Ecological, Genetic, and Phylogenetic Aspects of YFV 2017–2019 Spread in Rio de Janeiro State

• Autor(a) principal: Ribeiro, Ieda Pereira
• Data de Publicação: 2023
• Outros Autores: Delatorre, Edson, Abreu, Filipe Vieira Santos de, Santos, Alexandre Araújo Cunha dos, Furtado, Nathália Dias, Ferreira-de-Brito, Anielly, Pina-Costa, Anielle de, Neves, Maycon Sebastião Alberto Santos, Castro, Márcia Gonçalves de, Motta, Monique de Albuquerque, Brasil, Patricia, Lourenço-de-Oliveira, Ricardo, Bonaldo, Myrna Cristina
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
• DOI: 10.3390/v15020437
• Texto Completo: https://www.arca.fiocruz.br/handle/icict/58977
• topic: Brazilian outbreak; Amino acid polymorphisms; Ecology; Epidemiology; Genomic surveillance; Yellow fever virus

Institutional Review Board Statement: The study was conducted in accordance with the Declaration of Helsinki, and approved by the Institutional Ethics Committee of Instituto Oswaldo Cruz (IOC) (CAAE 69206217.8.0000.5248), which exempted the need for specific written informed consent from patients or their legal representatives. The animal study protocol was approved by the Institutional Ethics Committee of Brazilian Ministry of Environment (SISBIO 41837-3—20 May 2015, 52472-2—26 January 2016, and 54707-5—25 August 2016) and Rio de Janeiro’s Environment Agency (INEA 012/2016—07 February 2016 and 019/2018—19 April 2018) and by the institutional Ethics Committee for Animal Experimentation (protocol CEUA/IOC-004/2015—10 April 2015, licenseL037/2016—24 August 2016). Informed Consent Statement: Patient consent was waived due to the exemption of the Ethics Committee of Instituto Oswaldo Cruz. Data Availability Statement: Not applicable. Acknowledgments: To Gonzalo Bello for the inspiring insights, valuable discussions of methodological approaches and results throughout the outbreak, and study design. To Romário Gabriel Aquino (Environmental Surveillance, Secretaria Municipal de Saúde de Angra dos Reis), Tercius Barrada (Parque Estadual da Ilha Grande), Mário Sérgio Ribeiro and Patrícia Menegueti (Secretaria de Saúde do Estado do Rio de Janeiro), Prefeitura de Macaé, Centro de Estudos Ambientais e Desenvolvimento Sustentável (CEADS/UERJ), Marcelo Celestino dos Santos, Mauro M. Muniz, and Marcelo Q. Gomes for the help in obtaining the viral samples and support in the fieldwork. We are grateful to the Plataforma Genômica—Sequenciamento de DNA-RPT01A—Rede de Plataformas Tecnológicas FIOCRUZ for the services provided in the genome sequencing. We also thank Heloísa Diniz from Serviço de Produção e Tratamento de Imagens, IOC, Fiocruz, for the design of the figures.