Immunogenicity evaluation of proteins from a Mycobacterium bovis isolated from cattle in the State of Goiás, Brasil

• Autor(a) principal: Fortes, Cinthya Marques
• Data de Publicação: 2012
• Outros Autores: Marques, Bruno Souza, Rocha, Viviane Cambuí Mesquita, Junqueira-Kipnis, Ana Paula
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/51728
• topic: Tuberculose bovina; Diagnóstico; Proteínas; Bovine tuberculosis; Diagnostic; Proteins

Bovine tuberculosis, persists in several countries as a threat to health of the herds despite the efforts given to the control and eradication of the disease. In order to detect immunogenic proteins with a potential to be used in a bovine tuberculosis diagnosis test, serum samples obtained from reactors and no reactors to intradermal tuberculin test, were evaluated for reactivity to Mycobacterium bovis antigens from a bacilli originated in Goiás – Brazil. The proteins immunogenicity from M. bovis was obtained by Western blot according to the molecular weight profile. The majority of the PPD positive bovine (67.92%) recognized a protein with 26kDa, suggesting the use of this protein in a serological test for bovine tuberculosis.