Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/16448 |
Resumo: | This study aimed to evaluate the effect of replacing pregelatinized starch with resistant starch on the metabolism of lipids and carbohydrates in male Wistar rats. 20 male rats were divided into two groups, which received a diet with 9.5% (DAP) and 18.1% (DAR) of resistant starch for 22 days. Weight, feed, and water consumption were analyzed and the concentrations of cholesterol and triglycerides in serum and muscle and hepatic and muscle glycogen were quantified. The data were analyzed by Tukey's test (p>0.05) and box-plot graphs. There were no significant differences in feed and water intake, but the animals in the DAP group showed an increase in weight (51.12g to 55.27g) while those in the DAR group decreased (49.01g to 44.15g). The DAR group showed a decrease in triglycerides, total serum cholesterol (from 125.761 mg/dL to 104.874 mg/dL), and muscle glycogen, but an increase in triglycerides in the gastrocnemius muscle compared to the DAP group (from 0.160 mg/dL to 0.259 mg/dL). These results point to a decrease in the glucose absorption speed in the group of animals with a diet with a higher amount of resistant starch, which may have induced a decrease in the processes of synthesis of triglycerides and cholesterol leading to an increase in catabolism of these substrates by the body, plastic adaptation of muscles for the use of fatty acids in their oxidative metabolism. |
id |
UNIFEI_b466dbe5881cd020d2d99cd740dd2e67 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/16448 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar ratsAlteraciones inducidas por la dieta con diferentes concentraciones de almidón resistente en el metabolismo de carbohidratos y lípidos, en ratas WistarAlterações induzidas pela dieta com diferentes concentrações de amido resistente no metabolismo de carboidratos e de lipídeos, em ratos WistarAlmidón pregelatinizadoDietas experimentalesTriglicéridosGlucógenoColesterol.Amido pré-gelatinizadoDietas experimentaisTriglicerídeosGlicogênioColesterol.Pregelatinized starchExperimental dietsTriglyceridesGlycogenCholesterol.This study aimed to evaluate the effect of replacing pregelatinized starch with resistant starch on the metabolism of lipids and carbohydrates in male Wistar rats. 20 male rats were divided into two groups, which received a diet with 9.5% (DAP) and 18.1% (DAR) of resistant starch for 22 days. Weight, feed, and water consumption were analyzed and the concentrations of cholesterol and triglycerides in serum and muscle and hepatic and muscle glycogen were quantified. The data were analyzed by Tukey's test (p>0.05) and box-plot graphs. There were no significant differences in feed and water intake, but the animals in the DAP group showed an increase in weight (51.12g to 55.27g) while those in the DAR group decreased (49.01g to 44.15g). The DAR group showed a decrease in triglycerides, total serum cholesterol (from 125.761 mg/dL to 104.874 mg/dL), and muscle glycogen, but an increase in triglycerides in the gastrocnemius muscle compared to the DAP group (from 0.160 mg/dL to 0.259 mg/dL). These results point to a decrease in the glucose absorption speed in the group of animals with a diet with a higher amount of resistant starch, which may have induced a decrease in the processes of synthesis of triglycerides and cholesterol leading to an increase in catabolism of these substrates by the body, plastic adaptation of muscles for the use of fatty acids in their oxidative metabolism.Este estudio tuvo como objetivo evaluar el efecto de la sustitución del almidón pregelatinizado por almidón resistente sobre el metabolismo de lípidos y carbohidratos en ratas Wistar macho. Se dividieron 20 ratas macho en dos grupos, los cuales recibieron una dieta con 9.5% (DAP) y 18.1% (DAR) de almidón resistente durante 22 días. Se analizaron el peso, consumo de alimento y agua, y se cuantificaron las concentraciones de colesterol y triglicéridos en el suero y músculo, y el glucógeno hepático y muscular. Los datos fueron analizados mediante la prueba de Tukey (p>0.05) y gráficos de diagrama de cajas. No hubo diferencias significativas en la ingesta de alimento y agua, sin embargo, los animales del grupo DAP mostraron un aumento de peso (51.12g a 55.27g) mientras que los del grupo DAR disminuyeron (49.01g a 44.15g). El grupo DAR mostró una disminución de triglicéridos, colesterol sérico total (de 125.761 mg/dL a 104.874 mg/dL) y glucógeno muscular, pero un aumento de los triglicéridos en el músculo gastrocnemio en comparación con el grupo DAP (de 0.160 mg/dL a 0.259 mg/dL). Estos resultados apuntan a una disminución de la velocidad de absorción de glucosa en el grupo de animales con una dieta con mayor cantidad de almidón resistente, la cual puede haber inducido una disminución en los procesos de síntesis de triglicéridos y colesterol conduciendo a un aumento del catabolismo de estos sustratos por el organismo, y adaptación plástica de los músculos para el uso de ácidos grasos en su metabolismo oxidativo.Este trabalho teve como objetivo avaliar o efeito da substituição do amido pré-gelatinizado por amido resistente no metabolismo de lipídeos e de carboidratos em ratos machos Wistar. 20 ratos machos foram divididos em dois grupos, um grupo recebeu uma dieta com 9,5% (DAP) e o outro grupo com 18,1% (DAR) de amido resistente durante 22 dias. Foram analisados peso, consumo de ração e água, e quantificadas as concentrações de colesterol e de triglicerídeos no soro e no músculo, e de glicogênio hepático e muscular. Os dados foram analisados por teste de Tukey (p>0,05) e gráficos box-plot. Não houve diferenças significativas na ingestão de ração e água, mas os animais do grupo DAP apresentaram aumento de peso (51,12g para 55,27g) enquanto os do grupo DAR diminuíram (49,01g para 44,15g). O grupo DAR apresentou diminuição de triglicérideos, colesterol total no soro (de 125,761 mg/dL para 104,874 mg/dL) e do glicogênio muscular, mas aumento de triglicerídeos no músculo gastrocnêmio em comparação com o grupo DAP (de 0,160 mg/dL para 0,259 mg/dL). Estes resultados apontam para a diminuição na velocidade de absorção da glicose no grupo de animais com dieta com maior quantidade de amido resistente, que pode ter induzido diminuição nos processos de síntese de triglicérideos e de colesterol levando ao aumento do catabolismo destes substratos pelo organismo, e adaptação plástica dos músculos para utilização de ácidos graxos no seu metabolismo oxidativo.Research, Society and Development2021-06-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1644810.33448/rsd-v10i7.16448Research, Society and Development; Vol. 10 No. 7; e18110716448Research, Society and Development; Vol. 10 Núm. 7; e18110716448Research, Society and Development; v. 10 n. 7; e181107164482525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/16448/14677Copyright (c) 2021 Armindo Antonio Alves; Acácio Antônio Pigoso; Yoon Kil Chang; Bruna Lago Tagliapietra; Marcio Schmiele; Pedro Henrique Campelo; Maria Teresa Pedrosa Silva Clericihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAlves, Armindo Antonio Pigoso, Acácio Antônio Chang, Yoon Kil Tagliapietra, Bruna LagoSchmiele, Marcio Campelo, Pedro Henrique Clerici, Maria Teresa Pedrosa Silva 2021-07-18T21:07:03Zoai:ojs.pkp.sfu.ca:article/16448Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:59.847109Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats Alteraciones inducidas por la dieta con diferentes concentraciones de almidón resistente en el metabolismo de carbohidratos y lípidos, en ratas Wistar Alterações induzidas pela dieta com diferentes concentrações de amido resistente no metabolismo de carboidratos e de lipídeos, em ratos Wistar |
title |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats |
spellingShingle |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats Alves, Armindo Antonio Almidón pregelatinizado Dietas experimentales Triglicéridos Glucógeno Colesterol. Amido pré-gelatinizado Dietas experimentais Triglicerídeos Glicogênio Colesterol. Pregelatinized starch Experimental diets Triglycerides Glycogen Cholesterol. |
title_short |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats |
title_full |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats |
title_fullStr |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats |
title_full_unstemmed |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats |
title_sort |
Changes induced by diet with different concentrations of resistant starch in the metabolism of carbohydrates and lipids in Wistar rats |
author |
Alves, Armindo Antonio |
author_facet |
Alves, Armindo Antonio Pigoso, Acácio Antônio Chang, Yoon Kil Tagliapietra, Bruna Lago Schmiele, Marcio Campelo, Pedro Henrique Clerici, Maria Teresa Pedrosa Silva |
author_role |
author |
author2 |
Pigoso, Acácio Antônio Chang, Yoon Kil Tagliapietra, Bruna Lago Schmiele, Marcio Campelo, Pedro Henrique Clerici, Maria Teresa Pedrosa Silva |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Alves, Armindo Antonio Pigoso, Acácio Antônio Chang, Yoon Kil Tagliapietra, Bruna Lago Schmiele, Marcio Campelo, Pedro Henrique Clerici, Maria Teresa Pedrosa Silva |
dc.subject.por.fl_str_mv |
Almidón pregelatinizado Dietas experimentales Triglicéridos Glucógeno Colesterol. Amido pré-gelatinizado Dietas experimentais Triglicerídeos Glicogênio Colesterol. Pregelatinized starch Experimental diets Triglycerides Glycogen Cholesterol. |
topic |
Almidón pregelatinizado Dietas experimentales Triglicéridos Glucógeno Colesterol. Amido pré-gelatinizado Dietas experimentais Triglicerídeos Glicogênio Colesterol. Pregelatinized starch Experimental diets Triglycerides Glycogen Cholesterol. |
description |
This study aimed to evaluate the effect of replacing pregelatinized starch with resistant starch on the metabolism of lipids and carbohydrates in male Wistar rats. 20 male rats were divided into two groups, which received a diet with 9.5% (DAP) and 18.1% (DAR) of resistant starch for 22 days. Weight, feed, and water consumption were analyzed and the concentrations of cholesterol and triglycerides in serum and muscle and hepatic and muscle glycogen were quantified. The data were analyzed by Tukey's test (p>0.05) and box-plot graphs. There were no significant differences in feed and water intake, but the animals in the DAP group showed an increase in weight (51.12g to 55.27g) while those in the DAR group decreased (49.01g to 44.15g). The DAR group showed a decrease in triglycerides, total serum cholesterol (from 125.761 mg/dL to 104.874 mg/dL), and muscle glycogen, but an increase in triglycerides in the gastrocnemius muscle compared to the DAP group (from 0.160 mg/dL to 0.259 mg/dL). These results point to a decrease in the glucose absorption speed in the group of animals with a diet with a higher amount of resistant starch, which may have induced a decrease in the processes of synthesis of triglycerides and cholesterol leading to an increase in catabolism of these substrates by the body, plastic adaptation of muscles for the use of fatty acids in their oxidative metabolism. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/16448 10.33448/rsd-v10i7.16448 |
url |
https://rsdjournal.org/index.php/rsd/article/view/16448 |
identifier_str_mv |
10.33448/rsd-v10i7.16448 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/16448/14677 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 7; e18110716448 Research, Society and Development; Vol. 10 Núm. 7; e18110716448 Research, Society and Development; v. 10 n. 7; e18110716448 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052679800750080 |