Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil

Detalhes bibliográficos
Autor(a) principal: Grimaldi, Rogerio
Data de Publicação: 2010
Outros Autores: Acosta, Angelina Xavier, Machado, Taisa Manuela Bonfim, Bomfim, Thaís Ferreira, Galvão, Castro B. I.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5910
Resumo: Trabalho completo: acesso restrito, p. 197-200
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spelling Grimaldi, RogerioAcosta, Angelina XavierMachado, Taisa Manuela BonfimBomfim, Thaís FerreiraGalvão, Castro B. I.Grimaldi, RogerioAcosta, Angelina XavierMachado, Taisa Manuela BonfimBomfim, Thaís FerreiraGalvão, Castro B. I.2012-05-17T19:58:59Z2010-041413-8670http://www.repositorio.ufba.br/ri/handle/ri/5910v.14, n. 2Trabalho completo: acesso restrito, p. 197-200A mutation described as a G-to-A transition has been reported in SDF-1 gene (SDF1-3'A), being prevalent in all ethnic groups, except in Africans. This mutation is associated with the onset of AIDS progression. Our aim was to identify the frequency of this allele in different groups from Brazil: Tiriyó and Waiampi Amerindian tribes (Asian ancestry); selected blood donors from Joinville (German descendents); and from Salvador (predominance of African and Portuguese mixture). SDF1-3'A was screened by PCR/RFLP with MspI enzyme. Our results showed a high allelic frequency in Tiriyó tribe (0.24) and Joinville population (0.21), and a frequency of 0.17 and 0.05 in the Salvador population and in the Waiampi tribe, respectively. There was no statistical difference among the allelic frequencies in the studied ethnic groups, except in the Waiampi. Due to the great genetic diversity among Brazilian population and the lack of studies on SDF1-3'A allele, our study of this allelic frequency in these different Brazilian ethnic groups could be important to identification of biomarker for therapeutic support in progression to AIDS and a molecular marker for analysis of evolutionary relationships among human populations.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-05-17T19:58:59Z No. of bitstreams: 1 (25)v14n2a17.pdf: 733112 bytes, checksum: 52b7800ffff58770c219e97018e8e887 (MD5)Made available in DSpace on 2012-05-17T19:58:59Z (GMT). No. of bitstreams: 1 (25)v14n2a17.pdf: 733112 bytes, checksum: 52b7800ffff58770c219e97018e8e887 (MD5) Previous issue date: 2010-04Scielohttp://dx.doi.org/10.1590/S1413-86702010000200017reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBASDF1-3'A polymorphismbrazilian populationHIV-1 co-receptorDistribution of SDF1-3'A polymorphisms in three different ethnic groups from BrazilBrazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5910/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINAL(25)v14n2a17.pdf(25)v14n2a17.pdfapplication/pdf733112https://repositorio.ufba.br/bitstream/ri/5910/1/%2825%29v14n2a17.pdf52b7800ffff58770c219e97018e8e887MD51TEXT(25)v14n2a17.pdf.txt(25)v14n2a17.pdf.txtExtracted texttext/plain21611https://repositorio.ufba.br/bitstream/ri/5910/3/%2825%29v14n2a17.pdf.txta9f12e646d1553135b3dac2fa394e370MD53ri/59102022-07-05 14:03:11.252oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:11Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
dc.title.alternative.pt_BR.fl_str_mv Brazilian Journal of Infectious Diseases
title Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
spellingShingle Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
Grimaldi, Rogerio
SDF1-3'A polymorphism
brazilian population
HIV-1 co-receptor
title_short Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
title_full Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
title_fullStr Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
title_full_unstemmed Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
title_sort Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
author Grimaldi, Rogerio
author_facet Grimaldi, Rogerio
Acosta, Angelina Xavier
Machado, Taisa Manuela Bonfim
Bomfim, Thaís Ferreira
Galvão, Castro B. I.
author_role author
author2 Acosta, Angelina Xavier
Machado, Taisa Manuela Bonfim
Bomfim, Thaís Ferreira
Galvão, Castro B. I.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Grimaldi, Rogerio
Acosta, Angelina Xavier
Machado, Taisa Manuela Bonfim
Bomfim, Thaís Ferreira
Galvão, Castro B. I.
Grimaldi, Rogerio
Acosta, Angelina Xavier
Machado, Taisa Manuela Bonfim
Bomfim, Thaís Ferreira
Galvão, Castro B. I.
dc.subject.por.fl_str_mv SDF1-3'A polymorphism
brazilian population
HIV-1 co-receptor
topic SDF1-3'A polymorphism
brazilian population
HIV-1 co-receptor
description Trabalho completo: acesso restrito, p. 197-200
publishDate 2010
dc.date.issued.fl_str_mv 2010-04
dc.date.accessioned.fl_str_mv 2012-05-17T19:58:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5910
dc.identifier.issn.none.fl_str_mv 1413-8670
dc.identifier.number.pt_BR.fl_str_mv v.14, n. 2
identifier_str_mv 1413-8670
v.14, n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/5910
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Scielo
publisher.none.fl_str_mv Scielo
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S1413-86702010000200017
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
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