The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.phytol.2020.01.019 http://hdl.handle.net/11449/201524 |
Resumo: | Two new polyketides, named koninginin T (1) and U (2), were isolated from Phomopsis stipata - an endophytic fungus isolated from Styrax camporum Pohl. The structures of polyketides 1 and 2 were defined through the analysis of spectroscopic data. Antifungal and acetylcholinesterase inhibitory activities of these compounds were evaluated using TLC bioautographic assays. Compounds 1 and 2 displayed moderate antifungal activity and compound 1 showed acetylcholinesterase inhibitory activity. |
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Repositório Institucional da UNESP |
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spelling |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum PohlAcetylcholinesterase inhibitors.AntifungalKoningininPhomopsis stipataPolyketidesTwo new polyketides, named koninginin T (1) and U (2), were isolated from Phomopsis stipata - an endophytic fungus isolated from Styrax camporum Pohl. The structures of polyketides 1 and 2 were defined through the analysis of spectroscopic data. Antifungal and acetylcholinesterase inhibitory activities of these compounds were evaluated using TLC bioautographic assays. Compounds 1 and 2 displayed moderate antifungal activity and compound 1 showed acetylcholinesterase inhibitory activity.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Organic Chemistry Department São Paulo State University UNESP Chemistry InstituteEnvironmental Chemistry Federal University of Tocantins UFTDepartment of Phytochemistry Medicinal Plants and Drugs Research Institute Shahid Beheshti University, EvinInstitute of Technological and Exact Sciences Federal University of ViçosaFederal University of Mato Grosso Department of Biological SciencesInstitute of Botany of São PauloPhytopathology Department Federal University of LavrasOrganic Chemistry Department São Paulo State University UNESP Chemistry InstituteFAPESP: 03/02176-7Universidade Estadual Paulista (Unesp)UFTShahid Beheshti UniversityFederal University of ViçosaFederal University of Mato GrossoInstitute of Botany of São PauloFederal University of LavrasBiasetto, Carolina R. [UNESP]Somensi, Andressa [UNESP]Sordi, Renata [UNESP]Chapla, Vanessa M.Ebrahimi, Samad N.Silva, Geraldo H.Teles, Helder L.Bolzani, Vanderlan da S. [UNESP]Young, Maria Cláudia M.Pfenning, Ludwig H.Araujo, Angela R. [UNESP]2020-12-12T02:34:51Z2020-12-12T02:34:51Z2020-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article106-110http://dx.doi.org/10.1016/j.phytol.2020.01.019Phytochemistry Letters, v. 36, p. 106-110.1876-74861874-3900http://hdl.handle.net/11449/20152410.1016/j.phytol.2020.01.0192-s2.0-85078977888Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPhytochemistry Lettersinfo:eu-repo/semantics/openAccess2021-10-22T20:11:26Zoai:repositorio.unesp.br:11449/201524Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-06T00:04:55.736213Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
title |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
spellingShingle |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl Biasetto, Carolina R. [UNESP] Acetylcholinesterase inhibitors. Antifungal Koninginin Phomopsis stipata Polyketides |
title_short |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
title_full |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
title_fullStr |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
title_full_unstemmed |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
title_sort |
The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl |
author |
Biasetto, Carolina R. [UNESP] |
author_facet |
Biasetto, Carolina R. [UNESP] Somensi, Andressa [UNESP] Sordi, Renata [UNESP] Chapla, Vanessa M. Ebrahimi, Samad N. Silva, Geraldo H. Teles, Helder L. Bolzani, Vanderlan da S. [UNESP] Young, Maria Cláudia M. Pfenning, Ludwig H. Araujo, Angela R. [UNESP] |
author_role |
author |
author2 |
Somensi, Andressa [UNESP] Sordi, Renata [UNESP] Chapla, Vanessa M. Ebrahimi, Samad N. Silva, Geraldo H. Teles, Helder L. Bolzani, Vanderlan da S. [UNESP] Young, Maria Cláudia M. Pfenning, Ludwig H. Araujo, Angela R. [UNESP] |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) UFT Shahid Beheshti University Federal University of Viçosa Federal University of Mato Grosso Institute of Botany of São Paulo Federal University of Lavras |
dc.contributor.author.fl_str_mv |
Biasetto, Carolina R. [UNESP] Somensi, Andressa [UNESP] Sordi, Renata [UNESP] Chapla, Vanessa M. Ebrahimi, Samad N. Silva, Geraldo H. Teles, Helder L. Bolzani, Vanderlan da S. [UNESP] Young, Maria Cláudia M. Pfenning, Ludwig H. Araujo, Angela R. [UNESP] |
dc.subject.por.fl_str_mv |
Acetylcholinesterase inhibitors. Antifungal Koninginin Phomopsis stipata Polyketides |
topic |
Acetylcholinesterase inhibitors. Antifungal Koninginin Phomopsis stipata Polyketides |
description |
Two new polyketides, named koninginin T (1) and U (2), were isolated from Phomopsis stipata - an endophytic fungus isolated from Styrax camporum Pohl. The structures of polyketides 1 and 2 were defined through the analysis of spectroscopic data. Antifungal and acetylcholinesterase inhibitory activities of these compounds were evaluated using TLC bioautographic assays. Compounds 1 and 2 displayed moderate antifungal activity and compound 1 showed acetylcholinesterase inhibitory activity. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:34:51Z 2020-12-12T02:34:51Z 2020-04-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.phytol.2020.01.019 Phytochemistry Letters, v. 36, p. 106-110. 1876-7486 1874-3900 http://hdl.handle.net/11449/201524 10.1016/j.phytol.2020.01.019 2-s2.0-85078977888 |
url |
http://dx.doi.org/10.1016/j.phytol.2020.01.019 http://hdl.handle.net/11449/201524 |
identifier_str_mv |
Phytochemistry Letters, v. 36, p. 106-110. 1876-7486 1874-3900 10.1016/j.phytol.2020.01.019 2-s2.0-85078977888 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Phytochemistry Letters |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
106-110 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129581155090432 |