Galleria mellonella as an experimental model for studying periodontopathogens

Detalhes bibliográficos
Autor(a) principal: Santos, Thaís Aguiar [UNESP]
Data de Publicação: 2020
Outros Autores: Scorzoni, Liliana [UNESP], Santos, Aline de Castro [UNESP], Junqueira, Juliana Campos [UNESP], Anbinder, Ana Lia [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4103/jisp.jisp_631_19
http://hdl.handle.net/11449/208195
Resumo: In the present study, Galleria mellonella was evaluated as a potential infection model for periodontal bacteria, more specifically, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans. All the bacteria evaluated were pathogenic to G. mellonella, causing their death in a concentration-dependent manner, and a decrease in their hemocyte count. Moreover, it was possible to recover the bacteria from the larvae hemolymph and determine the colony-forming units per larvae. G. mellonella is an effective model that may help to better understand the host-microbe interactions in periodontics.
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spelling Galleria mellonella as an experimental model for studying periodontopathogensAggregatibacter actinomycetemcomitansFusobacterium nucleatumGalleria mellonellaPeriodontal diseasesPorphyromonas gingivalisIn the present study, Galleria mellonella was evaluated as a potential infection model for periodontal bacteria, more specifically, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans. All the bacteria evaluated were pathogenic to G. mellonella, causing their death in a concentration-dependent manner, and a decrease in their hemocyte count. Moreover, it was possible to recover the bacteria from the larvae hemolymph and determine the colony-forming units per larvae. G. mellonella is an effective model that may help to better understand the host-microbe interactions in periodontics.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Bioscience and Oral Diagnosis Institute of Science and Technology São Paulo State University (Unesp)Department of Bioscience and Oral Diagnosis Institute of Science and Technology São Paulo State University (Unesp)FAPESP: 2016/06946-1FAPESP: 2017/05439-1Universidade Estadual Paulista (Unesp)Santos, Thaís Aguiar [UNESP]Scorzoni, Liliana [UNESP]Santos, Aline de Castro [UNESP]Junqueira, Juliana Campos [UNESP]Anbinder, Ana Lia [UNESP]2021-06-25T11:07:59Z2021-06-25T11:07:59Z2020-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article593-596http://dx.doi.org/10.4103/jisp.jisp_631_19Journal of Indian Society of Periodontology, v. 24, n. 6, p. 593-596, 2020.0975-15800972-124Xhttp://hdl.handle.net/11449/20819510.4103/jisp.jisp_631_192-s2.0-85096801487Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Indian Society of Periodontologyinfo:eu-repo/semantics/openAccess2021-10-23T18:56:48Zoai:repositorio.unesp.br:11449/208195Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:12:24.583223Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Galleria mellonella as an experimental model for studying periodontopathogens
title Galleria mellonella as an experimental model for studying periodontopathogens
spellingShingle Galleria mellonella as an experimental model for studying periodontopathogens
Santos, Thaís Aguiar [UNESP]
Aggregatibacter actinomycetemcomitans
Fusobacterium nucleatum
Galleria mellonella
Periodontal diseases
Porphyromonas gingivalis
title_short Galleria mellonella as an experimental model for studying periodontopathogens
title_full Galleria mellonella as an experimental model for studying periodontopathogens
title_fullStr Galleria mellonella as an experimental model for studying periodontopathogens
title_full_unstemmed Galleria mellonella as an experimental model for studying periodontopathogens
title_sort Galleria mellonella as an experimental model for studying periodontopathogens
author Santos, Thaís Aguiar [UNESP]
author_facet Santos, Thaís Aguiar [UNESP]
Scorzoni, Liliana [UNESP]
Santos, Aline de Castro [UNESP]
Junqueira, Juliana Campos [UNESP]
Anbinder, Ana Lia [UNESP]
author_role author
author2 Scorzoni, Liliana [UNESP]
Santos, Aline de Castro [UNESP]
Junqueira, Juliana Campos [UNESP]
Anbinder, Ana Lia [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Santos, Thaís Aguiar [UNESP]
Scorzoni, Liliana [UNESP]
Santos, Aline de Castro [UNESP]
Junqueira, Juliana Campos [UNESP]
Anbinder, Ana Lia [UNESP]
dc.subject.por.fl_str_mv Aggregatibacter actinomycetemcomitans
Fusobacterium nucleatum
Galleria mellonella
Periodontal diseases
Porphyromonas gingivalis
topic Aggregatibacter actinomycetemcomitans
Fusobacterium nucleatum
Galleria mellonella
Periodontal diseases
Porphyromonas gingivalis
description In the present study, Galleria mellonella was evaluated as a potential infection model for periodontal bacteria, more specifically, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans. All the bacteria evaluated were pathogenic to G. mellonella, causing their death in a concentration-dependent manner, and a decrease in their hemocyte count. Moreover, it was possible to recover the bacteria from the larvae hemolymph and determine the colony-forming units per larvae. G. mellonella is an effective model that may help to better understand the host-microbe interactions in periodontics.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-01
2021-06-25T11:07:59Z
2021-06-25T11:07:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4103/jisp.jisp_631_19
Journal of Indian Society of Periodontology, v. 24, n. 6, p. 593-596, 2020.
0975-1580
0972-124X
http://hdl.handle.net/11449/208195
10.4103/jisp.jisp_631_19
2-s2.0-85096801487
url http://dx.doi.org/10.4103/jisp.jisp_631_19
http://hdl.handle.net/11449/208195
identifier_str_mv Journal of Indian Society of Periodontology, v. 24, n. 6, p. 593-596, 2020.
0975-1580
0972-124X
10.4103/jisp.jisp_631_19
2-s2.0-85096801487
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Indian Society of Periodontology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 593-596
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128618516185088

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