Sedative and clinical effects of the pharmacopuncture with xylazine in dogs
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0102-86502014000100007 http://hdl.handle.net/11449/112336 |
Resumo: | PURPOSE: To investigate the sedative and clinical effects of the pharmacopuncture with xylazine, compared to the conventional dose of a intramuscular injection in dogs.METHODS: Twelve dogs were randomly distributed in two groups of six animals and treated as follows: control group (X-IM): 1mg kg(-1) of xylazine given intramuscularly (IM); pharmacopuncture group (X-Yintang): 0.1mg kg(-1) of xylazine diluted to 0.5 mL of saline injected into the Yin Tang acupoint. Heart rate, cardiac rhythm (ECG), systolic arterial blood pressure (SABP), respiratory rate (RR), rectal temperature (RT), blood glucose concentration, degree of sedation and adverse effects were evaluated.RESULTS: Sedative effect was observed in both groups. The degree of sedation was greater in X-IM only at 15 min when compared with X-Yintang group. Cardiovascular established was observed in X-Yintang group, while marked reduction in the HR and increased incidence of ECG abnormalities were detected in X-IM. In both treatment groups, minimal changes were observed in relation to SABP, RR, RT and blood glucose. High incidence (66%) of vomiting was observed in X-IM, while this adverse effect was absent in X-Yintang.CONCLUSION: Pharmacopuncture with xylazine induced clinically relevant sedative effects in dogs, with the advantage of reduction of undesirable side effects associated with alpha(2)-agonists, including bradycardia, cardiac arrhythmias, and emesis. |
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Sedative and clinical effects of the pharmacopuncture with xylazine in dogsAcupunctureSedationAnxiolytic AgentsXylazineDogsPURPOSE: To investigate the sedative and clinical effects of the pharmacopuncture with xylazine, compared to the conventional dose of a intramuscular injection in dogs.METHODS: Twelve dogs were randomly distributed in two groups of six animals and treated as follows: control group (X-IM): 1mg kg(-1) of xylazine given intramuscularly (IM); pharmacopuncture group (X-Yintang): 0.1mg kg(-1) of xylazine diluted to 0.5 mL of saline injected into the Yin Tang acupoint. Heart rate, cardiac rhythm (ECG), systolic arterial blood pressure (SABP), respiratory rate (RR), rectal temperature (RT), blood glucose concentration, degree of sedation and adverse effects were evaluated.RESULTS: Sedative effect was observed in both groups. The degree of sedation was greater in X-IM only at 15 min when compared with X-Yintang group. Cardiovascular established was observed in X-Yintang group, while marked reduction in the HR and increased incidence of ECG abnormalities were detected in X-IM. In both treatment groups, minimal changes were observed in relation to SABP, RR, RT and blood glucose. High incidence (66%) of vomiting was observed in X-IM, while this adverse effect was absent in X-Yintang.CONCLUSION: Pharmacopuncture with xylazine induced clinically relevant sedative effects in dogs, with the advantage of reduction of undesirable side effects associated with alpha(2)-agonists, including bradycardia, cardiac arrhythmias, and emesis.Oeste Paulista Univ UNOESTE, Scholl Vet Med, Dept Vet Surg & Anestesiol, Presidente Prudente, SP, BrazilSao Paulo State Univ UNESP, Scholl Vet Med, Dept Clin Vet, Botucatu, SP, BrazilAndradina Educ Fdn FEA, Scholl Vet Med, Dept Vet Anestesiol, Andradina, SP, BrazilUniv Oeste Paulista, Scholl Vet Med, Dept Vet Surg & Anestesiol, Presidente Prudente, SP, BrazilSao Paulo State Univ UNESP, Scholl Vet Med, Dept Clin Vet, Botucatu, SP, BrazilActa Cirúrgica BrasileiraUniversidade do Oeste Paulista (UNOESTE)Universidade Estadual Paulista (Unesp)Andradina Educ Fdn FEACassu, Renata NavarroMelchert, Alessandra [UNESP]Bignelli Canoa, Jiancarlo TortozaOliveira Martins, Paula Denise de2014-12-03T13:10:38Z2014-12-03T13:10:38Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article47-52application/pdfhttp://dx.doi.org/10.1590/S0102-86502014000100007Acta Cirurgica Brasileira. São Paulo: Acta Cirurgica Brasileira, v. 29, n. 1, p. 47-52, 2014.0102-8650http://hdl.handle.net/11449/112336S0102-86502014000100007WOS:000330868700007S0102-86502014000100007.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Cirúrgica Brasileira0.9330,395info:eu-repo/semantics/openAccess2024-01-05T06:25:10Zoai:repositorio.unesp.br:11449/112336Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:11:07.615117Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
title |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
spellingShingle |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs Cassu, Renata Navarro Acupuncture Sedation Anxiolytic Agents Xylazine Dogs |
title_short |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
title_full |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
title_fullStr |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
title_full_unstemmed |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
title_sort |
Sedative and clinical effects of the pharmacopuncture with xylazine in dogs |
author |
Cassu, Renata Navarro |
author_facet |
Cassu, Renata Navarro Melchert, Alessandra [UNESP] Bignelli Canoa, Jiancarlo Tortoza Oliveira Martins, Paula Denise de |
author_role |
author |
author2 |
Melchert, Alessandra [UNESP] Bignelli Canoa, Jiancarlo Tortoza Oliveira Martins, Paula Denise de |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade do Oeste Paulista (UNOESTE) Universidade Estadual Paulista (Unesp) Andradina Educ Fdn FEA |
dc.contributor.author.fl_str_mv |
Cassu, Renata Navarro Melchert, Alessandra [UNESP] Bignelli Canoa, Jiancarlo Tortoza Oliveira Martins, Paula Denise de |
dc.subject.por.fl_str_mv |
Acupuncture Sedation Anxiolytic Agents Xylazine Dogs |
topic |
Acupuncture Sedation Anxiolytic Agents Xylazine Dogs |
description |
PURPOSE: To investigate the sedative and clinical effects of the pharmacopuncture with xylazine, compared to the conventional dose of a intramuscular injection in dogs.METHODS: Twelve dogs were randomly distributed in two groups of six animals and treated as follows: control group (X-IM): 1mg kg(-1) of xylazine given intramuscularly (IM); pharmacopuncture group (X-Yintang): 0.1mg kg(-1) of xylazine diluted to 0.5 mL of saline injected into the Yin Tang acupoint. Heart rate, cardiac rhythm (ECG), systolic arterial blood pressure (SABP), respiratory rate (RR), rectal temperature (RT), blood glucose concentration, degree of sedation and adverse effects were evaluated.RESULTS: Sedative effect was observed in both groups. The degree of sedation was greater in X-IM only at 15 min when compared with X-Yintang group. Cardiovascular established was observed in X-Yintang group, while marked reduction in the HR and increased incidence of ECG abnormalities were detected in X-IM. In both treatment groups, minimal changes were observed in relation to SABP, RR, RT and blood glucose. High incidence (66%) of vomiting was observed in X-IM, while this adverse effect was absent in X-Yintang.CONCLUSION: Pharmacopuncture with xylazine induced clinically relevant sedative effects in dogs, with the advantage of reduction of undesirable side effects associated with alpha(2)-agonists, including bradycardia, cardiac arrhythmias, and emesis. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-12-03T13:10:38Z 2014-12-03T13:10:38Z 2014-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0102-86502014000100007 Acta Cirurgica Brasileira. São Paulo: Acta Cirurgica Brasileira, v. 29, n. 1, p. 47-52, 2014. 0102-8650 http://hdl.handle.net/11449/112336 S0102-86502014000100007 WOS:000330868700007 S0102-86502014000100007.pdf |
url |
http://dx.doi.org/10.1590/S0102-86502014000100007 http://hdl.handle.net/11449/112336 |
identifier_str_mv |
Acta Cirurgica Brasileira. São Paulo: Acta Cirurgica Brasileira, v. 29, n. 1, p. 47-52, 2014. 0102-8650 S0102-86502014000100007 WOS:000330868700007 S0102-86502014000100007.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Acta Cirúrgica Brasileira 0.933 0,395 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
47-52 application/pdf |
dc.publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129401582256128 |