High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil

Detalhes bibliográficos
Autor(a) principal: Assunção, Lucimar Gonçalves de Souza
Data de Publicação: 2012
Outros Autores: Santos, Silvana Maria Elói, Peixoto, Sérgio William Viana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/59505
Resumo: Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil.
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spelling Assunção, Lucimar Gonçalves de SouzaSantos, Silvana Maria ElóiPeixoto, Sérgio William Viana2023-07-11T13:19:43Z2023-07-11T13:19:43Z2012ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012.0100-879Xhttps://www.arca.fiocruz.br/handle/icict/5950510.1590/S0100-879X2012007500154engAssociação Brasileira de Divulgação CientíficaHigh sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil / Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Propedêutica Complementar. Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais. Escola de Enfermagem. Departamento de Enfermagem Aplicada. Belo Horizonte, MG, Brazil / Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil.The measurement of the serum concentration of the acute-phase reactant C-reactive protein (CRP) provides a useful marker in clinical practice. However, the distribution of CRP is not available for all age and population groups. This study assessed the distribution of high sensitivity CRP (hs-CRP) by gender and age in 1470 elderly individuals from a Brazilian community that participates in the Bambui Cohort Study. Blood samples were collected after 12 h of fasting and serum samples were stored at -70 degrees C. Measurements were made with a commercial hs-CRP immunonephelometric instrument. More than 50% of the results were above 3.0 mg/L for both genders. Mean hs-CRP was higher in women (3.62 +/- 2.58 mg/L) than in men (3.03 +/- 2.50 mg/L). This difference was observed for all ages, except for the over-80 age group. This is the first population-based study to describe hs-CRP values in Latin American elderly subjects. Our results indicate that significant gender differences exist in the distribution of hs-CRP, and suggest that gender-specific cut-off points for hs-CRP would be necessary for the prediction of cardiovascular risks.C-reactive proteinElderlyEpidemiologyCardiovascular riskBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALindex.pdfindex.pdfapplication/pdf163599https://www.arca.fiocruz.br/bitstream/icict/59505/2/index.pdfed4d79c2d0cf507b22e44632e373b86fMD52LICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/59505/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51icict/595052023-07-11 10:22:20.845oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-07-11T13:22:20Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
title High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
spellingShingle High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
Assunção, Lucimar Gonçalves de Souza
C-reactive protein
Elderly
Epidemiology
Cardiovascular risk
Brazil
title_short High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
title_full High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
title_fullStr High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
title_full_unstemmed High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
title_sort High sensitivity C-reactive protein distribution in the elderly: the Bambui Cohort Study, Brazil
author Assunção, Lucimar Gonçalves de Souza
author_facet Assunção, Lucimar Gonçalves de Souza
Santos, Silvana Maria Elói
Peixoto, Sérgio William Viana
author_role author
author2 Santos, Silvana Maria Elói
Peixoto, Sérgio William Viana
author2_role author
author
dc.contributor.author.fl_str_mv Assunção, Lucimar Gonçalves de Souza
Santos, Silvana Maria Elói
Peixoto, Sérgio William Viana
dc.subject.en.en_US.fl_str_mv C-reactive protein
Elderly
Epidemiology
Cardiovascular risk
Brazil
topic C-reactive protein
Elderly
Epidemiology
Cardiovascular risk
Brazil
description Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Patologia. Belo Horizonte, MG, Brazil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2023-07-11T13:19:43Z
dc.date.available.fl_str_mv 2023-07-11T13:19:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/59505
dc.identifier.issn.en_US.fl_str_mv 0100-879X
dc.identifier.doi.none.fl_str_mv 10.1590/S0100-879X2012007500154
identifier_str_mv ASSUNÇÃO, Lucimar Gonçalves de Souza; SANTOS, Silvana Maria Elói; PEIXOTO, Sérgio William Viana. High sensitivity C-reactive protein distribution in the elderly: the Bambuí Cohort Study, Brazil. Brazilian Journal of Medical and Biological Research, v. 45, n. 12, p. 1284-1286, 2012.
0100-879X
10.1590/S0100-879X2012007500154
url https://www.arca.fiocruz.br/handle/icict/59505
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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