Hand sanitizer gel formulations: Influence of polymer type on the rheological properties
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2024 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/45531 |
Resumo: | COVID-19 increased the demand for alcohol-based hand sanitizer in establishments. The present study aimed to characterize different polymers and/or polymer mixtures with the potential to be used to produce alcohol-based gel hand sanitizers and evaluate the different formulations of alcohol gel as to their rheological properties. Polymers and polymer blends (natural and/or synthetic) were characterized by DSC and FTIR/NIR analysis. Six were polymers or blends of polymers efficient to production of this product in the concentration of 70% ethanol (w/w). Alcohol-based hand sanitizer gel formulations were stored at two different temperatures (25 °C and 40 °C) and subjected to rheological analysis over the storage time (0, 7, 14, and 28 days). The rheological profile indicated a behavior of pseudoplastic fluid of the samples, and they remained stable throughout the days of storage at 25 °C. Formulations containing natural polymers derived from cellulose are good alternatives to replace the carbomer gelling agent, with limitations related to the reduction of the gel apparent viscosity. |
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Hand sanitizer gel formulations: Influence of polymer type on the rheological propertiesFormulaciones de gel desinfectante para manos: Influencia del tipo de polímero en las propiedades reológicasFormulações de gel higienizante de mãos: Influência do tipo de polímero nas propriedades reológicas Alcohol en gelCOVID-19Agentes gelificantesPolímerosEstabilidad.Álcool em gelCOVID-19Agentes gelificantesPolímerosEstabilidade.Alcohol gelCOVID-19Gelling agentsPolymersStability.COVID-19 increased the demand for alcohol-based hand sanitizer in establishments. The present study aimed to characterize different polymers and/or polymer mixtures with the potential to be used to produce alcohol-based gel hand sanitizers and evaluate the different formulations of alcohol gel as to their rheological properties. Polymers and polymer blends (natural and/or synthetic) were characterized by DSC and FTIR/NIR analysis. Six were polymers or blends of polymers efficient to production of this product in the concentration of 70% ethanol (w/w). Alcohol-based hand sanitizer gel formulations were stored at two different temperatures (25 °C and 40 °C) and subjected to rheological analysis over the storage time (0, 7, 14, and 28 days). The rheological profile indicated a behavior of pseudoplastic fluid of the samples, and they remained stable throughout the days of storage at 25 °C. Formulations containing natural polymers derived from cellulose are good alternatives to replace the carbomer gelling agent, with limitations related to the reduction of the gel apparent viscosity.El COVID-19 incrementó la demanda de desinfectante para manos a base de alcohol en los establecimientos. El presente estudio tuvo como objetivo caracterizar diferentes polímeros y/o mezclas de polímeros con potencial para ser utilizados para producir desinfectantes para manos en gel a base de alcohol y evaluar las diferentes formulaciones de alcohol en gel en cuanto a sus propiedades reológicas. Los polímeros y mezclas de polímeros (naturales y/o sintéticos) se caracterizaron mediante análisis DSC y FTIR/NIR. Seis eran polímeros o mezclas de polímeros eficientes para la producción de este producto en una concentración de 70% de etanol (p/p). Las formulaciones de gel desinfectante para manos a base de alcohol se almacenaron a dos temperaturas diferentes (25 °C y 40 °C) y se sometieron a análisis reológico durante el tiempo de almacenamiento (0, 7, 14 y 28 días). El perfil reológico indicó un comportamiento de fluido pseudoplástico de las muestras, y se mantuvieron estables durante los días de almacenamiento a 25 °C. Las formulaciones que contienen polímeros naturales derivados de la celulosa son buenas alternativas para reemplazar el agente gelificante carbómero, con limitaciones relacionadas con la reducción de la viscosidad aparente del gel.A COVID-19 aumentou a procura por desinfetantes para as mãos à base de álcool nos estabelecimentos. O presente estudo teve como objetivo caracterizar diferentes polímeros e/ou misturas de polímeros com potencial para serem utilizados na produção de álcool em gel para higienização das mãos e avaliar as diferentes formulações de álcool gel quanto às suas propriedades reológicas. Polímeros e misturas de polímeros (naturais e/ou sintéticos) foram caracterizados por análises de DSC e FTIR/NIR. Seis polímeros ou misturas de polímeros foram eficientes para a produção deste produto na concentração de 70% de etanol (m/m). As formulações de gel antisséptico para as mãos à base de álcool foram armazenadas em duas temperaturas diferentes (25 °C e 40 °C) e submetidas à análise reológica ao longo do tempo de armazenamento (0, 7, 14 e 28 dias). O perfil reológico indicou comportamento de fluido pseudoplástico nas amostras, que permaneceram estáveis ao longo dos dias de armazenamento a 25 °C. Formulações contendo polímeros naturais derivados de celulose são boas alternativas para substituir o agente gelificante carbômero, com limitações relacionadas à redução da viscosidade aparente do gel.Research, Society and Development2024-04-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4553110.33448/rsd-v13i4.45531Research, Society and Development; Vol. 13 No. 4; e6313445531Research, Society and Development; Vol. 13 Núm. 4; e6313445531Research, Society and Development; v. 13 n. 4; e63134455312525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/45531/36282Copyright (c) 2024 Gardenia Barbosa Carrijo Rodrigues; Josemar Gonçalves de Oliveira Filho ; Adriano Jakelaitis; Elton Clementino da Silva; Geovana Rocha Placido; Suzana Maria Loures de Oliveria Marcionilio; Raphaela Gabrí Bitencourthttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRodrigues, Gardenia Barbosa Carrijo Oliveira Filho , Josemar Gonçalves de Jakelaitis, Adriano Silva, Elton Clementino da Placido, Geovana Rocha Marcionilio, Suzana Maria Loures de Oliveria Bitencourt, Raphaela Gabrí2024-04-04T18:36:37Zoai:ojs.pkp.sfu.ca:article/45531Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-04-04T18:36:37Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties Formulaciones de gel desinfectante para manos: Influencia del tipo de polímero en las propiedades reológicas Formulações de gel higienizante de mãos: Influência do tipo de polímero nas propriedades reológicas |
| title |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties |
| spellingShingle |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties Rodrigues, Gardenia Barbosa Carrijo Alcohol en gel COVID-19 Agentes gelificantes Polímeros Estabilidad. Álcool em gel COVID-19 Agentes gelificantes Polímeros Estabilidade. Alcohol gel COVID-19 Gelling agents Polymers Stability. |
| title_short |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties |
| title_full |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties |
| title_fullStr |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties |
| title_full_unstemmed |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties |
| title_sort |
Hand sanitizer gel formulations: Influence of polymer type on the rheological properties |
| author |
Rodrigues, Gardenia Barbosa Carrijo |
| author_facet |
Rodrigues, Gardenia Barbosa Carrijo Oliveira Filho , Josemar Gonçalves de Jakelaitis, Adriano Silva, Elton Clementino da Placido, Geovana Rocha Marcionilio, Suzana Maria Loures de Oliveria Bitencourt, Raphaela Gabrí |
| author_role |
author |
| author2 |
Oliveira Filho , Josemar Gonçalves de Jakelaitis, Adriano Silva, Elton Clementino da Placido, Geovana Rocha Marcionilio, Suzana Maria Loures de Oliveria Bitencourt, Raphaela Gabrí |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Rodrigues, Gardenia Barbosa Carrijo Oliveira Filho , Josemar Gonçalves de Jakelaitis, Adriano Silva, Elton Clementino da Placido, Geovana Rocha Marcionilio, Suzana Maria Loures de Oliveria Bitencourt, Raphaela Gabrí |
| dc.subject.por.fl_str_mv |
Alcohol en gel COVID-19 Agentes gelificantes Polímeros Estabilidad. Álcool em gel COVID-19 Agentes gelificantes Polímeros Estabilidade. Alcohol gel COVID-19 Gelling agents Polymers Stability. |
| topic |
Alcohol en gel COVID-19 Agentes gelificantes Polímeros Estabilidad. Álcool em gel COVID-19 Agentes gelificantes Polímeros Estabilidade. Alcohol gel COVID-19 Gelling agents Polymers Stability. |
| description |
COVID-19 increased the demand for alcohol-based hand sanitizer in establishments. The present study aimed to characterize different polymers and/or polymer mixtures with the potential to be used to produce alcohol-based gel hand sanitizers and evaluate the different formulations of alcohol gel as to their rheological properties. Polymers and polymer blends (natural and/or synthetic) were characterized by DSC and FTIR/NIR analysis. Six were polymers or blends of polymers efficient to production of this product in the concentration of 70% ethanol (w/w). Alcohol-based hand sanitizer gel formulations were stored at two different temperatures (25 °C and 40 °C) and subjected to rheological analysis over the storage time (0, 7, 14, and 28 days). The rheological profile indicated a behavior of pseudoplastic fluid of the samples, and they remained stable throughout the days of storage at 25 °C. Formulations containing natural polymers derived from cellulose are good alternatives to replace the carbomer gelling agent, with limitations related to the reduction of the gel apparent viscosity. |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024-04-17 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/45531 10.33448/rsd-v13i4.45531 |
| url |
https://rsdjournal.org/index.php/rsd/article/view/45531 |
| identifier_str_mv |
10.33448/rsd-v13i4.45531 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/45531/36282 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
| dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 13 No. 4; e6313445531 Research, Society and Development; Vol. 13 Núm. 4; e6313445531 Research, Society and Development; v. 13 n. 4; e6313445531 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052639861538816 |