Brazilian propolis: correlation between chemical composition and antimicrobial activity

Detalhes bibliográficos
Autor(a) principal: Salomão, Kelly
Data de Publicação: 2008
Outros Autores: Pereira, Paulo Roberto S., Campos, Leila C., Borba, Cintia M., Cabello, Pedro H., Marcucci, Maria Cristina, Castro, Solange L. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/28131
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Rio de Janeiro, RJ. Brasil.
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spelling Salomão, KellyPereira, Paulo Roberto S.Campos, Leila C.Borba, Cintia M.Cabello, Pedro H.Marcucci, Maria CristinaCastro, Solange L. de2018-08-14T14:38:27Z2018-08-14T14:38:27Z2008SALOMÃO, Kelly; et al. Brazilian Propolis: Correlation Between Chemical Composition and Antimicrobial Activity. eCAM, v.5, n.3, p.317-314, 2008.1741-427Xhttps://www.arca.fiocruz.br/handle/icict/2813110.1093/ecam/nem0581741-427XengHindawi Publishing CorporationTrypanosoma cruziPropolisatividade bactericidacomposição químicaanálise estatísticaatividade fungicidaBrasilbactericidal activitychemical compositionfungicidal activitypropolisstatistical analysisTrypanosoma cruziBrazilBrazilian propolis: correlation between chemical composition and antimicrobial activityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bacteriologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Micologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Genética. Rio de Janeiro, RJ. Brasil.Universidade Bandeirante de São Paulo. Núcleo de Pós-graduação, Pesquisa e Extensão. São Paulo, SP. BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Rio de Janeiro, RJ. Brasil.The chemical composition of ethanol extracts from samples of Brazilian propolis (EEPs) determined by HPLC and their activity against Trypanosoma cruzi, Staphylococcus aureus, Streptococcus pneumoniae, Klebisiella pneumoniae, Candida albicans, Sporothrix schenckii and Paracoccidioides brasiliensis were determined. Based on the predominant botanical origin in the region of samples' collection, the 10 extracts were separated into three groups: A (B. dracunculifolia + Auraucaria spp), B (B. dracunculifolia) and C (Araucaria spp). Analysis by the multiple regression of all the extracts together showed a positive correlation, higher concentrations leading to higher biological effect, of S. aureus with p-coumaric acid (PCUM) and 3-(4-hydroxy-3-(oxo-butenyl)-phenylacrylic acid (DHCA1) and of trypomastigotes of T. cruzi with 3,5-diprenyl-4-hydroxycinnamic acid derivative 4 (DHCA4) and 2,2-dimethyl-6-carboxyethenyl-2H-1-benzopyran (DCBEN). When the same approach was employed for each group, due to the small number of observations, the statistical test gave unreliable results. However, an overall analysis revealed for group A an association of S. aureus with caffeic acid (CAF) and dicaffeoylquinic acid 3 (CAFQ3), of S. pneumoniae with CAFQ3 and monocaffeoylquinic acid 2 (CAFQ2) and of T. cruzi also with CAFQ3. For group B, a higher activity against S. pneumoniae was associated DCBEN and for T. cruzi with CAF. For group C no association was observed between the anitmicrobial effect and any component of the extracts. The present study reinforces the relevance of PCUM and derivatives, especially prenylated ones and also of caffeolyquinic acids, on the biological activity of Brazilian propolis.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/28131/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALkelly_salomao_etal_IOC_2008.pdfkelly_salomao_etal_IOC_2008.pdfapplication/pdf256931https://www.arca.fiocruz.br/bitstream/icict/28131/2/kelly_salomao_etal_IOC_2008.pdf8a94aae96678970dec6ff214133deb55MD52TEXTkelly_salomao_etal_IOC_2008.pdf.txtkelly_salomao_etal_IOC_2008.pdf.txtExtracted texttext/plain30544https://www.arca.fiocruz.br/bitstream/icict/28131/3/kelly_salomao_etal_IOC_2008.pdf.txt50c793de12cb25b73fb3f16dcadc7bdcMD53icict/281312018-08-15 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dc.title.pt_BR.fl_str_mv Brazilian propolis: correlation between chemical composition and antimicrobial activity
title Brazilian propolis: correlation between chemical composition and antimicrobial activity
spellingShingle Brazilian propolis: correlation between chemical composition and antimicrobial activity
Salomão, Kelly
Trypanosoma cruzi
Propolis
atividade bactericida
composição química
análise estatística
atividade fungicida
Brasil
bactericidal activity
chemical composition
fungicidal activity
propolis
statistical analysis
Trypanosoma cruzi
Brazil
title_short Brazilian propolis: correlation between chemical composition and antimicrobial activity
title_full Brazilian propolis: correlation between chemical composition and antimicrobial activity
title_fullStr Brazilian propolis: correlation between chemical composition and antimicrobial activity
title_full_unstemmed Brazilian propolis: correlation between chemical composition and antimicrobial activity
title_sort Brazilian propolis: correlation between chemical composition and antimicrobial activity
author Salomão, Kelly
author_facet Salomão, Kelly
Pereira, Paulo Roberto S.
Campos, Leila C.
Borba, Cintia M.
Cabello, Pedro H.
Marcucci, Maria Cristina
Castro, Solange L. de
author_role author
author2 Pereira, Paulo Roberto S.
Campos, Leila C.
Borba, Cintia M.
Cabello, Pedro H.
Marcucci, Maria Cristina
Castro, Solange L. de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Salomão, Kelly
Pereira, Paulo Roberto S.
Campos, Leila C.
Borba, Cintia M.
Cabello, Pedro H.
Marcucci, Maria Cristina
Castro, Solange L. de
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
Propolis
atividade bactericida
composição química
análise estatística
atividade fungicida
Brasil
topic Trypanosoma cruzi
Propolis
atividade bactericida
composição química
análise estatística
atividade fungicida
Brasil
bactericidal activity
chemical composition
fungicidal activity
propolis
statistical analysis
Trypanosoma cruzi
Brazil
dc.subject.en.pt_BR.fl_str_mv bactericidal activity
chemical composition
fungicidal activity
propolis
statistical analysis
Trypanosoma cruzi
Brazil
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Ultra-estrutura e Biologia Celular. Rio de Janeiro, RJ. Brasil.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2018-08-14T14:38:27Z
dc.date.available.fl_str_mv 2018-08-14T14:38:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SALOMÃO, Kelly; et al. Brazilian Propolis: Correlation Between Chemical Composition and Antimicrobial Activity. eCAM, v.5, n.3, p.317-314, 2008.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/28131
dc.identifier.issn.pt_BR.fl_str_mv 1741-427X
dc.identifier.doi.none.fl_str_mv 10.1093/ecam/nem058
dc.identifier.eissn.none.fl_str_mv 1741-427X
identifier_str_mv SALOMÃO, Kelly; et al. Brazilian Propolis: Correlation Between Chemical Composition and Antimicrobial Activity. eCAM, v.5, n.3, p.317-314, 2008.
1741-427X
10.1093/ecam/nem058
url https://www.arca.fiocruz.br/handle/icict/28131
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/28131/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/28131/2/kelly_salomao_etal_IOC_2008.pdf
https://www.arca.fiocruz.br/bitstream/icict/28131/3/kelly_salomao_etal_IOC_2008.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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