Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/25692 |
Resumo: | Continuous-flow precipitation of hydroxyapatite (HAp) was investigated in a meso oscillatory flow reactor (meso- OFR) and in a scaled-up meso-OFR, obtained by associating in series eight vertical meso-ORFs. Experiments were carried out under near-physiological conditions of temperature and pH, using fixed frequency ( f = 0.83 Hz) and amplitude (x0 = 4.5 mm), and varying the residence time from 0.4 to 6.7 min. It has been shown that the mean particle size and the aggregation degree of the prepared HAp particles decrease with decreasing residence time. HAp nanoparticles with a mean size (d50) of 77 nm, narrow size distribution, and uniform morphology were obtained at the lowest residence times, τ = 0.4 and 3.3 min in the meso-OFR and the scaled-up meso-OFR, respectively. These results show the capability of the meso-OFR and the scaled-up meso-OFR for continuous production of uniform HAp nanoparticles, while also confirming the possibility of OFR scale-up by in series association of individual OFRs. |
id |
RCAP_a32ef6830256bb3894346aecb8c9d0b3 |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/25692 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactorScience & TechnologyContinuous-flow precipitation of hydroxyapatite (HAp) was investigated in a meso oscillatory flow reactor (meso- OFR) and in a scaled-up meso-OFR, obtained by associating in series eight vertical meso-ORFs. Experiments were carried out under near-physiological conditions of temperature and pH, using fixed frequency ( f = 0.83 Hz) and amplitude (x0 = 4.5 mm), and varying the residence time from 0.4 to 6.7 min. It has been shown that the mean particle size and the aggregation degree of the prepared HAp particles decrease with decreasing residence time. HAp nanoparticles with a mean size (d50) of 77 nm, narrow size distribution, and uniform morphology were obtained at the lowest residence times, τ = 0.4 and 3.3 min in the meso-OFR and the scaled-up meso-OFR, respectively. These results show the capability of the meso-OFR and the scaled-up meso-OFR for continuous production of uniform HAp nanoparticles, while also confirming the possibility of OFR scale-up by in series association of individual OFRs.American Chemical SocietyAmerican Chemical SocietyUniversidade do MinhoCastro, FilipaFerreira, AntónioRocha, FernandoVicente, A. A.Teixeira, J. A.20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/25692eng0888-58851520-504510.1021/ie400710binfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:41:28Zoai:repositorium.sdum.uminho.pt:1822/25692Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:38:27.751201Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
title |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
spellingShingle |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor Castro, Filipa Science & Technology |
title_short |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
title_full |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
title_fullStr |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
title_full_unstemmed |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
title_sort |
Continuous-flow precipitation of hydroxyapatite at 37 °C in a meso oscillatory flow reactor |
author |
Castro, Filipa |
author_facet |
Castro, Filipa Ferreira, António Rocha, Fernando Vicente, A. A. Teixeira, J. A. |
author_role |
author |
author2 |
Ferreira, António Rocha, Fernando Vicente, A. A. Teixeira, J. A. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Castro, Filipa Ferreira, António Rocha, Fernando Vicente, A. A. Teixeira, J. A. |
dc.subject.por.fl_str_mv |
Science & Technology |
topic |
Science & Technology |
description |
Continuous-flow precipitation of hydroxyapatite (HAp) was investigated in a meso oscillatory flow reactor (meso- OFR) and in a scaled-up meso-OFR, obtained by associating in series eight vertical meso-ORFs. Experiments were carried out under near-physiological conditions of temperature and pH, using fixed frequency ( f = 0.83 Hz) and amplitude (x0 = 4.5 mm), and varying the residence time from 0.4 to 6.7 min. It has been shown that the mean particle size and the aggregation degree of the prepared HAp particles decrease with decreasing residence time. HAp nanoparticles with a mean size (d50) of 77 nm, narrow size distribution, and uniform morphology were obtained at the lowest residence times, τ = 0.4 and 3.3 min in the meso-OFR and the scaled-up meso-OFR, respectively. These results show the capability of the meso-OFR and the scaled-up meso-OFR for continuous production of uniform HAp nanoparticles, while also confirming the possibility of OFR scale-up by in series association of individual OFRs. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013 2013-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/25692 |
url |
http://hdl.handle.net/1822/25692 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0888-5885 1520-5045 10.1021/ie400710b |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
American Chemical Society American Chemical Society |
publisher.none.fl_str_mv |
American Chemical Society American Chemical Society |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799132921777356800 |