos generados a partir de la hidrólisis de proteína de pollo: Una revisión sistemática de los efectos antihipertensivos en ratasHidrolisados e peptídeos bioativos gerados a partir da hidrólise de proteínas de frango: Uma revisão sistemática dos efeitos anti-hipertensivos em ratosHidrolisados proteicosPeptídeos bioativosProteína de frangoAtividade anti-hipertensivaHidrólise enzimáticaRatos espontaneamente hipertensos.Protein hydrolysatesBioactive peptidesChicken proteinAntihypertensive activityEnzymatic hydrolysisSpontaneously hypertensive rats.Hidrolizados de proteínaPéptidos bioactivosProteína de polloActividad anti-hipertensivaHidrólisis enzimáticaRatas espontáneamente hipertensas.In recent years, obtaining protein hydrolysates and peptides from food proteins has been widely studied in order to better understand not only their nutritional and functional properties, but also the possibility of their use as ingredients in functional foods. It is known that many dietary proteins have, in their primary structure, peptide sequences that, when released, can be absorbed by enterocytes and modulate specific physiological functions, in addition to providing essential amino acids and contributing to energy metabolism. Therefore, this review aims to carry out a systematic review to assess the effectiveness of these bioactive compounds in controlling blood pressure in rats. In addition, the methodological quality of the published articles was evaluated. Searches in Scopus, ScienceDirect, ISI Web of Science and PubMed databases were focused on studies on the use of hydrolysates and peptides obtained from the enzymatic hydrolysis of various chicken tissues in rats. It was possible to verify that the positive antihypertensive effects were mainly dependent on the enzymatic conditions and enzymatic hydrolysis and the monitoring of vital organ functions is essential for the regulation of blood pressure. Due to their effectiveness and low cost, chicken protein hydrolysates could be an interesting alternative for biotechnology applications. Administration of hydrolysates and peptides derived from chicken proteins to spontaneously hypertensive rats (SHR) exhibit potential antihypertensive activity with likely cardiac protective effects against target organ damage.En los últimos años se ha estudiado ampliamente la obtención de hidrolizados de proteínas y péptidos a partir de proteínas alimentarias con el fin de conocer mejor no solo sus propiedades nutricionales y funcionales, sino también la posibilidad de su uso como ingredientes en alimentos funcionales. Se sabe que muchas proteínas de la dieta tienen, en su estructura primaria, secuencias peptídicas que, al ser liberadas, pueden ser absorbidas por los enterocitos y modular funciones fisiológicas específicas, además de aportar aminoácidos esenciales y contribuir al metabolismo energético. Por lo tanto, esta revisión tiene como objetivo realizar una revisión sistemática para evaluar la efectividad de estos compuestos bioactivos en el control de la presión arterial en ratas. Además, se evaluó la calidad metodológica de los artículos publicados. Las búsquedas en las bases de datos Scopus, ScienceDirect, ISI Web of Science y PubMed se centraron en estudios sobre el uso de hidrolizados y péptidos obtenidos de la hidrólisis enzimática de diversos tejidos de pollo en ratas. Fue posible verificar que los efectos antihipertensivos positivos dependían principalmente de las condiciones enzimáticas y de la hidrólisis enzimática y el monitoreo de las funciones de los órganos vitales es esencial para la regulación de la presión arterial. Debido a su efectividad y bajo costo, los hidrolizados de proteína de pollo podrían ser una alternativa interesante para aplicaciones biotecnológicas. La administración de hidrolizados y péptidos derivados de proteínas de pollo a ratas espontáneamente hipertensas (SHR, por sus siglas en inglés) muestra una potencial actividad antihipertensiva con probables efectos protectores cardíacos contra el daño a los órganos diana.Nos últimos anos, a obtenção de hidrolisados proteicos e peptídeos a partir de proteínas alimentares tem sido amplamente estudada com o intuito de melhor compreender não apenas suas propriedades nutricionais e funcionais, mas também a possibilidade de sua utilização como ingredientes em alimentos funcionais. Sabe-se que muitas proteínas da dieta possuem, em sua estrutura primária, sequências peptídicas que, ao serem liberadas, podem ser absorvidas pelos enterócitos e modular funções fisiológicas específicas, além de fornecer aminoácidos essenciais e contribuir para o metabolismo energético. Portanto, esta revisão tem o objetivo de realizar uma revisão sistemática para avaliar a eficácia desses compostos bioativos no controle da pressão arterial em ratos. Além disso, avaliou-se a qualidade metodológica dos artigos publicados. As buscas nas bases de dados Scopus, ScienceDirect, ISI Web of Science e PubMed foram focadas em estudos sobre o uso de hidrolisados e peptídeos obtidos a partir da hidrólise enzimática de diversos tecidos de frango em ratos. Foi possível verificar que os efeitos anti-hipertensivos positivos foram dependentes principalmente das condições enzimáticas e de hidrólise enzimática e o monitoramento das funções dos órgãos vitais é essencial para a regulação da pressão arterial. Devido à sua eficácia e baixo custo, os hidrolisados de proteína de frango podem ser uma alternativa interessante para aplicações biotecnológicas. A administração de hidrolisados e peptídeos derivados de proteínas de frango a ratos espontaneamente hipertensos (SHR) exibe um potencial atividade anti-hipertensiva com prováveis efeitos protetores cardíacos contra danos em órgãos-alvo.Research, Society and Development2022-08-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3335310.33448/rsd-v11i11.33353Research, Society and Development; Vol. 11 No. 11; e181111133353Research, Society and Development; Vol. 11 Núm. 11; e181111133353Research, Society and Development; v. 11 n. 11; e1811111333532525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/33353/28326Copyright (c) 2022 Thiago Santos Araujo; Leandro Paes de Brito; José Manoel Wanderley Duarte Neto; Maria Carolina de Albuquerque Wanderley; Wendell Wagner Campos Albuquerque; Polyanna Nunes Herculano; Lorenzo Pastrana ; Maria Taciana Cavalcanti Vieira Soares ; Ana Lúcia Figueiredo Portohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAraujo, Thiago Santos Brito, Leandro Paes de Duarte Neto, José Manoel WanderleyWanderley, Maria Carolina de Albuquerque Albuquerque, Wendell Wagner Campos Herculano, Polyanna Nunes Pastrana , Lorenzo Soares , Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33353Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:01.922248Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats Hidrolizados y péptidos bioactivos generados a partir de la hidrólisis de proteína de pollo: Una revisión sistemática de los efectos antihipertensivos en ratas Hidrolisados e peptídeos bioativos gerados a partir da hidrólise de proteínas de frango: Uma revisão sistemática dos efeitos anti-hipertensivos em ratos |
| title |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats |
| spellingShingle |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats Araujo, Thiago Santos Hidrolisados proteicos Peptídeos bioativos Proteína de frango Atividade anti-hipertensiva Hidrólise enzimática Ratos espontaneamente hipertensos. Protein hydrolysates Bioactive peptides Chicken protein Antihypertensive activity Enzymatic hydrolysis Spontaneously hypertensive rats. Hidrolizados de proteína Péptidos bioactivos Proteína de pollo Actividad anti-hipertensiva Hidrólisis enzimática Ratas espontáneamente hipertensas. |
| title_short |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats |
| title_full |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats |
| title_fullStr |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats |
| title_full_unstemmed |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats |
| title_sort |
Hydrolysates and bioactive peptides generated from chicken protein hydrolysis: A systematic review of antihypertensive effects in rats |
| author |
Araujo, Thiago Santos |
| author_facet |
Araujo, Thiago Santos Brito, Leandro Paes de Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque Albuquerque, Wendell Wagner Campos Herculano, Polyanna Nunes Pastrana , Lorenzo Soares , Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo |
| author_role |
author |
| author2 |
Brito, Leandro Paes de Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque Albuquerque, Wendell Wagner Campos Herculano, Polyanna Nunes Pastrana , Lorenzo Soares , Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Araujo, Thiago Santos Brito, Leandro Paes de Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque Albuquerque, Wendell Wagner Campos Herculano, Polyanna Nunes Pastrana , Lorenzo Soares , Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo |
| dc.subject.por.fl_str_mv |
Hidrolisados proteicos Peptídeos bioativos Proteína de frango Atividade anti-hipertensiva Hidrólise enzimática Ratos espontaneamente hipertensos. Protein hydrolysates Bioactive peptides Chicken protein Antihypertensive activity Enzymatic hydrolysis Spontaneously hypertensive rats. Hidrolizados de proteína Péptidos bioactivos Proteína de pollo Actividad anti-hipertensiva Hidrólisis enzimática Ratas espontáneamente hipertensas. |
| topic |
Hidrolisados proteicos Peptídeos bioativos Proteína de frango Atividade anti-hipertensiva Hidrólise enzimática Ratos espontaneamente hipertensos. Protein hydrolysates Bioactive peptides Chicken protein Antihypertensive activity Enzymatic hydrolysis Spontaneously hypertensive rats. Hidrolizados de proteína Péptidos bioactivos Proteína de pollo Actividad anti-hipertensiva Hidrólisis enzimática Ratas espontáneamente hipertensas. |
| description |
In recent years, obtaining protein hydrolysates and peptides from food proteins has been widely studied in order to better understand not only their nutritional and functional properties, but also the possibility of their use as ingredients in functional foods. It is known that many dietary proteins have, in their primary structure, peptide sequences that, when released, can be absorbed by enterocytes and modulate specific physiological functions, in addition to providing essential amino acids and contributing to energy metabolism. Therefore, this review aims to carry out a systematic review to assess the effectiveness of these bioactive compounds in controlling blood pressure in rats. In addition, the methodological quality of the published articles was evaluated. Searches in Scopus, ScienceDirect, ISI Web of Science and PubMed databases were focused on studies on the use of hydrolysates and peptides obtained from the enzymatic hydrolysis of various chicken tissues in rats. It was possible to verify that the positive antihypertensive effects were mainly dependent on the enzymatic conditions and enzymatic hydrolysis and the monitoring of vital organ functions is essential for the regulation of blood pressure. Due to their effectiveness and low cost, chicken protein hydrolysates could be an interesting alternative for biotechnology applications. Administration of hydrolysates and peptides derived from chicken proteins to spontaneously hypertensive rats (SHR) exhibit potential antihypertensive activity with likely cardiac protective effects against target organ damage. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-08-19 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/33353 10.33448/rsd-v11i11.33353 |
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https://rsdjournal.org/index.php/rsd/article/view/33353 |
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10.33448/rsd-v11i11.33353 |
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eng |
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eng |
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https://rsdjournal.org/index.php/rsd/article/view/33353/28326 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 11 No. 11; e181111133353 Research, Society and Development; Vol. 11 Núm. 11; e181111133353 Research, Society and Development; v. 11 n. 11; e181111133353 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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