Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s00784-018-2384-3 http://hdl.handle.net/11449/175912 |
Resumo: | Objectives: This in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). Materials and methods: The dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05). Results: Toothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards. Conclusions: It was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. Clinical relevance: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity. |
id |
UNSP_8e525872ca734e7ebb0511aac7ced4fa |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/175912 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticlesCalcium phosphatesCollagenEnergy-dispersive X-ray spectroscopyFluoridesNanoparticlesX-ray microtomographyObjectives: This in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). Materials and methods: The dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05). Results: Toothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards. Conclusions: It was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. Clinical relevance: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity.Department of Pediatric Dentistry and Public Health School of Dentistry Araçatuba São Paulo State University (UNESP)Department of Physics and Chemistry São Paulo State University (UNESP)Department of Chemistry Federal University of São Carlos – UFSCARDepartment of Surgery and Integrated Clinic School of Dentistry Araçatuba São Paulo State University (UNESP)Disciplina de Clínica Integrada Faculdade de Odontologia do Campus de Araçatuba, Rua José Bonifácio 1193, CEPDepartment of Pediatric Dentistry and Public Health School of Dentistry Araçatuba São Paulo State University (UNESP)Department of Physics and Chemistry São Paulo State University (UNESP)Department of Surgery and Integrated Clinic School of Dentistry Araçatuba São Paulo State University (UNESP)Universidade Estadual Paulista (Unesp)Universidade Federal de São Carlos (UFSCar)Faculdade de Odontologia do Campus de AraçatubaFavretto, Carla Oliveira [UNESP]Delbem, Alberto Carlos Botazzo [UNESP]Moraes, João Carlos Silos [UNESP]Camargo, Emerson Rodriguesde Toledo, Priscila Toninatto Alves [UNESP]Pedrini, Denise [UNESP]2018-12-11T17:18:06Z2018-12-11T17:18:06Z2018-02-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-9application/pdfhttp://dx.doi.org/10.1007/s00784-018-2384-3Clinical Oral Investigations, p. 1-9.1436-37711432-6981http://hdl.handle.net/11449/17591210.1007/s00784-018-2384-32-s2.0-850422337202-s2.0-85042233720.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Oral Investigations0,9860,986info:eu-repo/semantics/openAccess2024-09-19T17:56:15Zoai:repositorio.unesp.br:11449/175912Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-19T17:56:15Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
title |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
spellingShingle |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles Favretto, Carla Oliveira [UNESP] Calcium phosphates Collagen Energy-dispersive X-ray spectroscopy Fluorides Nanoparticles X-ray microtomography |
title_short |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
title_full |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
title_fullStr |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
title_full_unstemmed |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
title_sort |
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles |
author |
Favretto, Carla Oliveira [UNESP] |
author_facet |
Favretto, Carla Oliveira [UNESP] Delbem, Alberto Carlos Botazzo [UNESP] Moraes, João Carlos Silos [UNESP] Camargo, Emerson Rodrigues de Toledo, Priscila Toninatto Alves [UNESP] Pedrini, Denise [UNESP] |
author_role |
author |
author2 |
Delbem, Alberto Carlos Botazzo [UNESP] Moraes, João Carlos Silos [UNESP] Camargo, Emerson Rodrigues de Toledo, Priscila Toninatto Alves [UNESP] Pedrini, Denise [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal de São Carlos (UFSCar) Faculdade de Odontologia do Campus de Araçatuba |
dc.contributor.author.fl_str_mv |
Favretto, Carla Oliveira [UNESP] Delbem, Alberto Carlos Botazzo [UNESP] Moraes, João Carlos Silos [UNESP] Camargo, Emerson Rodrigues de Toledo, Priscila Toninatto Alves [UNESP] Pedrini, Denise [UNESP] |
dc.subject.por.fl_str_mv |
Calcium phosphates Collagen Energy-dispersive X-ray spectroscopy Fluorides Nanoparticles X-ray microtomography |
topic |
Calcium phosphates Collagen Energy-dispersive X-ray spectroscopy Fluorides Nanoparticles X-ray microtomography |
description |
Objectives: This in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). Materials and methods: The dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05). Results: Toothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards. Conclusions: It was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. Clinical relevance: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-11T17:18:06Z 2018-12-11T17:18:06Z 2018-02-20 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s00784-018-2384-3 Clinical Oral Investigations, p. 1-9. 1436-3771 1432-6981 http://hdl.handle.net/11449/175912 10.1007/s00784-018-2384-3 2-s2.0-85042233720 2-s2.0-85042233720.pdf |
url |
http://dx.doi.org/10.1007/s00784-018-2384-3 http://hdl.handle.net/11449/175912 |
identifier_str_mv |
Clinical Oral Investigations, p. 1-9. 1436-3771 1432-6981 10.1007/s00784-018-2384-3 2-s2.0-85042233720 2-s2.0-85042233720.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinical Oral Investigations 0,986 0,986 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-9 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1813546411093917696 |