Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter

Detalhes bibliográficos
Autor(a) principal: Orsi, Kelly Cristina Sbampato Calado
Data de Publicação: 2021
Outros Autores: Kita, Vanessa Yukie, de Souza, Adja Havreluk Paiva, Tsunemi, Miriam Harumi, Avelar, Ariane Ferreira Machado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1097/JPN.0000000000000571
http://hdl.handle.net/11449/231572
Resumo: The objective of this study was to verify the influence of the gravitational infusion method or syringe infusion pump on changes in hemolysis markers of irradiated and nonirradiated packed red blood cells (PRBCs) in vitro administered in a neonate peripheral intravenous catheter. An experimental study was conducted in a laboratory under controlled environmental conditions. Irradiated and nonirradiated PRBCs were administered in triplicate by the gravitational method and 10-mL/hour syringe infusion pump, in peripheral intravenous catheter, Vialon, 24-G caliber. Aliquots were collected directly from the PRBC bag, after manual filling of the infusion system and after infusion by the catheters. The following hemolytic markers were analyzed: degree of hemolysis (%), hematocrit (Ht, %), free hemoglobin (fHb, g/dL), potassium (K, mmol/L), and lactate dehydrogenase (LDH, U/L). Mann-Whitney and Student's t tests were used, P ≤ .05. The gravitational method significantly influenced increasing fHb (P = .007), Ht (P = .002), K (P = .002), and LDH (P = .003) values after PRBC irradiated infusion. The infusion of irradiated and non-irradiated PRBCs interferes with changes in hemolytic markers with the gravitational method. Syringe infusion pump proved to be a beneficial and safe alternative to irradiated and nonirradiated PRBC transfusion in newborns.
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spelling Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral CatheterThe objective of this study was to verify the influence of the gravitational infusion method or syringe infusion pump on changes in hemolysis markers of irradiated and nonirradiated packed red blood cells (PRBCs) in vitro administered in a neonate peripheral intravenous catheter. An experimental study was conducted in a laboratory under controlled environmental conditions. Irradiated and nonirradiated PRBCs were administered in triplicate by the gravitational method and 10-mL/hour syringe infusion pump, in peripheral intravenous catheter, Vialon, 24-G caliber. Aliquots were collected directly from the PRBC bag, after manual filling of the infusion system and after infusion by the catheters. The following hemolytic markers were analyzed: degree of hemolysis (%), hematocrit (Ht, %), free hemoglobin (fHb, g/dL), potassium (K, mmol/L), and lactate dehydrogenase (LDH, U/L). Mann-Whitney and Student's t tests were used, P ≤ .05. The gravitational method significantly influenced increasing fHb (P = .007), Ht (P = .002), K (P = .002), and LDH (P = .003) values after PRBC irradiated infusion. The infusion of irradiated and non-irradiated PRBCs interferes with changes in hemolytic markers with the gravitational method. Syringe infusion pump proved to be a beneficial and safe alternative to irradiated and nonirradiated PRBC transfusion in newborns.Nursing School, Federal University of São Paulo, São Paulo, Brazil (Drs Orsi and Avelar and Mss Kita and de Souza); and Department of Biostatistics, Paulista State University Julio de Mesquita Filho, Botucatu, São Paulo, Brazil (Dr Tsunemi)Universidade Estadual Paulista (UNESP)Orsi, Kelly Cristina Sbampato CaladoKita, Vanessa Yukiede Souza, Adja Havreluk PaivaTsunemi, Miriam HarumiAvelar, Ariane Ferreira Machado2022-04-29T08:46:12Z2022-04-29T08:46:12Z2021-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleE40-E49http://dx.doi.org/10.1097/JPN.0000000000000571The Journal of perinatal & neonatal nursing, v. 35, n. 4, p. E40-E49, 2021.1550-5073http://hdl.handle.net/11449/23157210.1097/JPN.00000000000005712-s2.0-85121476730Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengThe Journal of perinatal & neonatal nursinginfo:eu-repo/semantics/openAccess2024-08-15T18:46:41Zoai:repositorio.unesp.br:11449/231572Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-15T18:46:41Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
title Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
spellingShingle Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
Orsi, Kelly Cristina Sbampato Calado
title_short Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
title_full Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
title_fullStr Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
title_full_unstemmed Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
title_sort Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter
author Orsi, Kelly Cristina Sbampato Calado
author_facet Orsi, Kelly Cristina Sbampato Calado
Kita, Vanessa Yukie
de Souza, Adja Havreluk Paiva
Tsunemi, Miriam Harumi
Avelar, Ariane Ferreira Machado
author_role author
author2 Kita, Vanessa Yukie
de Souza, Adja Havreluk Paiva
Tsunemi, Miriam Harumi
Avelar, Ariane Ferreira Machado
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Orsi, Kelly Cristina Sbampato Calado
Kita, Vanessa Yukie
de Souza, Adja Havreluk Paiva
Tsunemi, Miriam Harumi
Avelar, Ariane Ferreira Machado
description The objective of this study was to verify the influence of the gravitational infusion method or syringe infusion pump on changes in hemolysis markers of irradiated and nonirradiated packed red blood cells (PRBCs) in vitro administered in a neonate peripheral intravenous catheter. An experimental study was conducted in a laboratory under controlled environmental conditions. Irradiated and nonirradiated PRBCs were administered in triplicate by the gravitational method and 10-mL/hour syringe infusion pump, in peripheral intravenous catheter, Vialon, 24-G caliber. Aliquots were collected directly from the PRBC bag, after manual filling of the infusion system and after infusion by the catheters. The following hemolytic markers were analyzed: degree of hemolysis (%), hematocrit (Ht, %), free hemoglobin (fHb, g/dL), potassium (K, mmol/L), and lactate dehydrogenase (LDH, U/L). Mann-Whitney and Student's t tests were used, P ≤ .05. The gravitational method significantly influenced increasing fHb (P = .007), Ht (P = .002), K (P = .002), and LDH (P = .003) values after PRBC irradiated infusion. The infusion of irradiated and non-irradiated PRBCs interferes with changes in hemolytic markers with the gravitational method. Syringe infusion pump proved to be a beneficial and safe alternative to irradiated and nonirradiated PRBC transfusion in newborns.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-01
2022-04-29T08:46:12Z
2022-04-29T08:46:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1097/JPN.0000000000000571
The Journal of perinatal & neonatal nursing, v. 35, n. 4, p. E40-E49, 2021.
1550-5073
http://hdl.handle.net/11449/231572
10.1097/JPN.0000000000000571
2-s2.0-85121476730
url http://dx.doi.org/10.1097/JPN.0000000000000571
http://hdl.handle.net/11449/231572
identifier_str_mv The Journal of perinatal & neonatal nursing, v. 35, n. 4, p. E40-E49, 2021.
1550-5073
10.1097/JPN.0000000000000571
2-s2.0-85121476730
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv The Journal of perinatal & neonatal nursing
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv E40-E49
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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