Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1508/cytologia.68.395 http://hdl.handle.net/11449/67509 |
Resumo: | The comet assay has been described as an efficient tool for the detection of changes in the DNA molecule of cells exposed to contaminating agents in vivo and in vitro. The possible environmental contamination due to the persistence of chromium residues from tannery effluents was determined in the waters of the Córrego dos Bagres stream, Municipal district of Franca/SP, by the comet assay on CHO-K1 cells. Water samples were collected during the four seasons of the year 2001 at three distinct stations along the river. The data suggest that the comet test showed good sensitivity for the environmental monitoring of these waters and indicated that this test can be efficient for the determination of the quality of waters contaminated with effluents containing heavy metal residues such as chromium. |
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Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet AssayCHO-K1ChromiumComet assayGenotoxicityThe comet assay has been described as an efficient tool for the detection of changes in the DNA molecule of cells exposed to contaminating agents in vivo and in vitro. The possible environmental contamination due to the persistence of chromium residues from tannery effluents was determined in the waters of the Córrego dos Bagres stream, Municipal district of Franca/SP, by the comet assay on CHO-K1 cells. Water samples were collected during the four seasons of the year 2001 at three distinct stations along the river. The data suggest that the comet test showed good sensitivity for the environmental monitoring of these waters and indicated that this test can be efficient for the determination of the quality of waters contaminated with effluents containing heavy metal residues such as chromium.Univ. Fed. do Espírito Santo Depto. de Cie. Biológicas, Av. Marechal Campus 1468, CEP: 29040-090, Vitória/ESUniversidade Estadual de Londrina Departamento de Biologia Geral, Cx. Postal. 601, CEP: 86051-990, Londrina/PRUniversidade Estadual Paulista-UNESP 1B-Campus de Rio Claro, Av.24-A, 1515, CEP: 13506-900, Rio Claro/SPUniversidade Estadual Paulista-UNESP 1B-Campus de Rio Claro, Av.24-A, 1515, CEP: 13506-900, Rio Claro/SPDepto. de Cie. BiológicasUniversidade Estadual de Londrina (UEL)Universidade Estadual Paulista (Unesp)Matsumoto, Silvia TamieMantovani, Mário SérgioMallaguti, Mirtis I. [UNESP]Marin-Morales, Maria Aparecida [UNESP]2014-05-27T11:20:57Z2014-05-27T11:20:57Z2003-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article395-401application/pdfhttp://dx.doi.org/10.1508/cytologia.68.395Cytologia, v. 68, n. 4, p. 395-401, 2003.0011-4545http://hdl.handle.net/11449/6750910.1508/cytologia.68.3952-s2.0-03470312742-s2.0-0347031274.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCytologia0.4810,233info:eu-repo/semantics/openAccess2023-11-12T06:10:46Zoai:repositorio.unesp.br:11449/67509Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:26:58.770710Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
title |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
spellingShingle |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay Matsumoto, Silvia Tamie CHO-K1 Chromium Comet assay Genotoxicity |
title_short |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
title_full |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
title_fullStr |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
title_full_unstemmed |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
title_sort |
Investigation of the Genotoxic Potential of the Waters of a River Receiving Tannery Effluents by Means of the in vitro Comet Assay |
author |
Matsumoto, Silvia Tamie |
author_facet |
Matsumoto, Silvia Tamie Mantovani, Mário Sérgio Mallaguti, Mirtis I. [UNESP] Marin-Morales, Maria Aparecida [UNESP] |
author_role |
author |
author2 |
Mantovani, Mário Sérgio Mallaguti, Mirtis I. [UNESP] Marin-Morales, Maria Aparecida [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Depto. de Cie. Biológicas Universidade Estadual de Londrina (UEL) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Matsumoto, Silvia Tamie Mantovani, Mário Sérgio Mallaguti, Mirtis I. [UNESP] Marin-Morales, Maria Aparecida [UNESP] |
dc.subject.por.fl_str_mv |
CHO-K1 Chromium Comet assay Genotoxicity |
topic |
CHO-K1 Chromium Comet assay Genotoxicity |
description |
The comet assay has been described as an efficient tool for the detection of changes in the DNA molecule of cells exposed to contaminating agents in vivo and in vitro. The possible environmental contamination due to the persistence of chromium residues from tannery effluents was determined in the waters of the Córrego dos Bagres stream, Municipal district of Franca/SP, by the comet assay on CHO-K1 cells. Water samples were collected during the four seasons of the year 2001 at three distinct stations along the river. The data suggest that the comet test showed good sensitivity for the environmental monitoring of these waters and indicated that this test can be efficient for the determination of the quality of waters contaminated with effluents containing heavy metal residues such as chromium. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-12-01 2014-05-27T11:20:57Z 2014-05-27T11:20:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1508/cytologia.68.395 Cytologia, v. 68, n. 4, p. 395-401, 2003. 0011-4545 http://hdl.handle.net/11449/67509 10.1508/cytologia.68.395 2-s2.0-0347031274 2-s2.0-0347031274.pdf |
url |
http://dx.doi.org/10.1508/cytologia.68.395 http://hdl.handle.net/11449/67509 |
identifier_str_mv |
Cytologia, v. 68, n. 4, p. 395-401, 2003. 0011-4545 10.1508/cytologia.68.395 2-s2.0-0347031274 2-s2.0-0347031274.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Cytologia 0.481 0,233 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
395-401 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128814070366208 |