A Novel Potentiometric Sensor for the Determination of Nimesulide

Detalhes bibliográficos
Autor(a) principal: Kumar,K.G.
Data de Publicação: 2007
Outros Autores: Augustine,P., John,S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007
Resumo: A novel electrochemical sensor has been developed for the determination of nimesulide. The sensor is based on the NIM- molybdophosphoric acid (MPA) as the electroactive material in PVC matrix in presence of bis(2-ethyl hexyl) phthalate (BEP) as a plasticizer. The sensor showed a fast, stable, near Nernstian response for 1 ´ 10-2 -1 ´ 10-6 M NIM over the pH range 5 - 8 with a slope 55.6 ±0.5m V/decade and the response time is < 45 s. Selectivity coefficient data for some common ions show negligible interferences. The sensor was successfully applied for the determination of NIM in tablet and the results obtained are in good agreement with those obtained by the official method.
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spelling A Novel Potentiometric Sensor for the Determination of NimesulideNimesulidePVC membrane sensorsmolybdophosphoric acidpotentiometric determinationpharmaceutical analysisA novel electrochemical sensor has been developed for the determination of nimesulide. The sensor is based on the NIM- molybdophosphoric acid (MPA) as the electroactive material in PVC matrix in presence of bis(2-ethyl hexyl) phthalate (BEP) as a plasticizer. The sensor showed a fast, stable, near Nernstian response for 1 ´ 10-2 -1 ´ 10-6 M NIM over the pH range 5 - 8 with a slope 55.6 ±0.5m V/decade and the response time is < 45 s. Selectivity coefficient data for some common ions show negligible interferences. The sensor was successfully applied for the determination of NIM in tablet and the results obtained are in good agreement with those obtained by the official method.Sociedade Portuguesa de Electroquímica2007-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007Portugaliae Electrochimica Acta v.25 n.3 2007reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007Kumar,K.G.Augustine,P.John,S.info:eu-repo/semantics/openAccess2024-02-06T17:06:52Zoai:scielo:S0872-19042007000300007Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:20:02.942777Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A Novel Potentiometric Sensor for the Determination of Nimesulide
title A Novel Potentiometric Sensor for the Determination of Nimesulide
spellingShingle A Novel Potentiometric Sensor for the Determination of Nimesulide
Kumar,K.G.
Nimesulide
PVC membrane sensors
molybdophosphoric acid
potentiometric determination
pharmaceutical analysis
title_short A Novel Potentiometric Sensor for the Determination of Nimesulide
title_full A Novel Potentiometric Sensor for the Determination of Nimesulide
title_fullStr A Novel Potentiometric Sensor for the Determination of Nimesulide
title_full_unstemmed A Novel Potentiometric Sensor for the Determination of Nimesulide
title_sort A Novel Potentiometric Sensor for the Determination of Nimesulide
author Kumar,K.G.
author_facet Kumar,K.G.
Augustine,P.
John,S.
author_role author
author2 Augustine,P.
John,S.
author2_role author
author
dc.contributor.author.fl_str_mv Kumar,K.G.
Augustine,P.
John,S.
dc.subject.por.fl_str_mv Nimesulide
PVC membrane sensors
molybdophosphoric acid
potentiometric determination
pharmaceutical analysis
topic Nimesulide
PVC membrane sensors
molybdophosphoric acid
potentiometric determination
pharmaceutical analysis
description A novel electrochemical sensor has been developed for the determination of nimesulide. The sensor is based on the NIM- molybdophosphoric acid (MPA) as the electroactive material in PVC matrix in presence of bis(2-ethyl hexyl) phthalate (BEP) as a plasticizer. The sensor showed a fast, stable, near Nernstian response for 1 ´ 10-2 -1 ´ 10-6 M NIM over the pH range 5 - 8 with a slope 55.6 ±0.5m V/decade and the response time is < 45 s. Selectivity coefficient data for some common ions show negligible interferences. The sensor was successfully applied for the determination of NIM in tablet and the results obtained are in good agreement with those obtained by the official method.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Electroquímica
publisher.none.fl_str_mv Sociedade Portuguesa de Electroquímica
dc.source.none.fl_str_mv Portugaliae Electrochimica Acta v.25 n.3 2007
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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