A Novel Potentiometric Sensor for the Determination of Nimesulide
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007 |
Resumo: | A novel electrochemical sensor has been developed for the determination of nimesulide. The sensor is based on the NIM- molybdophosphoric acid (MPA) as the electroactive material in PVC matrix in presence of bis(2-ethyl hexyl) phthalate (BEP) as a plasticizer. The sensor showed a fast, stable, near Nernstian response for 1 ´ 10-2 -1 ´ 10-6 M NIM over the pH range 5 - 8 with a slope 55.6 ±0.5m V/decade and the response time is < 45 s. Selectivity coefficient data for some common ions show negligible interferences. The sensor was successfully applied for the determination of NIM in tablet and the results obtained are in good agreement with those obtained by the official method. |
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A Novel Potentiometric Sensor for the Determination of NimesulideNimesulidePVC membrane sensorsmolybdophosphoric acidpotentiometric determinationpharmaceutical analysisA novel electrochemical sensor has been developed for the determination of nimesulide. The sensor is based on the NIM- molybdophosphoric acid (MPA) as the electroactive material in PVC matrix in presence of bis(2-ethyl hexyl) phthalate (BEP) as a plasticizer. The sensor showed a fast, stable, near Nernstian response for 1 ´ 10-2 -1 ´ 10-6 M NIM over the pH range 5 - 8 with a slope 55.6 ±0.5m V/decade and the response time is < 45 s. Selectivity coefficient data for some common ions show negligible interferences. The sensor was successfully applied for the determination of NIM in tablet and the results obtained are in good agreement with those obtained by the official method.Sociedade Portuguesa de Electroquímica2007-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007Portugaliae Electrochimica Acta v.25 n.3 2007reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007Kumar,K.G.Augustine,P.John,S.info:eu-repo/semantics/openAccess2024-02-06T17:06:52Zoai:scielo:S0872-19042007000300007Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:20:02.942777Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
title |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
spellingShingle |
A Novel Potentiometric Sensor for the Determination of Nimesulide Kumar,K.G. Nimesulide PVC membrane sensors molybdophosphoric acid potentiometric determination pharmaceutical analysis |
title_short |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
title_full |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
title_fullStr |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
title_full_unstemmed |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
title_sort |
A Novel Potentiometric Sensor for the Determination of Nimesulide |
author |
Kumar,K.G. |
author_facet |
Kumar,K.G. Augustine,P. John,S. |
author_role |
author |
author2 |
Augustine,P. John,S. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Kumar,K.G. Augustine,P. John,S. |
dc.subject.por.fl_str_mv |
Nimesulide PVC membrane sensors molybdophosphoric acid potentiometric determination pharmaceutical analysis |
topic |
Nimesulide PVC membrane sensors molybdophosphoric acid potentiometric determination pharmaceutical analysis |
description |
A novel electrochemical sensor has been developed for the determination of nimesulide. The sensor is based on the NIM- molybdophosphoric acid (MPA) as the electroactive material in PVC matrix in presence of bis(2-ethyl hexyl) phthalate (BEP) as a plasticizer. The sensor showed a fast, stable, near Nernstian response for 1 ´ 10-2 -1 ´ 10-6 M NIM over the pH range 5 - 8 with a slope 55.6 ±0.5m V/decade and the response time is < 45 s. Selectivity coefficient data for some common ions show negligible interferences. The sensor was successfully applied for the determination of NIM in tablet and the results obtained are in good agreement with those obtained by the official method. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042007000300007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Electroquímica |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Electroquímica |
dc.source.none.fl_str_mv |
Portugaliae Electrochimica Acta v.25 n.3 2007 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
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1799137289834594304 |