Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review

Detalhes bibliográficos
Autor(a) principal: Santinoni, Carolina dos Santos [UNESP]
Data de Publicação: 2017
Outros Autores: Oliveira, Hiskell Francine Fernandes [UNESP], Batista, Victor Eduardo de Souza [UNESP], Lemos, Cleidiel Aparecido Araujo [UNESP], Verri, Fellippo Ramos [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.jphotobiol.2017.03.004
http://hdl.handle.net/11449/169535
Resumo: Purpose This systematic review evaluates the effectiveness of low-level laser therapy (LLLT) to enhance maxillofacial area bone repair. Methods A comprehensive search of studies published up to February 2017 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results The 15 selected studies evaluated a total of 374 patients (mean age, 28.5 years) who were treated with LLLT. Gallium-arsenide (GaAs) and gallium aluminium arsenide (GaAlAs) were the most commonly used devices, and LLLT parameters varied greatly. Wavelengths varied from 500 to 1000 nm. Tooth extraction, distraction osteogenesis, maxillary expansion, periodontal defects, orthodontic movement and maxillary cystic defects were evaluated. From the 15 selected studies, six evaluated bone repair (primary outcomes). Of these, four studies showed improvement in bone formation after using LLLT, two demonstrated improved results for only one follow up period, and one showed no additional benefits. The other 9 studies evaluated secondary parameters related to healing (secondary outcomes) in the maxillofacial area after applying LLLT, including anti-inflammatory, analgesic, and healing accelerator effects, and quality of life related to oral health. There were no adverse or negative effects of LLLT reported. Conclusion Within the limitation of this review, a possible improvement in bone density can be found when LLLT is applied postoperatively in maxillofacial bony defects. LLLT also seems to promote anti-inflammatory and analgesic effects and accelerate healing, as well as enhance quality of life related to oral health. However, LLLT use protocols need to be standardized before more specific conclusions can be drawn about this subject.
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spelling Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic reviewBoneBone regenerationDentistryLasersLow-level laser therapyMaxillofacialReviewSystematic reviewPurpose This systematic review evaluates the effectiveness of low-level laser therapy (LLLT) to enhance maxillofacial area bone repair. Methods A comprehensive search of studies published up to February 2017 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results The 15 selected studies evaluated a total of 374 patients (mean age, 28.5 years) who were treated with LLLT. Gallium-arsenide (GaAs) and gallium aluminium arsenide (GaAlAs) were the most commonly used devices, and LLLT parameters varied greatly. Wavelengths varied from 500 to 1000 nm. Tooth extraction, distraction osteogenesis, maxillary expansion, periodontal defects, orthodontic movement and maxillary cystic defects were evaluated. From the 15 selected studies, six evaluated bone repair (primary outcomes). Of these, four studies showed improvement in bone formation after using LLLT, two demonstrated improved results for only one follow up period, and one showed no additional benefits. The other 9 studies evaluated secondary parameters related to healing (secondary outcomes) in the maxillofacial area after applying LLLT, including anti-inflammatory, analgesic, and healing accelerator effects, and quality of life related to oral health. There were no adverse or negative effects of LLLT reported. Conclusion Within the limitation of this review, a possible improvement in bone density can be found when LLLT is applied postoperatively in maxillofacial bony defects. LLLT also seems to promote anti-inflammatory and analgesic effects and accelerate healing, as well as enhance quality of life related to oral health. However, LLLT use protocols need to be standardized before more specific conclusions can be drawn about this subject.Dental School Univ. Estadual Paulista – UNESPDental School Univ. do Oeste Paulista – UNOESTEDental School Univ. Estadual Paulista – UNESPUniversidade Estadual Paulista (Unesp)Univ. do Oeste Paulista – UNOESTESantinoni, Carolina dos Santos [UNESP]Oliveira, Hiskell Francine Fernandes [UNESP]Batista, Victor Eduardo de Souza [UNESP]Lemos, Cleidiel Aparecido Araujo [UNESP]Verri, Fellippo Ramos [UNESP]2018-12-11T16:46:21Z2018-12-11T16:46:21Z2017-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article83-89application/pdfhttp://dx.doi.org/10.1016/j.jphotobiol.2017.03.004Journal of Photochemistry and Photobiology B: Biology, v. 169, p. 83-89.1873-26821011-1344http://hdl.handle.net/11449/16953510.1016/j.jphotobiol.2017.03.0042-s2.0-850150629852-s2.0-85015062985.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Photochemistry and Photobiology B: Biology0,698info:eu-repo/semantics/openAccess2023-10-26T06:10:29Zoai:repositorio.unesp.br:11449/169535Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:02:57.966317Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
title Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
spellingShingle Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
Santinoni, Carolina dos Santos [UNESP]
Bone
Bone regeneration
Dentistry
Lasers
Low-level laser therapy
Maxillofacial
Review
Systematic review
title_short Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
title_full Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
title_fullStr Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
title_full_unstemmed Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
title_sort Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review
author Santinoni, Carolina dos Santos [UNESP]
author_facet Santinoni, Carolina dos Santos [UNESP]
Oliveira, Hiskell Francine Fernandes [UNESP]
Batista, Victor Eduardo de Souza [UNESP]
Lemos, Cleidiel Aparecido Araujo [UNESP]
Verri, Fellippo Ramos [UNESP]
author_role author
author2 Oliveira, Hiskell Francine Fernandes [UNESP]
Batista, Victor Eduardo de Souza [UNESP]
Lemos, Cleidiel Aparecido Araujo [UNESP]
Verri, Fellippo Ramos [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Univ. do Oeste Paulista – UNOESTE
dc.contributor.author.fl_str_mv Santinoni, Carolina dos Santos [UNESP]
Oliveira, Hiskell Francine Fernandes [UNESP]
Batista, Victor Eduardo de Souza [UNESP]
Lemos, Cleidiel Aparecido Araujo [UNESP]
Verri, Fellippo Ramos [UNESP]
dc.subject.por.fl_str_mv Bone
Bone regeneration
Dentistry
Lasers
Low-level laser therapy
Maxillofacial
Review
Systematic review
topic Bone
Bone regeneration
Dentistry
Lasers
Low-level laser therapy
Maxillofacial
Review
Systematic review
description Purpose This systematic review evaluates the effectiveness of low-level laser therapy (LLLT) to enhance maxillofacial area bone repair. Methods A comprehensive search of studies published up to February 2017 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results The 15 selected studies evaluated a total of 374 patients (mean age, 28.5 years) who were treated with LLLT. Gallium-arsenide (GaAs) and gallium aluminium arsenide (GaAlAs) were the most commonly used devices, and LLLT parameters varied greatly. Wavelengths varied from 500 to 1000 nm. Tooth extraction, distraction osteogenesis, maxillary expansion, periodontal defects, orthodontic movement and maxillary cystic defects were evaluated. From the 15 selected studies, six evaluated bone repair (primary outcomes). Of these, four studies showed improvement in bone formation after using LLLT, two demonstrated improved results for only one follow up period, and one showed no additional benefits. The other 9 studies evaluated secondary parameters related to healing (secondary outcomes) in the maxillofacial area after applying LLLT, including anti-inflammatory, analgesic, and healing accelerator effects, and quality of life related to oral health. There were no adverse or negative effects of LLLT reported. Conclusion Within the limitation of this review, a possible improvement in bone density can be found when LLLT is applied postoperatively in maxillofacial bony defects. LLLT also seems to promote anti-inflammatory and analgesic effects and accelerate healing, as well as enhance quality of life related to oral health. However, LLLT use protocols need to be standardized before more specific conclusions can be drawn about this subject.
publishDate 2017
dc.date.none.fl_str_mv 2017-04-01
2018-12-11T16:46:21Z
2018-12-11T16:46:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.jphotobiol.2017.03.004
Journal of Photochemistry and Photobiology B: Biology, v. 169, p. 83-89.
1873-2682
1011-1344
http://hdl.handle.net/11449/169535
10.1016/j.jphotobiol.2017.03.004
2-s2.0-85015062985
2-s2.0-85015062985.pdf
url http://dx.doi.org/10.1016/j.jphotobiol.2017.03.004
http://hdl.handle.net/11449/169535
identifier_str_mv Journal of Photochemistry and Photobiology B: Biology, v. 169, p. 83-89.
1873-2682
1011-1344
10.1016/j.jphotobiol.2017.03.004
2-s2.0-85015062985
2-s2.0-85015062985.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Photochemistry and Photobiology B: Biology
0,698
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 83-89
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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