Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age

Detalhes bibliográficos
Autor(a) principal: Lêda Maria da Costa Pinheiro Frota
Data de Publicação: 2020
Outros Autores: Rosana Ferreira Sampaio, José Lucivan Miranda, Rita Maria Cavalcante Brasil, Ana Paula Bensemann Gontijo, Juliana Vaz de Melo Mambrini, Marina de Brito Brandao, Marisa Cotta Mancini
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.1016/j.heliyon.2020.e04130
http://hdl.handle.net/1843/65211
https://orcid.org/0000-0001-5192-0868
Resumo: CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
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spelling 2024-03-04T22:25:31Z2024-03-04T22:25:31Z202066e041308https://doi.org/10.1016/j.heliyon.2020.e041302405-8440http://hdl.handle.net/1843/65211https://orcid.org/0000-0001-5192-0868CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorBackground Children with congenital Zika syndrome (CZS) maintain severe motor impairments at the end of the first year of life. Presence of certain symptoms and comorbidities increase these children's vulnerability. Aims To evaluate gross motor function of a group of Brazilian children with CZS at 24 months of age and to investigate the association between the presence of CZS symptoms and comorbidities with gross motor development. Methods and procedures Fifty children with CZS participated in the study. Information was collected from medical charts, and gross motor development was evaluated by the Gross Motor Function Measure (GMFM)-88. GMFM-88 scores were compared among comorbid groups. Three subgroups of children were identified by cluster analysis, based on information from head circumference at birth, symptoms, comorbidities and gross motor function. Outcomes and results Significant associations (p < 0.001) were observed between number of comorbidities/symptoms and dimensions A (r = -0.57) and B (r = -0.58) of the GMFM-88. Children were grouped into 3 clusters, with different gross motor skills. Children with epilepsy and dysphagia composed the cluster with smaller median scores for dimensions A and B of the GMFM-88. Conclusions and implications The presence of CZS symptoms and comorbidities compromise the gross motor repertoire of children with CZS at 24 months.engUniversidade Federal de Minas GeraisUFMGBrasilEEF - DEPARTAMENTO DE FISIOTERAPIAEEF - DEPARTAMENTO DE TERAPIA OCUPACIONALEEFFTO - ESCOLA DE EDUCAÇÃO FISICA, FISIOTERAPIA E TERAPIA OCUPACIONALHeliyonSaúde públicaEpilepsiaMicrocefaliaTranstornos de DeglutiçãoVírus da ZikaPediatriaVirologiaNeuroscienceVirologyDisabilityMusculoskeletal systemNervous systemPediatricsHealth promotionZika virusMicrocephalyDysphagiaEpilepsyMotor skillsChildren with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of ageinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.sciencedirect.com/science/article/pii/S2405844020309749?via%3DihubLêda Maria da Costa Pinheiro FrotaRosana Ferreira SampaioJosé Lucivan MirandaRita Maria Cavalcante BrasilAna Paula Bensemann GontijoJuliana Vaz de Melo MambriniMarina de Brito BrandaoMarisa Cotta Manciniapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/65211/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALChildren with congenital Zika syndrome_ symptoms, comorbidities and gross motor development at 24 months of age.pdfChildren with congenital Zika syndrome_ symptoms, comorbidities and gross motor development at 24 months of age.pdfapplication/pdf943405https://repositorio.ufmg.br/bitstream/1843/65211/2/Children%20with%20congenital%20Zika%20syndrome_%20symptoms%2c%20comorbidities%20and%20gross%20motor%20development%20at%2024%20months%20of%20age.pdf4061ca238bca915cd04ba664ce09a397MD521843/652112024-03-04 19:25:32.112oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2024-03-04T22:25:32Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
title Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
spellingShingle Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
Lêda Maria da Costa Pinheiro Frota
Neuroscience
Virology
Disability
Musculoskeletal system
Nervous system
Pediatrics
Health promotion
Zika virus
Microcephaly
Dysphagia
Epilepsy
Motor skills
Saúde pública
Epilepsia
Microcefalia
Transtornos de Deglutição
Vírus da Zika
Pediatria
Virologia
title_short Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
title_full Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
title_fullStr Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
title_full_unstemmed Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
title_sort Children with congenital Zika syndrome: symptoms, comorbidities and gross motor development at 24 months of age
author Lêda Maria da Costa Pinheiro Frota
author_facet Lêda Maria da Costa Pinheiro Frota
Rosana Ferreira Sampaio
José Lucivan Miranda
Rita Maria Cavalcante Brasil
Ana Paula Bensemann Gontijo
Juliana Vaz de Melo Mambrini
Marina de Brito Brandao
Marisa Cotta Mancini
author_role author
author2 Rosana Ferreira Sampaio
José Lucivan Miranda
Rita Maria Cavalcante Brasil
Ana Paula Bensemann Gontijo
Juliana Vaz de Melo Mambrini
Marina de Brito Brandao
Marisa Cotta Mancini
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lêda Maria da Costa Pinheiro Frota
Rosana Ferreira Sampaio
José Lucivan Miranda
Rita Maria Cavalcante Brasil
Ana Paula Bensemann Gontijo
Juliana Vaz de Melo Mambrini
Marina de Brito Brandao
Marisa Cotta Mancini
dc.subject.por.fl_str_mv Neuroscience
Virology
Disability
Musculoskeletal system
Nervous system
Pediatrics
Health promotion
Zika virus
Microcephaly
Dysphagia
Epilepsy
Motor skills
topic Neuroscience
Virology
Disability
Musculoskeletal system
Nervous system
Pediatrics
Health promotion
Zika virus
Microcephaly
Dysphagia
Epilepsy
Motor skills
Saúde pública
Epilepsia
Microcefalia
Transtornos de Deglutição
Vírus da Zika
Pediatria
Virologia
dc.subject.other.pt_BR.fl_str_mv Saúde pública
Epilepsia
Microcefalia
Transtornos de Deglutição
Vírus da Zika
Pediatria
Virologia
description CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2024-03-04T22:25:31Z
dc.date.available.fl_str_mv 2024-03-04T22:25:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/65211
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.1016/j.heliyon.2020.e04130
dc.identifier.issn.pt_BR.fl_str_mv 2405-8440
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0001-5192-0868
url https://doi.org/10.1016/j.heliyon.2020.e04130
http://hdl.handle.net/1843/65211
https://orcid.org/0000-0001-5192-0868
identifier_str_mv 2405-8440
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Heliyon
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv EEF - DEPARTAMENTO DE FISIOTERAPIA
EEF - DEPARTAMENTO DE TERAPIA OCUPACIONAL
EEFFTO - ESCOLA DE EDUCAÇÃO FISICA, FISIOTERAPIA E TERAPIA OCUPACIONAL
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
bitstream.url.fl_str_mv https://repositorio.ufmg.br/bitstream/1843/65211/1/License.txt
https://repositorio.ufmg.br/bitstream/1843/65211/2/Children%20with%20congenital%20Zika%20syndrome_%20symptoms%2c%20comorbidities%20and%20gross%20motor%20development%20at%2024%20months%20of%20age.pdf
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repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
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