Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi

Detalhes bibliográficos
Autor(a) principal: Almeida, Maria Angela Ornelas de
Data de Publicação: 2005
Outros Autores: Jesus, E. E. V., Atta, Maria Luiza Brito de Sousa, Alves, L. C., Berne, M. E. A., Atta, Ajax Mercês
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6603
Resumo: Trabalho completo: acesso restrito, p. 227–232
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spelling Almeida, Maria Angela Ornelas deJesus, E. E. V.Atta, Maria Luiza Brito de SousaAlves, L. C.Berne, M. E. A.Atta, Ajax MercêsAlmeida, Maria Angela Ornelas deJesus, E. E. V.Atta, Maria Luiza Brito de SousaAlves, L. C.Berne, M. E. A.Atta, Ajax Mercês2012-08-17T19:41:02Z2005-02-280304-4017http://www.repositorio.ufba.br/ri/handle/ri/6603v. 127, n. 3–4Trabalho completo: acesso restrito, p. 227–232Human visceral leishmaniasis is endemic in the northeast of Brazil, where the domestic dog is an important parasite reservoir in the infectious cycle of Leishmania chagasi. In this study, we evaluated the clinical signs of canine visceral leishmaniasis (CVL), serum protein profile and the antileishmanial IgG antibody production in 86 dogs living in northeast endemic areas of leishmaniasis. Thirty dogs from a leishmaniasis-free area were used as a control group. The major clinical signs of CVL seen were emaciation and skin ulcers (80%), followed by onychogryphosis and conjunctivitis (73%). Depilation was observed in 60% of animals while lymphadenomegaly, splenomegaly, liver enlargement or kidney involvement was less frequent (≤20%). VL seropositive dogs presented with serum hyperproteinemia, hypoalbuminemia, hypergammaglobulinemia and decreased albumin/globulin ratio. A lower sensitivity and higher specificity was observed for promastigote indirect fluorescent antibody test (IFAT) (83 and 100%, respectively) compared with enzyme-linked immunosorbent assay (ELISA) (94 and 90%), which uses a crude extract of Leishmania. There was a positive correlation between IFAT and ELISA titers of antileishmanial IgG antibodies (Spearman test, P < 0.05), which was augmented in CVL dogs. This study found that the determination of serum protein, A/G ratio and the use of two different leishmanial serological tests like IFAT and ELISA are essential in CVL screening.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-08-17T19:41:02Z No. of bitstreams: 1 (168).pdf: 108889 bytes, checksum: affa48e64ad4a7f1c026c912874f79ff (MD5)Made available in DSpace on 2012-08-17T19:41:02Z (GMT). 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dc.title.pt_BR.fl_str_mv Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
dc.title.alternative.pt_BR.fl_str_mv Veterinary Parasitology
title Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
spellingShingle Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
Almeida, Maria Angela Ornelas de
Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
title_short Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_full Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_fullStr Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_full_unstemmed Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
title_sort Clinical and serological aspects of visceral leishmaniasis in Northeast Brazilian dogs naturally infected with Leishmania chagasi
author Almeida, Maria Angela Ornelas de
author_facet Almeida, Maria Angela Ornelas de
Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
author_role author
author2 Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Almeida, Maria Angela Ornelas de
Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
Almeida, Maria Angela Ornelas de
Jesus, E. E. V.
Atta, Maria Luiza Brito de Sousa
Alves, L. C.
Berne, M. E. A.
Atta, Ajax Mercês
dc.subject.por.fl_str_mv Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
topic Leishmania chagasi
Natural canine visceral leishmaniasis
Clinical signs and laboratory markers
description Trabalho completo: acesso restrito, p. 227–232
publishDate 2005
dc.date.issued.fl_str_mv 2005-02-28
dc.date.accessioned.fl_str_mv 2012-08-17T19:41:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6603
dc.identifier.issn.none.fl_str_mv 0304-4017
dc.identifier.number.pt_BR.fl_str_mv v. 127, n. 3–4
identifier_str_mv 0304-4017
v. 127, n. 3–4
url http://www.repositorio.ufba.br/ri/handle/ri/6603
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.vetpar.2004.10.010
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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