Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial

Detalhes bibliográficos
Autor(a) principal: Grunevald, Matheus
Data de Publicação: 2021
Outros Autores: Cantarelli, Romulo, Oballe, Harry Juan Rivera, Negrini, Thais De Cássia [UNESP], Arthur, Rodrigo Alex, da Silva, Eduardo Liberato, Herpich, Tiago Luís, Muniz, Francisco Wilker Mustafa Gomes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.20396/BJOS.V20I00.8663867
http://hdl.handle.net/11449/221756
Resumo: This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p<0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p<0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). Conclusion: Mouthrinse containing EO without alcohol presented a better taste perception when compared to the EO with alcohol, but no difference was observed in the antimicrobial potential of both EO solutions after a single rinse protocol.
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spelling Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical TrialAlcoholsBacteriaMouthwashesOils volatileTaste perceptionThis study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p<0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p<0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). Conclusion: Mouthrinse containing EO without alcohol presented a better taste perception when compared to the EO with alcohol, but no difference was observed in the antimicrobial potential of both EO solutions after a single rinse protocol.Federal University Rio Grande do SulPost-Graduate Program in Dentistry Federal University Rio Grande do SulPost-Graduate Program in Bioscience and Biotechnology applied to Pharmacy Department of Clinical Analysis São Paulo State UniversityProfessor of Oral Microbiology and Biochemistry and Cariology Department of Preventive and Community Dentistry Federal University of Rio Grande do SulPost- Graduate Program in Dentistry Federal University Rio Grande do SulProfessor of Periodontology Department of Semiology and Clinic Federal University of PelotasPost-Graduate Program in Bioscience and Biotechnology applied to Pharmacy Department of Clinical Analysis São Paulo State UniversityFederal University Rio Grande do SulUniversidade Estadual Paulista (UNESP)Federal University of Rio Grande do SulFederal University of PelotasGrunevald, MatheusCantarelli, RomuloOballe, Harry Juan RiveraNegrini, Thais De Cássia [UNESP]Arthur, Rodrigo Alexda Silva, Eduardo LiberatoHerpich, Tiago LuísMuniz, Francisco Wilker Mustafa Gomes2022-04-28T19:40:16Z2022-04-28T19:40:16Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-9http://dx.doi.org/10.20396/BJOS.V20I00.8663867Brazilian Journal of Oral Sciences, v. 20, p. 1-9.1677-32251677-3217http://hdl.handle.net/11449/22175610.20396/BJOS.V20I00.86638672-s2.0-85106592173Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Oral Sciencesinfo:eu-repo/semantics/openAccess2022-04-28T19:40:16Zoai:repositorio.unesp.br:11449/221756Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:40:16Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
title Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
spellingShingle Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
Grunevald, Matheus
Alcohols
Bacteria
Mouthwashes
Oils volatile
Taste perception
title_short Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
title_full Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
title_fullStr Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
title_full_unstemmed Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
title_sort Antimicrobial Potential of Essential Oils Mouthrinses With and Without Alcohol: A Randomized Clinical Trial
author Grunevald, Matheus
author_facet Grunevald, Matheus
Cantarelli, Romulo
Oballe, Harry Juan Rivera
Negrini, Thais De Cássia [UNESP]
Arthur, Rodrigo Alex
da Silva, Eduardo Liberato
Herpich, Tiago Luís
Muniz, Francisco Wilker Mustafa Gomes
author_role author
author2 Cantarelli, Romulo
Oballe, Harry Juan Rivera
Negrini, Thais De Cássia [UNESP]
Arthur, Rodrigo Alex
da Silva, Eduardo Liberato
Herpich, Tiago Luís
Muniz, Francisco Wilker Mustafa Gomes
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Federal University Rio Grande do Sul
Universidade Estadual Paulista (UNESP)
Federal University of Rio Grande do Sul
Federal University of Pelotas
dc.contributor.author.fl_str_mv Grunevald, Matheus
Cantarelli, Romulo
Oballe, Harry Juan Rivera
Negrini, Thais De Cássia [UNESP]
Arthur, Rodrigo Alex
da Silva, Eduardo Liberato
Herpich, Tiago Luís
Muniz, Francisco Wilker Mustafa Gomes
dc.subject.por.fl_str_mv Alcohols
Bacteria
Mouthwashes
Oils volatile
Taste perception
topic Alcohols
Bacteria
Mouthwashes
Oils volatile
Taste perception
description This study aimed to compare the microbiological potential and gustatory perception of essential oils (EO) mouthrinses containing and not containing alcohol. Methods: Twenty healthy adult volunteers rinsed with 10mL of the following test solutions: EO with alcohol, EO without alcohol, or a control solution (saline solution with mint essence). A washout period of at least seven days was adopted after a single-use protocol of the respective solution. All participants used all three tested substances. Antimicrobial potential was assessed by counting salivary total viable bacteria both before and after each rinse. Gustatory perception was evaluated using the Visual Analogue Scale (VAS). Multiple comparisons were performed with the Wilcoxon test, using Bonferroni correction. Results: Both EO solutions presented a higher antimicrobial potential in comparison to the control solution (p<0.017). However, no significant difference in antimicrobial potential was observed between EO containing or not containing alcohol (p=0.218). VAS of EO with alcohol (median: 2.7) was similar to control solution (median: 1.6) (p=0.287). A better gustatory perception was observed of the EO without alcohol (median 7.6) when compared to the control solution (p<0.0001). When EO groups were compared, EO without alcohol also demonstrated a significantly better gustatory perception (p=0.001). Conclusion: Mouthrinse containing EO without alcohol presented a better taste perception when compared to the EO with alcohol, but no difference was observed in the antimicrobial potential of both EO solutions after a single rinse protocol.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
2022-04-28T19:40:16Z
2022-04-28T19:40:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.20396/BJOS.V20I00.8663867
Brazilian Journal of Oral Sciences, v. 20, p. 1-9.
1677-3225
1677-3217
http://hdl.handle.net/11449/221756
10.20396/BJOS.V20I00.8663867
2-s2.0-85106592173
url http://dx.doi.org/10.20396/BJOS.V20I00.8663867
http://hdl.handle.net/11449/221756
identifier_str_mv Brazilian Journal of Oral Sciences, v. 20, p. 1-9.
1677-3225
1677-3217
10.20396/BJOS.V20I00.8663867
2-s2.0-85106592173
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Oral Sciences
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-9
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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