MATHEMATICAL MODELING, AUTOMATION AND CONTROL OF THE BIOCONVERSION OF SORBITOL TO SORBOSE IN THE VITAMIN C PRODUCTION PROCESS I. MATHEMATICAL MODELING

• Autor(a) principal: Bonomi,A.
• Data de Publicação: 1997
• Outros Autores: Fleury,A.T., Augusto,E.F.P., Mattos,M.N., Magossi,L.R.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Chemical Engineering
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66321997000400001
• topic: Mathematical modeling; control; bioconversion

In 1990, the Biotechnology and the Control Systems Groups of IPT started developing a system for the control and automation of fermentation processes, applied to the oxidation of sorbitol to sorbose by the bacteria Gluconobacter oxydans, the microbial step of the vitamin C production process, that was chosen as a case study. Initially, a thirteen-parameter model was fitted to represent the batch operation of the system utilizing a nonlinear regression analysis, the flexible polyhedron method. Based on these results, a model for the continuous process (with the same kinetic equations) was constructed and its optimum operating point obtained