How are HCV-infected patients being identified in Brazil: a multicenter study
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Infectious Diseases |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100034 |
Resumo: | ABSTRACT Background: Hepatitis C is an important health problem. In Brazil, 1-2 million people are infected. Despite this expressive number, and the availability of very successful treatment, many patients remained undiagnosed mainly because of the asymptomatic nature of the infection. Objectives: To describe epidemiological characteristics of HCV-infected patients seen at referral centers in Brazil, the source of referral, and the time spanned to reach a reference center, in order to improve the identification of undiagnosed patients. Methods: Multicenter observational, cross-sectional study carried out in 15 centers of Brazil, between January/2016 and June/2017. Data of patients with a confirmed diagnosis (anti-HCV and HCV-RNA) were collected by interview using standard questionnaires and by review of charts. Results: Two thousand patients were included; 55.1% were male, mean age 58 ± 11 years. Only 14.9% had higher education and 84.2% received up to five monthly minimum Brazilian wages (approximately US$260.00/month). The time between diagnosis and beginning of follow-up was 22.9 months. The most common reasons for testing were check-up (33.2%) and blood donation (19%). General practitioners diagnosed most of the patients (30.1%). Fibrosis stage was mainly evaluated by liver biopsy (61.5%) and 31.3% of the patients were cirrhotic at diagnosis. Conclusions: This multicenter Brazilian study showed that the mean time to reach a referral center for treatment was almost two years. Primary care physicians diagnoses most hepatitis C cases in the country. Population campaigns and medical education should be encouraged to intensify screening of asymptomatic individuals, considering the efficiency of check-ups in identifying new patients. |
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Brazilian Journal of Infectious Diseases |
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How are HCV-infected patients being identified in Brazil: a multicenter studyEpidemiologyhepatitis CHCVBrazilABSTRACT Background: Hepatitis C is an important health problem. In Brazil, 1-2 million people are infected. Despite this expressive number, and the availability of very successful treatment, many patients remained undiagnosed mainly because of the asymptomatic nature of the infection. Objectives: To describe epidemiological characteristics of HCV-infected patients seen at referral centers in Brazil, the source of referral, and the time spanned to reach a reference center, in order to improve the identification of undiagnosed patients. Methods: Multicenter observational, cross-sectional study carried out in 15 centers of Brazil, between January/2016 and June/2017. Data of patients with a confirmed diagnosis (anti-HCV and HCV-RNA) were collected by interview using standard questionnaires and by review of charts. Results: Two thousand patients were included; 55.1% were male, mean age 58 ± 11 years. Only 14.9% had higher education and 84.2% received up to five monthly minimum Brazilian wages (approximately US$260.00/month). The time between diagnosis and beginning of follow-up was 22.9 months. The most common reasons for testing were check-up (33.2%) and blood donation (19%). General practitioners diagnosed most of the patients (30.1%). Fibrosis stage was mainly evaluated by liver biopsy (61.5%) and 31.3% of the patients were cirrhotic at diagnosis. Conclusions: This multicenter Brazilian study showed that the mean time to reach a referral center for treatment was almost two years. Primary care physicians diagnoses most hepatitis C cases in the country. Population campaigns and medical education should be encouraged to intensify screening of asymptomatic individuals, considering the efficiency of check-ups in identifying new patients.Brazilian Society of Infectious Diseases2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100034Brazilian Journal of Infectious Diseases v.23 n.1 2019reponame:Brazilian Journal of Infectious Diseasesinstname:Brazilian Society of Infectious Diseases (BSID)instacron:BSID10.1016/j.bjid.2019.01.006info:eu-repo/semantics/openAccessPortari-Filho,Luiz H.Álvares-da-Silva,Mario R.Gonzalez,AlineFerreira,Adalgisa P.Nogueira,Cristiane V.Mendes-Correa,Maria C.Lima,José M.Lopes,Edmundo P.Brandão,Carlos E.Ivantes,CláudiaLyra,AndréLindenberg,AndreiaFerraz,Maria L.eng2019-05-16T00:00:00Zoai:scielo:S1413-86702019000100034Revistahttps://www.bjid.org.br/https://old.scielo.br/oai/scielo-oai.phpbjid@bjid.org.br||lgoldani@ufrgs.br1678-43911413-8670opendoar:2019-05-16T00:00Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID)false |
dc.title.none.fl_str_mv |
How are HCV-infected patients being identified in Brazil: a multicenter study |
title |
How are HCV-infected patients being identified in Brazil: a multicenter study |
spellingShingle |
How are HCV-infected patients being identified in Brazil: a multicenter study Portari-Filho,Luiz H. Epidemiology hepatitis C HCV Brazil |
title_short |
How are HCV-infected patients being identified in Brazil: a multicenter study |
title_full |
How are HCV-infected patients being identified in Brazil: a multicenter study |
title_fullStr |
How are HCV-infected patients being identified in Brazil: a multicenter study |
title_full_unstemmed |
How are HCV-infected patients being identified in Brazil: a multicenter study |
title_sort |
How are HCV-infected patients being identified in Brazil: a multicenter study |
author |
Portari-Filho,Luiz H. |
author_facet |
Portari-Filho,Luiz H. Álvares-da-Silva,Mario R. Gonzalez,Aline Ferreira,Adalgisa P. Nogueira,Cristiane V. Mendes-Correa,Maria C. Lima,José M. Lopes,Edmundo P. Brandão,Carlos E. Ivantes,Cláudia Lyra,André Lindenberg,Andreia Ferraz,Maria L. |
author_role |
author |
author2 |
Álvares-da-Silva,Mario R. Gonzalez,Aline Ferreira,Adalgisa P. Nogueira,Cristiane V. Mendes-Correa,Maria C. Lima,José M. Lopes,Edmundo P. Brandão,Carlos E. Ivantes,Cláudia Lyra,André Lindenberg,Andreia Ferraz,Maria L. |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Portari-Filho,Luiz H. Álvares-da-Silva,Mario R. Gonzalez,Aline Ferreira,Adalgisa P. Nogueira,Cristiane V. Mendes-Correa,Maria C. Lima,José M. Lopes,Edmundo P. Brandão,Carlos E. Ivantes,Cláudia Lyra,André Lindenberg,Andreia Ferraz,Maria L. |
dc.subject.por.fl_str_mv |
Epidemiology hepatitis C HCV Brazil |
topic |
Epidemiology hepatitis C HCV Brazil |
description |
ABSTRACT Background: Hepatitis C is an important health problem. In Brazil, 1-2 million people are infected. Despite this expressive number, and the availability of very successful treatment, many patients remained undiagnosed mainly because of the asymptomatic nature of the infection. Objectives: To describe epidemiological characteristics of HCV-infected patients seen at referral centers in Brazil, the source of referral, and the time spanned to reach a reference center, in order to improve the identification of undiagnosed patients. Methods: Multicenter observational, cross-sectional study carried out in 15 centers of Brazil, between January/2016 and June/2017. Data of patients with a confirmed diagnosis (anti-HCV and HCV-RNA) were collected by interview using standard questionnaires and by review of charts. Results: Two thousand patients were included; 55.1% were male, mean age 58 ± 11 years. Only 14.9% had higher education and 84.2% received up to five monthly minimum Brazilian wages (approximately US$260.00/month). The time between diagnosis and beginning of follow-up was 22.9 months. The most common reasons for testing were check-up (33.2%) and blood donation (19%). General practitioners diagnosed most of the patients (30.1%). Fibrosis stage was mainly evaluated by liver biopsy (61.5%) and 31.3% of the patients were cirrhotic at diagnosis. Conclusions: This multicenter Brazilian study showed that the mean time to reach a referral center for treatment was almost two years. Primary care physicians diagnoses most hepatitis C cases in the country. Population campaigns and medical education should be encouraged to intensify screening of asymptomatic individuals, considering the efficiency of check-ups in identifying new patients. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100034 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000100034 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjid.2019.01.006 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
Brazilian Journal of Infectious Diseases v.23 n.1 2019 reponame:Brazilian Journal of Infectious Diseases instname:Brazilian Society of Infectious Diseases (BSID) instacron:BSID |
instname_str |
Brazilian Society of Infectious Diseases (BSID) |
instacron_str |
BSID |
institution |
BSID |
reponame_str |
Brazilian Journal of Infectious Diseases |
collection |
Brazilian Journal of Infectious Diseases |
repository.name.fl_str_mv |
Brazilian Journal of Infectious Diseases - Brazilian Society of Infectious Diseases (BSID) |
repository.mail.fl_str_mv |
bjid@bjid.org.br||lgoldani@ufrgs.br |
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