Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles

Detalhes bibliográficos
Autor(a) principal: Favretto, Carla Oliveira [UNESP]
Data de Publicação: 2018
Outros Autores: Delbem, Alberto Carlos Botazzo [UNESP], Moraes, João Carlos Silos [UNESP], Camargo, Emerson Rodrigues, de Toledo, Priscila Toninatto Alves [UNESP], Pedrini, Denise [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/s00784-018-2384-3
http://hdl.handle.net/11449/175912
Resumo: Objectives: This in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). Materials and methods: The dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05). Results: Toothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards. Conclusions: It was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. Clinical relevance: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity.
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spelling Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticlesCalcium phosphatesCollagenEnergy-dispersive X-ray spectroscopyFluoridesNanoparticlesX-ray microtomographyObjectives: This in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). Materials and methods: The dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05). Results: Toothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards. Conclusions: It was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. Clinical relevance: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity.Department of Pediatric Dentistry and Public Health School of Dentistry Araçatuba São Paulo State University (UNESP)Department of Physics and Chemistry São Paulo State University (UNESP)Department of Chemistry Federal University of São Carlos – UFSCARDepartment of Surgery and Integrated Clinic School of Dentistry Araçatuba São Paulo State University (UNESP)Disciplina de Clínica Integrada Faculdade de Odontologia do Campus de Araçatuba, Rua José Bonifácio 1193, CEPDepartment of Pediatric Dentistry and Public Health School of Dentistry Araçatuba São Paulo State University (UNESP)Department of Physics and Chemistry São Paulo State University (UNESP)Department of Surgery and Integrated Clinic School of Dentistry Araçatuba São Paulo State University (UNESP)Universidade Estadual Paulista (Unesp)Universidade Federal de São Carlos (UFSCar)Faculdade de Odontologia do Campus de AraçatubaFavretto, Carla Oliveira [UNESP]Delbem, Alberto Carlos Botazzo [UNESP]Moraes, João Carlos Silos [UNESP]Camargo, Emerson Rodriguesde Toledo, Priscila Toninatto Alves [UNESP]Pedrini, Denise [UNESP]2018-12-11T17:18:06Z2018-12-11T17:18:06Z2018-02-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-9application/pdfhttp://dx.doi.org/10.1007/s00784-018-2384-3Clinical Oral Investigations, p. 1-9.1436-37711432-6981http://hdl.handle.net/11449/17591210.1007/s00784-018-2384-32-s2.0-850422337202-s2.0-85042233720.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Oral Investigations0,9860,986info:eu-repo/semantics/openAccess2024-09-19T17:56:15Zoai:repositorio.unesp.br:11449/175912Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-19T17:56:15Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
title Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
spellingShingle Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
Favretto, Carla Oliveira [UNESP]
Calcium phosphates
Collagen
Energy-dispersive X-ray spectroscopy
Fluorides
Nanoparticles
X-ray microtomography
title_short Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
title_full Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
title_fullStr Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
title_full_unstemmed Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
title_sort Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
author Favretto, Carla Oliveira [UNESP]
author_facet Favretto, Carla Oliveira [UNESP]
Delbem, Alberto Carlos Botazzo [UNESP]
Moraes, João Carlos Silos [UNESP]
Camargo, Emerson Rodrigues
de Toledo, Priscila Toninatto Alves [UNESP]
Pedrini, Denise [UNESP]
author_role author
author2 Delbem, Alberto Carlos Botazzo [UNESP]
Moraes, João Carlos Silos [UNESP]
Camargo, Emerson Rodrigues
de Toledo, Priscila Toninatto Alves [UNESP]
Pedrini, Denise [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal de São Carlos (UFSCar)
Faculdade de Odontologia do Campus de Araçatuba
dc.contributor.author.fl_str_mv Favretto, Carla Oliveira [UNESP]
Delbem, Alberto Carlos Botazzo [UNESP]
Moraes, João Carlos Silos [UNESP]
Camargo, Emerson Rodrigues
de Toledo, Priscila Toninatto Alves [UNESP]
Pedrini, Denise [UNESP]
dc.subject.por.fl_str_mv Calcium phosphates
Collagen
Energy-dispersive X-ray spectroscopy
Fluorides
Nanoparticles
X-ray microtomography
topic Calcium phosphates
Collagen
Energy-dispersive X-ray spectroscopy
Fluorides
Nanoparticles
X-ray microtomography
description Objectives: This in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). Materials and methods: The dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05). Results: Toothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards. Conclusions: It was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. Clinical relevance: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-11T17:18:06Z
2018-12-11T17:18:06Z
2018-02-20
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s00784-018-2384-3
Clinical Oral Investigations, p. 1-9.
1436-3771
1432-6981
http://hdl.handle.net/11449/175912
10.1007/s00784-018-2384-3
2-s2.0-85042233720
2-s2.0-85042233720.pdf
url http://dx.doi.org/10.1007/s00784-018-2384-3
http://hdl.handle.net/11449/175912
identifier_str_mv Clinical Oral Investigations, p. 1-9.
1436-3771
1432-6981
10.1007/s00784-018-2384-3
2-s2.0-85042233720
2-s2.0-85042233720.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clinical Oral Investigations
0,986
0,986
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-9
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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